Antibodies News and Research

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Gene transfer used to deliver antibodies to fight Anthrax

Using gene transfer technology, investigators were able to immunize mice against anthrax in just 12 hours, according to new research featured in the February 2005 issue of Molecular Therapy, the peer-reviewed scientific journal of the American Society of Gene Therapy (ASGT).

12 Jan 2005

Safety established for Vaxin's first flu vaccine in clinical trial

Vaxin Inc., a privately-held biotechnology company, has demonstrated, in a Phase I human clinical study, that the company's recombinant influenza vaccine provides a potential alternative to traditional flu vaccines.

12 Jan 2005

Velcade (bortezomib) phase III clinical trial initiated in patients with newly diagnosed multiple myeloma

Millennium Pharmaceuticals today announced, in collaboration with Johnson & Johnson Pharmaceutical Research & Development, LLC, the initiation of VISTA (Velcadeas Initial Standard Therapy in multiple myeloma: Assessment with melphalan and prednisone), a multicenter, international phase III clinical trial of Velcadein combination with melphalan and prednisone versus melphalan and prednisone in patients with newly diagnosed multiple myeloma (MM) who are not transplant candidates.

10 Jan 2005

Scientists identify a protein that regulates alcohol-withdrawal seizures

Seizures are the most life-threatening, as well as disconcerting, symptoms of withdrawal in people who are alcoholics and who abruptly stop drinking. Heavy consumption of alcohol, or ethanol, the substance in beer, wine and liquor that is addictive, leads to changes in the brain.

10 Jan 2005

Australia attempts to develop treatments against Hendra virus and Nipah virus

With funding from the United States' National Institutes of Health (NIH), and in collaboration with a research team led by Dr Christopher Broder at the Uniformed Services University of the Health Sciences in Bethesda Maryland, CSIRO Livestock Industries' Australian Animal Health Laboratory (AAHL) in Geelong is attempting to develop treatments against Hendra virus and Nipah virus.

9 Jan 2005

Processes shed light on how DNA recombination mechanisms are related

Peter W. Atkinson, a University of California, Riverside professor of entomology and member of the university’s Institute for Integrative Genome Biology, is part of a team that has linked the movement of small pieces of DNA, known as transposable elements, to a process called V(D)J recombination that produces the genetic diversity responsible for the production of antibodies.

6 Jan 2005

Bio-Rad receives FDA approval for new HIV rapid test

Bio-Rad Laboratories announced today that it recently received approval from the U.S. Food and Drug Administration (FDA) for its new Multispot HIV-1/HIV-2 Rapid Test.

4 Jan 2005

High levels of a blood protein called mannose-binding lectin associated with lower risk of heart attack

High levels of a blood protein called mannose-binding lectin (MBL) are associated with lower risk of heart attack, particularly among diabetics, report Saevardottir and colleagues.

28 Dec 2004

New technique for tracking gene regulators

Finding out where gene-regulator proteins bind to DNA and identifying the genes they regulate just got a step easier thanks to a new technique developed by scientists at the U.S. Department of Energy’s Brookhaven National Laboratory.

28 Dec 2004

Course of injections in childhood might help protect people from heart disease later in life

A course of injections in childhood might help protect people from heart disease later in life. And for those whose arteries are already clogged up, a dose of antibodies could provide immediate benefits. That's the enticing vision raised by animal studies.

26 Dec 2004

Shape of a protein on the surface of pneumonia bacteria helps germs invade the human bloodstream

Scientists at St. Jude Children's Research Hospital have discovered that the shape of a protein on the surface of pneumonia bacteria helps these germs invade the human bloodstream.

23 Dec 2004

Somatic hypermutation (SHM) should prove to be extremely useful in directed protein evolution

Fascinated by the efficient way the human immune system generates a rapid response to create a near-infinite variety of antibodies, researchers have "hijacked" that machinery and used it to evolve a new type of fluorescent protein.

23 Dec 2004

Researchers can now inexpensively program the chemical synthesis of entire genes on a single microchip

Devices the size of a pager now have greater capabilities than computers that once occupied an entire room. Similar advances are being made in the emerging field of synthetic biology at the University of Houston, now allowing researchers to inexpensively program the chemical synthesis of entire genes on a single microchip.

23 Dec 2004

Jumping genes help explain immune system's remarkable ability

A team led by Johns Hopkins scientists has found the first clear evidence that the process behind the human immune system's remarkable ability to recognize and respond to a million different proteins might have originated from a family of genes whose only apparent function is to jump around in genetic material.

22 Dec 2004

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Vaccinating large populations of white-footed mice against the bacterium that causes Lyme disease could help reduce the risk of transmission of the disease to humans, says a study supported by the National Institute of Allergy and Infectious Diseases (NIAID).

14 Dec 2004

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Powerful research tools that speed up vaccine development have led to the start today of human tests for a preventive vaccine against the respiratory disease SARS. The disease killed hundreds of people around the world before it was brought under control in 2003 with aggressive conventional public health measures.

13 Dec 2004

Targeted screening of high-risk groups for genital herpes may prevent disease transmission

Identifying asymptomatic people with genital herpes infection through targeted screening of high-risk groups may prevent disease transmission. However, widespread screening of pregnant women is unlikely to reduce the occurrence of herpes in newborns, according to an article in the January 1 issue of Clinical Infectious Diseases, now available online.

13 Dec 2004

Understanding what causes narcolepsy

Results of a preliminary study in this week’s issue of THE LANCET suggest a step forward in our understanding of the processes behind narcolepsy; there appears to be an underlying autoimmune process for people with a certain genetic profile. Future diagnostic testing of people with this profile should lead to substantial improvements in disease treatment.

13 Dec 2004

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

An international consortium of scientists lead by Dr. James Paulson of The Scripps Research Institute has created a technology that will advance our understanding of the role of complex sugar chains (glycans or carbohydrates) that decorate the surface of cells in the body.

8 Dec 2004

Revlimid clinical data in newly diagnosed multiple myeloma presented

Celgene Corporation announced today that data evaluating clinical results on Revlimid (lenalidomide) as a new therapeutic approach for patients with newly diagnosed multiple myeloma (MM) was presented at the American Society of Hematology 46th Annual Meeting in San Diego.

7 Dec 2004

Antibodies News and Research

Gene transfer used to deliver antibodies to fight Anthrax

Safety established for Vaxin's first flu vaccine in clinical trial

Velcade (bortezomib) phase III clinical trial initiated in patients with newly diagnosed multiple myeloma

Scientists identify a protein that regulates alcohol-withdrawal seizures

Australia attempts to develop treatments against Hendra virus and Nipah virus

Processes shed light on how DNA recombination mechanisms are related

Bio-Rad receives FDA approval for new HIV rapid test

High levels of a blood protein called mannose-binding lectin associated with lower risk of heart attack

New technique for tracking gene regulators

Course of injections in childhood might help protect people from heart disease later in life

Shape of a protein on the surface of pneumonia bacteria helps germs invade the human bloodstream

Somatic hypermutation (SHM) should prove to be extremely useful in directed protein evolution

Researchers can now inexpensively program the chemical synthesis of entire genes on a single microchip

Jumping genes help explain immune system's remarkable ability

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Targeted screening of high-risk groups for genital herpes may prevent disease transmission

Understanding what causes narcolepsy

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

Revlimid clinical data in newly diagnosed multiple myeloma presented

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