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TSRI scientists discover natural mechanism that cells use to protect mitochondria

Scientists at The Scripps Research Institute have discovered a natural mechanism that cells use to protect mitochondria, the tiny but essential "power plants" that provide chemical energy for cells throughout the body. Damage to mitochondria is thought to be a significant factor in common neurodegenerative disorders, cancer and even the aging process. The TSRI researchers' discovery could lead to new methods for protecting mitochondria from such damage, thereby improving human health.

4 Dec 2013

Scientists use RNAi technology to reveal genes responsible for treating Parkinson's disease

Scientists at the National Institutes of Health have used RNA interference (RNAi) technology to reveal dozens of genes which may represent new therapeutic targets for treating Parkinson's disease. The findings also may be relevant to several diseases caused by damage to mitochondria, the biological power plants found in cells throughout the body.

24 Nov 2013

Copper intake via food and water can accelerate growth of tumors

Copper imbalances have been associated with a number of pathological conditions, including cancer. Publishing in PNAS scientists at EPFL have found that copper in drinking water - given at the maximum levels permitted in public water supplies - accelerated the growth of tumors in mice. On the other hand, reducing copper levels reduced tumor growth.

15 Nov 2013

Novel approach confirms dysfunctional energy production in schizophrenia

A method of directly assessing creatine kinase in the brain provides “direct and compelling” evidence for abnormal bioenergetics in the brains of patients with schizophrenia, say the study authors.

12 Nov 2013

Nutranomics provides update on GenEpic prostate cancer human clinical study

Nutranomics, Inc. is pleased to provide this update regarding the GenEpic prostate cancer human clinical study that is currently underway. Nutranomics has previously announced a non-binding Letter of Intent with Genesar Nutraceuticals, LLC with the intent of completing a licencing agreement to market and distribute GenEpic globally.

11 Nov 2013

Scientists investigate combined action of two different compounds against CML

Currently no treatment option is available for five percent of patients suffering from chronic myelogenous leukemia, since they have developed resistance to conventional medications. Prof. Stephan Grzesiek's group at the Biozentrum of the University of Basel, in collaboration with Dr. Wolfgang Jahnke and colleagues from Novartis, has investigated the combined action of two different compounds against this form of leukemia.

6 Nov 2013

NeuroAiD reduces early cardiovascular events and deaths by 50% after stroke onset

NeuroAiD™, a treatment of post-stroke recovery containing natural extracts, reduces early cardiovascular events and deaths by nearly 50% on top of antiplatelet agents within three months after stroke onset, without an increase in bleeding rate and non-vascular deaths according to research published online in the journal Stroke.

22 Oct 2013

Genes in mitochondria shape each person's risk for heart disease and diabetes

Genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's risk for heart disease and diabetes, according to a study published recently by researchers at the University of Alabama at Birmingham in the Biochemical Journal.

27 Sep 2013

Sodium-potassium pump is pivotal to body's function

The story of the sodium-potassium pump has strong ties to Denmark. In 1997, the Danish scientist Jens Chr. Skou received the Nobel Prize in Chemistry for his discovery, and over the years, research on the pump has remained a strong focus area at Aarhus University.

23 Sep 2013

PGI2 analogs, PDE5 inhibitors stimulate enhanced release of vasodilator ATP from human RBCs

Researchers at Saint Louis University School of Medicine have discovered a novel interaction between prostacyclin analogs and phosphodiesterase 5 inhibitors, two groups of drugs used in the treatment of pulmonary arterial hypertension.

21 Sep 2013

Video demonstrates high throughput screening of cellular bioenergetics of multiple cell lines

INTEGRA has published a video demonstrating how its VIAFLO 96 handheld electronic pipette, used in conjunction with the Seahorse Bioscience XF96 Extracellular Flux Analyzer, provides high throughput screening of the cellular bioenergetics of multiple cell lines.

From INTEGRA Biosciences 17 Sep 2013

Transport protein actively extrudes chemicals from embryo of zebrafish

Fish possess a number of different mechanisms for protection against harmful substances in an aquatic environment. These include, for example, molecular transport systems, such as the so called ABC (ATP binding cassette) transporters, which prevent the penetration of toxic substances into cells. ABC transporters have been well investigated for mammals.

3 Sep 2013

Study: Mother's mitochondrial DNA seems to influence our own aging

As we age, our cells change and become damaged. Now, researchers at Karolinska Institutet and the Max Planck Institute for Biology of Aging have shown that aging is determined not only by the accumulation of changes during our lifetime but also by the genes we acquire from our mothers.

22 Aug 2013

UCSF study shows potential for new treatment strategy for Parkinson’s disease

UC San Francisco scientists working in the lab used a chemical found in an anti-wrinkle cream to prevent the death of nerve cells damaged by mutations that cause an inherited form of Parkinson-s disease.

17 Aug 2013

Kinetin stops the effects of Parkinson's disease on brain cells, say scientists

The active ingredient in an over-the-counter skin cream might do more than prevent wrinkles. Scientists have discovered that the drug, called kinetin, also slows or stops the effects of Parkinson's disease on brain cells.

16 Aug 2013

Research shows how mammalian and bacterial kingdoms interact

The bacteria Streptococcus pneumoniae harmlessly colonizes the mucous linings of throats and noses in most people, only becoming virulent when they leave those comfortable surroundings and enter the middle ears, lungs or bloodstream. Now, in research published in July in mBio, University at Buffalo researchers reveal how that happens.

8 Aug 2013

Hospitals to face more severe penalties for patients' readmissions

News coverage continues regarding the Centers for Medicare & Medicaid Services' hospital readmissions reduction program with details of a final rule released Friday and a local look at how hospitals are faring in Georgia and Missouri.

7 Aug 2013

Nutritional supplement may prevent neurodegenerative disease affecting children

Researchers at the University of California, San Diego School of Medicine have identified the gene mutation responsible for a particularly severe form of pontocerebellar hypoplasia, a currently incurable neurodegenerative disease affecting children.

2 Aug 2013

Researchers find how brain cells communicate with each other in different voice tones

Brain cells talk to each other in a variety of tones. Sometimes they speak loudly but other times struggle to be heard. For many years scientists have asked why and how brain cells change tones so frequently. Today National Institutes of Health researchers showed that brief bursts of chemical energy coming from rapidly moving power plants, called mitochondria, may tune brain cell communication.

26 Jul 2013

Law of physics can be demonstrated by collection of individual protein molecules

Experiments by biochemists at the University of California, Davis show for the first time that a law of physics, the ergodic theorem, can be demonstrated by a collection of individual protein molecules -- specifically, a protein that unwinds DNA. The work will be published online by the journal Nature on July 14.

16 Jul 2013