Biochemistry News and Research

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NIH honors Utah biochemist with Pioneer Award for dsRNA research

University of Utah biochemist Brenda L. Bass, Ph.D., has dedicated her career to following the path less traveled.

23 Sep 2011

Children of parents with drink problem may consume more alcohol after stressful situations

If either of your parents has a drink problem, there is a greater risk that you will consume more alcohol after stressful situations, reveals current research from the Sahlgrenska Academy, at the University of Gothenburg, Sweden.

21 Sep 2011

MDC researchers determine molecular structure of dynamin

Dr. Katja F-lber and Professor Oliver Daumke, structural biologists at the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch, together with researchers from Freie Universit-t (FU) Berlin, have determined the molecular structure of dynamin, a 'wire-puller' that mediates nutrient uptake into the cell.

21 Sep 2011

Niiki Pharma announces positive data from ongoing trial of novel anti-cancer agent NKP-1339

Niiki Pharma Inc. announced interim results from the ongoing Phase I clinical trial of its lead product, NKP-1339. NKP-1339 is a first-in-class transferrin targeted small molecule that down-regulates GRP78, a key regulator of mis-folded protein processing and a tumor survival factor.

20 Sep 2011

Individuals without ubiquitin ligase Nedd4L more likely to develop CF

Cystic fibrosis (CF), a chronic disease that clogs the lungs and leads to life-threatening lung infections, is caused by a genetic defect in a chloride channel called cystic fibrosis transmembrane conductase regulator.

20 Sep 2011

New UCSB technology can identify cancerous prostate cells

A team of researchers at UC Santa Barbara has developed a breakthrough technology that can be used to discriminate cancerous prostate cells in bodily fluids from those that are healthy.

20 Sep 2011

NovaSterilis awarded patent for novel preparation and sterilization of ‘Green State’ devices

NovaSterilis Inc. has been granted US Patent No 7,988,892. The patent, dated August 2, 2011 is entitled “Preparation and Sterilization of Green State Devices Using a Supercritical Fluid Sterilant.”

19 Sep 2011

Online gamers decipher 3D molecular structure that may help AIDS research

Online gamers have deciphered the structure of an enzyme of an AIDS-like virus that had thwarted scientists for a decade. The exploit was published in the journal, Nature Structural & Molecular Biology, where - exceptionally in scientific publishing - both gamers and researchers are honored as co-authors.

19 Sep 2011

Gamers solve molecular structure of retrovirus enzyme

Gamers have solved the structure of a retrovirus enzyme whose configuration had stumped scientists for more than a decade. The gamers achieved their discovery by playing Foldit, an online game that allows players to collaborate and compete in predicting the structure of protein molecules.

19 Sep 2011

Cornell researchers learn how helicase enzyme works to unzip two strands of DNA

With an eye toward understanding DNA replication, Cornell researchers have learned how a helicase enzyme works to actually unzip the two strands of DNA.

19 Sep 2011

CWRU receives NCI grant to advance treatment of gastrointestinal cancers

The National Cancer Institute has awarded $11.3 million to Case Western Reserve University School of Medicine to establish a center of excellence for research on gastrointestinal cancers.

19 Sep 2011

Case Western Reserve awarded $11.3M to establish gastrointestinal cancer research center

The National Cancer Institute has awarded $11.3 million to Case Western Reserve University School of Medicine to establish a center of excellence for research on gastrointestinal cancers. The funding designates the university as a Specialized Program of Research Excellence (SPORE) in Gastrointestinal (GI) Cancers - recognition extended to just one institution this year.

17 Sep 2011

Study examines effects of carbon nanoparticles on living cells

A study by researchers from the schools of science and medicine at Indiana University-Purdue University Indianapolis examines the effects of carbon nanoparticles (CNPs) on living cells. This work is among the first to study concentrations of these tiny particles that are low enough to mimic the actual exposure of an ordinary individual.

16 Sep 2011

Sanford-Burnham and Scripps Health enter joint translational medicine effort

Scripps Health and Sanford-Burnham Medical Research Institute have formed a collaboration to bridge the gap between laboratory scientists uncovering new approaches for treating cancer and the physicians caring for patients with cancer.

14 Sep 2011

Pure maple syrup may promote a healthy liver

New research conducted at the University of Tokyo suggests that pure maple syrup may promote a healthy liver.

14 Sep 2011

Researchers identify new type of potential anticancer drug

Researchers at Emory University School of Medicine have identified a new type of potential anticancer drug. The compound, named FOBISIN, targets 14-3-3 proteins, important for the runaway growth of cancer cells.

13 Sep 2011

Biochemists reveal interaction between tumor suppressor protein and chaperone

Every cell has thousands of proteins whose activity and lifetime must be regulated to control the cellular life cycle from cell division to cell death. The heat shock protein Hsp90 plays a key role in this process. It is a so-called chaperone, a quality controller, as it were. It monitors and controls the quality and activity of many important signal proteins and helps them take on the right form. When the cell is exposed to high stress levels from heat or a lack of oxygen, Hsp90 is produced in larger quantities to shield its partner proteins from damage.

8 Sep 2011

Consuming walnuts slows development and growth of breast cancer tumors

New findings published in Nutrition and Cancer report that consuming walnuts slowed both the development and growth of breast cancer tumors in mice.

7 Sep 2011

Researchers reveal mechanism behind how cells communicate

Cell communication is essential for the development of any organism. Scientists know that cells have the power to "talk" to one another, sending signals through their membranes in order to "discuss" what kind of cell they will ultimately become - whether a neuron or a hair, bone, or muscle. And because cells continuously multiply, it's easy to imagine a cacophony of communication.

6 Sep 2011

Study describes new class of anti-diabetic compound that targets unique molecular switch

In a joint study, scientists from The Scripps Research Institute and Harvard University's Dana-Farber Cancer Institute have established a new class of anti-diabetic compound that targets a unique molecular switch.

5 Sep 2011