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Study finds specific function of HIV protein that slows viral spread in early stages of infection

A study from a Massachusetts General Hospital research team has identified the specific function of a protein found in HIV and related viruses that appears to slow down viral spread in the earliest stages of infection.

11 Jan 2019

Researchers identify genetic risk factor for atypical heart attack in women

New research published by teams from Leicester, UK and Paris, France in collaboration with international partners from the US and Australia, has found a common genetic factor that confers a significant risk of atypical heart attacks in women.

7 Jan 2019

New strategy for developing cell replacement therapies to combat type 1 diabetes

Scientists have discovered the signals that determine the fate of immature cells in the pancreas. The research shows that they are very mobile and that their destiny is strongly influenced by their immediate environment.

29 Nov 2018

Scientists create mini-placenta's to study early stages of pregnancy

Researchers at the University of Cambridge have used organoid culture techniques to create a cellular model of the early stages of the placenta.

29 Nov 2018

Research explores how exercise may help fight drug addiction

The siren call of addictive drugs can be hard to resist, and returning to the environment where drugs were previously taken can make resistance that much harder.

14 Nov 2018

CNIO researchers link MASTL protein to origin of thrombocytopenia

The Cell Division and Cancer Group of the Spanish National Cancer Research Centre has discovered that MASTL, the protein whose function in the organism has not yet been sufficiently investigated, plays an important role in controlling the cytoskeleton, the structure that gives shape to the cells, and enables their mobility and capacity for grouping.

1 Nov 2018

Study reveals unknown mechanism that protects tumor cells from NK cell-mediated cytotoxicity

Cancer cells have evolved multiple escape strategies to circumvent the body's immune defenses such as the attack by Natural Killer (NK) cells which normally swiftly kill abnormal cells by releasing cytotoxic products.

24 Oct 2018

Study reveals factors linked to the development of Crohn's disease

How cells talk to each other, and what they say, has long held fascination for Seema Khurana, professor of biology and biochemistry.

5 Oct 2018

Drosophila study shows chromosomal instability promotes invasive behavior in human tumors

Metastatic tumors are characterized by a high degree of chromosomal instability--that is to say a constant change in the number and structure of chromosomes they hold. In spite of this observation, it is unknown whether chromosomal instability contributes to the metastatic process.

26 Sep 2018

New findings show importance of physical forces in tumor metastasis

A malignant tumor is characterized by its ability to spread around its surroundings. To do so, tumor cells stick to the surrounding tissue (mainly collagen) and use forces to propel.

26 Sep 2018

Novel micro-platform reveals never-before-seen behaviors of cancer cells

A new cell culture platform allows researchers to observe never-before-seen behaviors of live cancer cells under the microscope, leading to explanations of long-known cancer characteristics.

19 Sep 2018

People battling substance use disorders may benefit from meth-relapse prevention compound

New research raises the possibility that a wider group of people battling substance use disorders may benefit from a Scripps Research-developed relapse-prevention compound than previously thought.

17 Sep 2018

Researchers untangle mysteries of 'evil' protein in ER-positive breast cancer

Breast cancer is one of the most common cancers in the United States, striking 1 out of 8 women. About 80 percent of all breast cancers are estrogen receptor-positive, in which cancer growth is fueled by estrogen.

12 Sep 2018

Thrombospondin-1 contributes to development of aortic aneurysm in mice and humans, study finds

Researchers centered at the University of Tsukuba and Kansai Medical University in Japan reveal matricellular protein Thrombospondin-1 (Thbs1) contributes to the development of aortic aneurysm in mice and humans.

20 Aug 2018

Brown University researchers reveal key physical properties of 'giant' cancer cells

Polyploidal cancer cells--cells that have more than two copies of each chromosome--are much larger than most other cancer cells, are resistant to chemotherapy and radiation treatments and are associated with disease relapse.

14 Aug 2018

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Ashleigh Schaffer, PhD, assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty development process it triggers, causing a debilitating brain-based disorder in children.

9 Aug 2018

Actin News and Research

Study finds specific function of HIV protein that slows viral spread in early stages of infection

Researchers identify genetic risk factor for atypical heart attack in women

New strategy for developing cell replacement therapies to combat type 1 diabetes

Scientists create mini-placenta's to study early stages of pregnancy

Research explores how exercise may help fight drug addiction

CNIO researchers link MASTL protein to origin of thrombocytopenia

Study reveals unknown mechanism that protects tumor cells from NK cell-mediated cytotoxicity

Study reveals factors linked to the development of Crohn's disease

Drosophila study shows chromosomal instability promotes invasive behavior in human tumors

New findings show importance of physical forces in tumor metastasis

Novel micro-platform reveals never-before-seen behaviors of cancer cells

People battling substance use disorders may benefit from meth-relapse prevention compound

Researchers untangle mysteries of 'evil' protein in ER-positive breast cancer

Thrombospondin-1 contributes to development of aortic aneurysm in mice and humans, study finds

Brown University researchers reveal key physical properties of 'giant' cancer cells

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Defects in RNA modification can cause altered smooth muscle contraction

Scientists discover gene that predicts arthritis severity

Study reveals key role of actin cytoskeletal dynamics in supporting immune cell function

Discovery about how malaria moves could lead to new therapies

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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