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Scientists solve mystery behind what triggers the herpes virus to become active again

The mere mention of the word "herpes" usually conjures negative images and stereotypes, but most people have been infected with some form of the virus. For most, a sore appears, heals and is forgotten, although the virus remains latent just waiting for the right circumstances to come back. Now, the mystery behind what triggers the virus to become active again is closer to being solved thanks to new research published in the Journal of Leukocyte Biology's November 2012 issue.

1 Nov 2012

Eliminating bacteria's DNA, boosting antimicrobial proteins may help prevent recurrent ear infections

Eliminating bacteria's DNA and boosting antimicrobial proteins that already exist may help prevent middle ear infections from reoccurring. These are the findings from a Nationwide Children's Hospital study that examined how an immune defense protein common in the middle ear interacts with a structure meant to protect a colony of bacteria.

31 Oct 2012

Sea water strengthens the body against viruses, low defences, bacteria and pathogens

Sea water therapy is a technique of cellular nutrition backed by more than 100 years of clinical use in hospitals, during which numerous studies have demonstrated its beneficial effects on patients' health.

29 Oct 2012

Cellectis announces successful programming of immune system cells to kill cancer cells

Cellectis, the genome engineering specialist, has announced successfully programming cells from the immune system (T cells) to kill cancer cells. This technological breakthrough was revealed for the first time ever on Saturday, October 27th at the congress of the ESGCT (European Society of Gene & Cell Therapy) in Versailles, outside Paris.

29 Oct 2012

FDA report says pharmacy knew about contamination problems

A federal inspection of a company whose tainted pain medicine has caused one of the worst public health drug disasters since the 1930s found greenish-yellow residue on sterilization equipment, surfaces coated with levels of mold and bacteria that exceeded the company's own environmental limits, and an air-conditioner that was shut off nightly despite the importance of controlling temperature and humidity.

29 Oct 2012

Scientists hope to unravel mystery of how Borrelia burgdorferi causes Lyme disease

Investigators at The University of Texas Health Science Center at Houston (UTHealth) have accelerated the search for the bacterial genes that make the Lyme disease bacterium so invasive and persistent. The discovery could advance the diagnosis and treatment of this disease, which affects an estimated 30,000 Americans each year.

29 Oct 2012

Universal approach to MRSA-prevention in ICU is most effective

Universal decolonization of all patients admitted to intensive care units using chlorhexidine baths and mupirocin treatment for 5 days significantly reduces the risk for infection with methicillin-resistant Staphylococcus aureus , report researchers.

26 Oct 2012

Researchers figure out 3D shape of promising TB drug target

Researchers at Johns Hopkins have figured out the three-dimensional shape of the protein responsible for creating unique bonds within the cell wall of the bacteria that cause tuberculosis. The bonds make the bacteria resistant to currently available drug therapies, contributing to the alarming rise of these super-bacteria throughout the world.

26 Oct 2012

CUMC researchers develop first true mouse model of typhoid infection

Columbia University Medical Center (CUMC) researchers have created the first true mouse model of typhoid infection. The development promises to advance the study of typhoid and the creation of new vaccines against the infection, which remains a major health threat in developing countries.

26 Oct 2012

Artificial CSP proteins reduce S. pneumoniae competence y more than 90%

The bacterium Streptococcus pneumoniae - which can cause pneumonia, meningitis, bacteremia and sepsis - likes to share its antibiotic-defeating weaponry with its neighbors. Individual cells can pass resistance genes to one another through a process called horizontal gene transfer, or by "transformation," the uptake of DNA from the environment.

26 Oct 2012

Durata completes target enrollment in dalbavancin Phase 3 trial for ABSSSI

Durata Therapeutics today announced that it has completed its target enrollment for DISCOVER 2 ("Dalbavancin for Infections of the Skin COmpared to Vancomycin at an Early Response"), the second global, Phase 3 clinical trial of Durata's lead product candidate, dalbavancin, under investigation for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible gram-positive bacteria.

26 Oct 2012

New study finds bacteria cue single-celled choanoflagellates to form colonies

Bacteria have a bad rap as agents of disease, but scientists are increasingly discovering their many benefits, such as maintaining a healthy gut.

25 Oct 2012

Simple tricks to keep mold and dust mites at bay during winter

Spring and summer are not the only seasons that bring misery to those with allergies. The winter months can be brutal for people sensitive to mold spores and dust mites.

25 Oct 2012

New method of oral vaccination could help boost immunity to TB, influenza and C. difficile

Scientists at Royal Holloway, University of London have developed a pioneering new method of oral vaccination which could help boost immunity to TB and influenza, as well as prevent C. difficile for which there is currently no vaccine.

25 Oct 2012

Researchers increase potency of a compound that reactivates antibiotics against MRSA

Researchers from North Carolina State University have increased the potency of a compound that reactivates antibiotics against methicillin-resistant Staphylococcus aureus (MRSA), an antibiotic-resistant form of Staphylococcus that is notoriously difficult to treat. Their improved compound removes the bacteria's antibiotic resistance and allows the antibiotic to once again become effective at normal dosage levels.

23 Oct 2012

Study looks at DNA sequences for receptors in T lymphocytes

Our immune system must be tremendously complex to respond to the unending assault of viruses, bacteria and cancerous cells. One of the mechanisms used by the immune system to cope with the huge variety of possible threats is to randomly combine DNA segments for the production of receptors on lymphocytes - a type of white blood cell.

23 Oct 2012

C. diff infections on the rise among children, elderly

Clostridium difficile infections are becoming more common and more severe in hospitalized children and the elderly, in large part due to greater use of antibiotics, Mayo Clinic researchers report in studies being presented at the American College of Gastroenterology annual meeting.

23 Oct 2012

Thiol peroxidase involved in S. pneumoniae defenses

The Streptococcus pneumoniae bacteria defends itself from high levels of hydrogen peroxide with the help of thiol peroxidase, research shows.

22 Oct 2012

Microgravity and prolonged space flight could give unique advantages to germs

The cabin of a spacecraft halfway to Mars would be the least convenient place -- one cannot say "on earth" -- for a Salmonella or Pneumococcus outbreak, but a wide-ranging new paper suggests that microgravity and prolonged space flight could give unique advantages to germs.

22 Oct 2012

Researchers identify how mosquito's immune system attacks specific infections

Researchers at the Johns Hopkins Bloomberg School of Public Health have determined a new mechanism by which the mosquitoes' immune system can respond with specificity to infections with various pathogens, including the parasite that causes malaria in humans, using one single gene.

20 Oct 2012