Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9th in the open-access journal PLOS Biology by Kim Hai-Man Chow and colleagues at the Chinese University of Hong Kong.

23 Apr 2024

Researchers aim to use AI for early screening and prognosis of Dry Eye Disease

Dry Eye Disease (DED) is one of the more common eye diseases, affecting up to 30% of the world's population.

23 Apr 2024

Merck introduces Aptegra CHO genetic stability assay for accelerated biosafety testing

Merck, a leading science and technology company, has launched the first all-in-one, validated genetic stability assay of its kind.

23 Apr 2024

Tracking arboviruses by nanopore sequencing of mosquitoes

The technology used to sequence SARS-CoV-2 at record speed early in the COVID-19 pandemic has been successfully tested as a technique to monitor arboviruses and diseases transmitted mainly by mosquitoes.

17 Apr 2024

Novel antibacterial discovery: Umbrella toxin particles secreted by Streptomyces

Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors, especially others of their own species.

17 Apr 2024

Study reveals molecular changes in brain cells with Lewy bodies

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.

16 Apr 2024

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

The University of Texas MD Anderson Cancer Center and CureVac N.V. today announced a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.

16 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.

10 Apr 2024

Baylor study reveals role of newly inherited DNA variants in recessive diseases

You have your mother's eyes and your father's smile, but genetics is much more than just what's on the surface.

10 Apr 2024

Researchers develop first genetic maps for disease-linked DNA repeats

A research team led by the University of California, Irvine has built the first genetic reference maps for short lengths of DNA repeated multiple times which are known to cause more than 50 lethal human diseases, including amyotrophic lateral sclerosis, Huntington's disease and multiple cancers.

5 Apr 2024

New ovarian atlas paves the way for extended fertility and hormone restoration

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

5 Apr 2024

Mental illness does not diminish COVID-19 vaccine effectiveness

A large multi-state electronic health record-based study from the Centers for Disease Control and Prevention's (CDC's) VISION Network has found that COVID-19 vaccines are as effective for adults with anxiety or depression or mood disorders as for individuals without these common diagnoses.

3 Apr 2024