Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

New study identifies 16 additional genetic markers linked to psoriasis

It's one of the most common immune-mediated diseases in the U.S., causing red, patchy and scaly marks on the skin. Yet the 1 to 2 percent of the population who have psoriasis are still left to wonder why.

24 May 2017

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Patients with non-small cell lung cancer (NSCLC) often respond to standard chemotherapy, only to develop drug resistance later, and with fatal consequences.

23 May 2017

WPI research program aims to understand gender differences in neurobiology

Many complicated neurological disorders appear to have a gender bias. Women, for example, are more likely to develop Alzheimer's disease, while men are at greater risk for Parkinson's disease.

17 May 2017

Researchers identify many dangerous strains of TB pathogens

Researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences (VIGG) and the Moscow Institute of Physics and Technology have established a catalog of mutations in 319 virulence genes of mycobacteria that cause tuberculosis.

16 May 2017

Research lays groundwork to develop realistic ‘biomimetic neuroprosthetics’

By applying a novel computer algorithm to mimic how the brain learns, a team of researchers – with the aid of the Comet supercomputer based at the San Diego Supercomputer Center at UC San Diego and the Center's Neuroscience Gateway – has identified and replicated neural circuitry that resembles the way an unimpaired brain controls limb movement.

11 May 2017

Metabolite 'signatures' can accurately distinguish typhoid from other fever-inducing diseases

Researchers have identified a metabolite 'signature' that can accurately distinguish typhoid from other fever-inducing tropical diseases using patient blood samples.

9 May 2017

Researchers develop fast algorithm that provides new insights into protein evolution

Understanding evolution is one of the cornerstones of biology - evolution is, in fact, the sole explanation for life's diversity on our planet.

9 May 2017

Study shows clear benefit from ERAS approaches in abdominal and pelvic surgeries

In a new study, Roswell Park Cancer Institute researchers have demonstrated that an approach shown to improve outcomes for patients receiving colorectal surgery is just as effective in patients requiring many other abdominal and pelvic operations.

5 May 2017

Vitamin A deficiency leads to loss of blood stem cells

Many specialized cells, such as in the skin, gut or blood, have a lifespan of only a few days. Therefore, steady replenishment of these cells is indispensable. They arise from so-called "adult" stem cells that divide continuously.

5 May 2017

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

10x Genomics, a company focused on enabling the mastery of biology by accelerating genomic discovery, today announced publication of an article in the journal Nature of a collaborative research study with researchers at the Stanford University School of Medicine.

From 10x Genomics, Inc. 4 May 2017

New research uncovers role of mysterious molecule in skin cancer

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) at Lake Nona uncovers the modus operandi of a mysterious molecule called SPRIGHTLY that has been previously implicated in colorectal cancer, breast cancer, and melanoma.

3 May 2017

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Invivoscribe® Technologies Inc., a global company with more than 20 years of experience providing clonality and biomarker test solutions for the fields of oncology, personalized molecular diagnostics® and personalized molecular medicine®, today announces the premarket approval of LeukoStrat® CDx FLT3 Mutation Assay.

3 May 2017

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

A new $2.4-million program for graduate students seeking to contribute to breakthrough discoveries in medicine and biology has been established at Penn State University with nearly $1.4 million in funding from the National Library of Medicine of the U.S. National Institutes of Health and more than $1 million from Penn State.

28 Apr 2017

Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

Scientists and physicians at University of California San Diego School of Medicine, working with colleagues at the U.S. Navy Medical Research Center - Biological Defense Research Directorate, Texas A&M University, a San Diego-based biotech and elsewhere, have successfully used an experimental therapy involving bacteriophages -- viruses that target and consume specific strains of bacteria -- to treat a patient near death from a multidrug-resistant bacterium.

25 Apr 2017

Researchers identify new rare genetic variants linked to extreme longevity

The search for the genetic determinants of extreme longevity has been challenging, with the prevalence of centenarians (people older than 100) just one per 5,000 population in developed nations.

25 Apr 2017

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Whole-exome DNA sequencing -- a technology that saves time and money by sequencing only protein-coding regions and not the entire genome -- may routinely miss detecting some genetic variations associated with disease, according to Penn State researchers who have developed new ways to identify such omissions.

24 Apr 2017

$Women at highest genetic risk for fracture benefit most from hormone therapy, study finds$

Bioinformatics News and Research

Further Reading

New study identifies 16 additional genetic markers linked to psoriasis

Study points to new pharmacologic approach to target chemo-resistant lung cancer

WPI research program aims to understand gender differences in neurobiology

Researchers identify many dangerous strains of TB pathogens

Research lays groundwork to develop realistic ‘biomimetic neuroprosthetics’

Metabolite 'signatures' can accurately distinguish typhoid from other fever-inducing diseases

Researchers develop fast algorithm that provides new insights into protein evolution

Study shows clear benefit from ERAS approaches in abdominal and pelvic surgeries

Vitamin A deficiency leads to loss of blood stem cells

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

New research uncovers role of mysterious molecule in skin cancer

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

Researchers identify new rare genetic variants linked to extreme longevity

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

Study paves way to develop noninvasive diagnostic test for colorectal cancer

Study finds depression and SUD to be strongest risk factors for prescription opioid overdose

Human Vaccines Project, VUMC and Illumina team up to decipher genetic underpinnings of immune system

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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