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Synthesizing Vernix caseosa

Even after nine months soaking in the womb, a newborn's skin is smooth - unlike an adult's in the bath.

17 Mar 2009

Superbug complicates treatment of infections in cystic fibrosis

The unexpected behaviour of a family of "superbugs" called the Burkholderia cepacia complex (Bcc) could have implications for the treatment of cystic fibrosis (CF) patients.

17 Mar 2009

MRSA study suggests strategy shift needed to develop effective therapeutics

USA300-the major epidemic strain of methicillin-resistant Staphylococcus aureus (MRSA) causing severe infections in the United States during the past decade-inherits its destructiveness directly from a forefather strain of the bacterium called USA500 rather than randomly acquiring harmful genes from other MRSA strains.

17 Mar 2009

FDA looks at nanotechnology for the detection of anthrax

The U.S. Food and Drug Administration has completed a "proof-of-concept" study of a test that quickly and accurately detects the presence of even the smallest amount of the deadly anthrax toxin.

17 Mar 2009

Examining the infinitesimal - new approach to microscopy

A new approach to microscopy is opening up the wonders of the molecular world, allowing researchers to examine organic molecules and delicate crystals as they grow, atom by atom. Dr Andrew Humhpris, co-founder of the original technology and now Chief Technology Officer of Infinitesima, explains how this University spin-out has turned into a leading-edge company.

17 Mar 2009

Ultraviolet light cuts spread of tuberculosis

Ultraviolet lights could reduce the spread of tuberculosis in hospital wards and waiting rooms by 70%, according to a new study, published in PLoS Medicine today.

16 Mar 2009

Houseflies may contribute to the dispersion of drug-resistant bacteria

Researchers at the Johns Hopkins Bloomberg School of Public Health found evidence that houseflies collected near broiler poultry operations may contribute to the dispersion of drug-resistant bacteria and thus increase the potential for human exposure to drug-resistant bacteria.

16 Mar 2009

Drugs throw spanner into the molecular works of enzymes

Drugs that work by blocking the function of a protein from the outside also disrupt the protein's internal workings, according to new research from the University of North Carolina at Chapel Hill.

16 Mar 2009

Immune cells play surprising role in cystic fibrosis lung damage

Immune cells once thought to be innocent bystanders in cystic fibrosis may hold the key to stopping patients' fatal lung disease.

16 Mar 2009

Next generation antibiotic compounds that do not provoke bacterial resistance

Bacterial resistance to antibiotics is one of medicine's most vexing challenges.

15 Mar 2009

New approach to prevent bacterial infections from taking hold

Dr Quinn Parks and colleagues describe how they used enzymes against products of the body's own defence cells to prevent Pseudomonas aeruginosa bacteria from building a protective biofilm which enables them to avoid both the body's immune mechanisms and antibiotics.

15 Mar 2009

Researchers look at genetic dynamics of inbreeding depression

Researchers have taken a first look at the broad genetic changes that accompany reproductive declines in inbred populations.

12 Mar 2009

Cells get two chances, not just one, to fix their mistakes

Cells have two chances to fix the same mistake in their protein-making process instead of just one - a so-called proofreading step - that had previously been identified, according to new research.

12 Mar 2009

Bioinformatics sheds light on evolutionary origin of Rickettsia virulence genes

Scientists from the Virginia Bioinformatics Institute (VBI) at Virginia Tech, the University of Maryland School of Medicine, and the University of Louisville have revealed that genes for a specific type of molecular secretion system in Rickettsia, a structure that is linked in many cases to virulence, have been conserved over many years of evolution.

11 Mar 2009

Space-grown bacteria help explain Salmonella illness

Salmonella bacteria research from two recent NASA space missions discovered key elements of the bacteria's disease-causing potential that hold promise for improving ways to fight food-borne infections on Earth.

11 Mar 2009

Protein structures reveal "big bang" of innovation in evolution

A new study of proteins, the molecular machines that drive all life, also sheds light on the history of living organisms.

11 Mar 2009

Researchers probe mechanisms of infection

A newly discovered receptor in a strain of Escherichia coli might help explain why people often get sicker when they're stressed.

10 Mar 2009

How chemicals present in cranberries prevent urinary tract infections

Chemicals present in cranberries - and not the acidity of cranberry juice, as previously thought - prevent infection-causing bacteria from attaching to the cells that line the urinary tract, as documented in a report published in Journal of Medicinal Food.

10 Mar 2009

How to avoid colon problems

Most adults would rather keep talk about colons behind the bathroom door.It's time to talk, says Kim Turgeon, MD, FACP, gastroenterologist in Internal Medicine at the University of Michigan Health System.

10 Mar 2009

Breakthrough improves effectiveness of tuberculosis vaccine

A breakthrough strategy to improve the effectiveness of the only tuberculosis vaccine approved for humans provided superior protection against the deadly disease in a pre-clinical test, report scientists at The University of Texas Health Science Center at Houston in Nature Medicine 's Advance Online Publication March 1.

8 Mar 2009