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Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Imaxio's pro-immunogenic technology used in tuberculosis vaccine phase I clinical study

Imaxio, a biopharmaceutical company specializing in vaccines and genomics, announces today that IMX313, its proprietary pro-immunogenic technology, has been administered for the first time in humans in a tuberculosis vaccine phase I clinical study. The trial is being conducted by the Jenner Institute at Oxford University, England.

3 Sep 2013

Researchers identify origin of human TB

Tuberculosis remains one of deadliest infectious diseases of humans, killing 50% of individuals when left untreated. Even today, TB causes 1-2 million deaths every year mainly in developing countries. Multidrug-resistance is a growing threat in the fight against the disease.

2 Sep 2013

Researchers pinpoint ways to counter effects of antibiotics-driven depletion of gut-dwelling bacteria

A new study by researchers at the Stanford University School of Medicine could help pinpoint ways to counter the effects of the antibiotics-driven depletion of friendly, gut-dwelling bacteria.

2 Sep 2013

Holistic approach to understand and treat TB

For years, physicians around the world have watched as strain after strain of the deadly bacteria Mycobacterium tuberculosis evolves resistance to drugs.

2 Sep 2013

Researchers find parasitic worms limit effects of autoimmune and other diseases

If the idea of hookworms makes you shudder, consider this: Those pesky intestinal parasites may actually help your body ward off other infections, and perhaps even prevent autoimmune and other diseases.

31 Aug 2013

Researchers develop novel technique and device for rapid pasteurization of eggs

Researchers at the Princeton Plasma Physics Laboratory (PPPL) and the U.S. Department of Agriculture (USDA) have developed a novel technique and device for rapidly pasteurizing eggs in the shell without damaging the delicate egg white. The process could lead to a sharp reduction in illnesses caused by egg-borne salmonella bacteria, a widespread public health concern.

30 Aug 2013

BP and headache drug effectively speeds up treatment of TB

Infectious disease experts at Johns Hopkins have found, in studies in mice, that a drug better known as a treatment for high blood pressure and headaches effectively speeds up treatment of TB when added to the standard, daily antibiotic regimen. Test animals were cured in four months instead of the usual six.

30 Aug 2013

Texas A&M University biologist receives federal grant to study Clostridium difficile

A Texas A&M University biologist has received a federal grant to study the fecal samples of hundreds of people to better understand the gut bacteria Clostridium difficile - the cause of some 14,000 deaths a year in America - and to help lay the basic science foundation to develop drugs to combat its deadly results.

30 Aug 2013

Researchers identify and track strains of antibiotic resistant salmonella

Continuing research on Salmonella may enable researchers to identify and track strains of antibiotic resistant bacteria as they evolve and spread, according to researchers in Penn State's College of Agricultural Sciences.

30 Aug 2013

AARDA study reveals mothers antibodies may cause autism in babies

A new, large-scale study of more than 2,700 mothers of children with autism shows that about one in 10 mothers have antibodies in their bloodstream that react with proteins in the brain of their babies.

29 Aug 2013

Genetic analysis of intestinal bacteria shows Danes have 40% less gut bacteria genes

All people have trillions of bacteria living in their intestines. If you place them on a scale, they weigh around 1.5 kg. Previously, a major part of these 'blind passengers' were unknown, as they are difficult or impossible to grow in laboratories.

29 Aug 2013

Researchers identify novel mechanism that particular superbug uses to fend off antibiotic

Investigators working to stem the spread of antibiotic-resistant bacteria have taken a major step in their efforts to develop new treatments.

29 Aug 2013

New clinical recommendations urge women to maintain periodontal health during pregnancy

When a woman becomes pregnant, she knows it is important to maintain a healthy lifestyle to ensure both the health of herself and the health of her baby. New clinical recommendations from the American Academy of Periodontology and the Eurpean Federation of Periodontology urge pregnant women to maintain periodontal health as well.

29 Aug 2013

Fluoride added to water supplies reduces tooth decay in children

Fluoride is a naturally occurring mineral in water and many foods. In addition, fluoride is intentionally added to the public water supplies, because it has been demonstrated that communities with fluoride added to their water supplies have significantly reduced incidence of tooth decay in children.

28 Aug 2013

TSRI scientists find way to use new DNA-editing technology for DNA sequencing

Scientists at The Scripps Research Institute have found a way to apply a powerful new DNA-editing technology more broadly than ever before.

27 Aug 2013

BARDA Awards Novan $7.8M To Develop Thermal Burns Treatment

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26 Aug 2013

Levels of mercury in Pacific Ocean fish likely to increase in coming decades

University of Michigan researchers and their University of Hawaii colleagues say they've solved the longstanding mystery of how mercury gets into open-ocean fish, and their findings suggest that levels of the toxin in Pacific Ocean fish will likely rise in coming decades.

26 Aug 2013

Compounds found in red wine and green tea can be used as antibacterial coating

A simple kitchen sink experiment helped Northwestern University researchers discover that green tea leaves not only can be used to steep a good cup of tea, but they make an excellent antibacterial coating, too.

23 Aug 2013

Study shows how microbes cooperate with sex hormones to affect immune system

Females can mount more powerful immune responses than males, but the flip side of this enhanced protection against infections is a greater risk for autoimmune disorders. Shedding light on the underlying causes of the gender bias in autoimmune diseases, a study published by Cell Press August 22nd in the journal Immunity reveals that certain gut microbes prevalent in males can help protect them against type 1 diabetes.

23 Aug 2013