Antibiotic Resistance News and Research

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FDA Advisory Committee votes in favor of Actavis' ceftazidime-avibactam

Actavis plc today announced that the Anti-Infective Drugs Advisory Committee convened by the U.S. Food and Drug Administration has voted to recommend approval of Actavis' New Drug Application (NDA) for ceftazidime-avibactam, an investigational antibiotic being developed to treat hospitalized patients when limited or no treatment options are available for complicated intra-abdominal infections (cIAI) (in combination with metronidazole) and complicated urinary tract infections (cUTI) (including acute pyelonephritis) caused by Gram-negative pathogens.

5 Dec 2014

World-renowned experts to discuss challenges of antibiotic resistance at Murdoch University symposium

World-renowned experts in the fields of antibiotic resistance will come together at a symposium at Murdoch University to talk about an issue which has the potential to become one of the world’s biggest public health challenges.

4 Dec 2014

Antibiotic resistance: Theme for next Uppsala Health Summit

The theme for the next Uppsala Health Summit, to be held in Uppsala on 2-3 June 2015, is antibiotic resistance -- one of the biggest global health challenges of our day.

2 Dec 2014

Researchers dismiss causal link between antibiotics treatment and childhood asthma

In a new register study in the scientific journal BMJ, researchers at Karolinska Institutet are able to dismiss previous claims that there is a link between the increased use of antibiotics in society and a coinciding rise in childhood asthma. The study includes half a million children and shows that exposure to antibiotics during pregnancy or early in life does not appear to increase the risk of asthma.

1 Dec 2014

New smartphone app may help improve prescribing of antibiotics within RCSI Hospitals Group

A new smartphone app has been developed by the RCSI (Royal College of Surgeons in Ireland) Hospitals Group, in association with the Dublin North East Healthcare-Associated Infection (HCAI) Committee, which will provide healthcare professionals in hospitals within the RCSI Hospitals Group with immediate access to guidelines for antimicrobial prescribing.

27 Nov 2014

Therapeutic nanoparticle safe, effective against H. pylori infection, shows study

The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers at University of California, San Diego School of Medicine and Jacobs School of Engineering developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils.

27 Nov 2014

Scientists develop new method to rapidly identify antibiotic resistance

Scientists from Uppsala University, the Science for Life Laboratory in Stockholm and Uppsala University Hospital have developed a new method of rapidly identifying which bacteria are causing an infection and determining whether they are resistant or sensitive to antibiotics.

24 Nov 2014

Unique ability helps prolific bacterium to afflict humans, animals and even plants

New research has found that one of the world's most prolific bacteria manages to afflict humans, animals and even plants by way of a mechanism not before seen in any infectious microorganism -- a sense of touch. This unique ability helps make the bacteria Pseudomonas aeruginosa ubiquitous, but it also might leave these antibiotic-resistant organisms vulnerable to a new form of treatment.

23 Nov 2014

NPS MedicineWise Reducing Antibiotic Resistance program focuses on urinary tract infections

The next phase of the NPS MedicineWise Reducing Antibiotic Resistance program for health professionals has launched today focused on the complex topic of managing urinary tract infections (UTIs).

21 Nov 2014

Three-day global symposium on Ebola virus, other infectious diseases

The 11th annual International Consortium on Anti-Virals (ICAV) symposium, Infectious Diseases: Global Public-Health Challenges of the Next Decade, will put the challenges posed by several infectious diseases under the microscope, including the Ebola virus, the H7N9 influenza virus, MERS coronavirus and dengue viruses, as well as drug-resistant tuberculosis.

18 Nov 2014

NPS MedicineWise calls all Australians to join the fight against antibiotic resistance

As Antibiotic Awareness Week 2014 is held across Australia from 17-23 November, NPS MedicineWise is asking all Australians to imagine a world without antibiotics and join the fight against antibiotic resistance.

17 Nov 2014

Representatives from 40 countries meet to discuss plan for antimicrobial resistance

Every year, 25,000 people die as a result of antimicrobial resistance in Europe. A global action plan against one of the greatest health threats of our time is the aim of a conference being held in Oslo on 13th-14th November.

14 Nov 2014

Researchers explore new ways to treat, prevent Streptococcus pneumoniae

Scientists from Massachusetts Eye and Ear/Harvard Medical School Department of Ophthalmology have used the power of new genomic technology to discover that microbes that commonly infect the eye have special, previously unknown properties. These properties are predicted to allow the bacterium -- Streptococcus pneumoniae -- to specifically stick to the surface of the eye, grow, and cause damage and inflammation.

13 Nov 2014

Antibiograms could improve antibiotic effectiveness, help address problems with antibiotic resistance

Use of "antibiograms" in skilled nursing facilities could improve antibiotic effectiveness and help address problems with antibiotic resistance that are becoming a national crisis, researchers conclude in a new study.

12 Nov 2014

New model explains how immune cells recognize, destroy bacteria

The innate immune system serves as the body's specialized armed forces division, comprised of a host of defense mechanisms used to battle bacterial infections. Among the system's warriors are white blood cells including the specialized macrophages, which maintain constant surveillance for foreign intruders or pathogens, functioning as the body's first line of defense, poised to attack at barrier sites including the skin, lungs and intestines.

11 Nov 2014

Ruthigen enrolls first patient in Phase 1/2 clinical trial of RUT58-60

Ruthigen, Inc., announced today enrollment of the first patient in a Randomized, Double-Blind Phase 1/2 clinical trial to evaluate the safety, tolerability, and potential efficacy of its lead drug candidate, RUT58-60, for use as an adjunct to systemic antibiotics in abdominal surgery.

4 Nov 2014

Research initiative focuses on microbial characteristics of Staphylococcus aureus

Staphylococcus aureus (Sa) and methicillin-resistant staph aureus (MRSA) continue to be among the most common pathogens that overwhelm the immune system, causing serious skin, soft tissue and life-threatening blood-borne infections.

16 Oct 2014

Pharmaceutical industry withdraws from the antibiotic space

The Centers for Disease Control and Prevention has said that at least 2 million Americans are sickened by antibiotic resistant infections each year and survive.

13 Oct 2014

Pneumococcal vaccine prevents illness, reduces severe antibiotic-resistant infections in young children

The pneumococcal vaccine recommended for young children not only prevents illness and death, but also has dramatically reduced severe antibiotic-resistant infections, suggests nationwide research being presented at IDWeek 2014.

12 Oct 2014

Vancomycin drug still effective in treating Staphylococcus aureus bloodstream infections

A University of Nebraska Medical Center research team has determined that a longtime antibiotic, vancomycin, is still effective in treating Staphylococcus aureus bloodstream infections and that physicians should continue to use the drug even though several newer antibiotics are now available in the marketplace.

10 Oct 2014