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Unraveling gene regulation's role in pulmonary fibrosis

Regulators of gene expression are thought to play an outsized role in disorders from cancers to heart disease. But how exactly do variations in gene regulation translate into a disease's biology?

28 Mar 2024

Predicting treatment response in common blood cancer with DNA methylation profiling

A recent study led by Dr. Manel Esteller, Director of the Josep Carreras Institute, shows how DNA methylation profiling in a common type of blood cancer, myelodysplastic syndrome, predicts whether the patient will respond to treatment.

28 Mar 2024

Using microbiota analysis for health and disease management

The human body harbors approximately 30 trillion microbes, known collectively as the microbiota.

28 Mar 2024

Study provides a hopeful direction for the management of penile squamous cell carcinoma

In a recent multi-center study published in the Journal of the National Cancer Institute, researchers examined the effects of neoadjuvant chemotherapy (NAC) on patients suffering from locally advanced penile squamous cell carcinoma (PSCC).

28 Mar 2024

Clinical trial to test the feasibility of using at-home cancer immunotherapy

A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.

28 Mar 2024

Familial Alzheimer's transmissible through bone marrow transplants, study shows

Familial Alzheimer's disease can be transferred via bone marrow transplant, researchers show March 28 in the journal Stem Cell Reports.

28 Mar 2024

Researchers discover key drivers behind follicular lymphoma's aggressive transformation

A team led by researchers at Weill Cornell Medicine has identified important drivers of the transformation of a type of blood cancer called follicular lymphoma from a slow-growing form to the aggressive form it takes in some patients.

28 Mar 2024

Cells' built-in stopwatch safeguards mitosis

Each day, hundreds of billions of cells in our body cycle through a period of growth and division. Yet in that time, only about 30 minutes is spent on the critical orchestration of mitosis, when chromosomes are carefully segregated from one parent cell to the next generation of two daughter cells.

28 Mar 2024

Dartmouth research unlocks extended cell death pathway in aging brain cells

For oligodendrocytes-;the central nervous system cells critical for brain function-;age may not bring wisdom, but it does come with the power to cling to life for much, much longer than scientists knew.

28 Mar 2024

Longer durations of breastfeeding lowers the risk of childhood cancers

Whether duration of breastfeeding was associated with a lower risk of childhood cancers.

28 Mar 2024

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer.

27 Mar 2024

Breakthrough tool illuminates neural stem cell dynamics

Researchers can use the light naturally thrown off by biological specimens to better study the different states of stem cells in the nervous system, thanks to a tool developed at the University of Wisconsin–Madison, brightening their chances for studying the way stem cells age.

27 Mar 2024

New treatment paradigm focuses on reverting cancer cells to normal state

St. Jude Children's Research Hospital scientists reversed an aggressive cancer, reverting malignant cells towards a more normal state. Rhabdoid tumors are an aggressive cancer which is missing a key tumor suppressor protein.

27 Mar 2024

DNA damage in neurons crucial for creating stable memories

Just as you can't make an omelet without breaking eggs, scientists at Albert Einstein College of Medicine have found that you can't make long-term memories without DNA damage and brain inflammation. Their surprising findings were published online today in the journal Nature.

27 Mar 2024

Enzymatic cocktail emerges as new hope against mycobacterial infections

With resistance to chemical antibiotics on the rise, the world needs entirely new forms of antibiotics. A new study published in Microbiology Spectrum, a journal of the American Society for Microbiology, shows that an enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.

27 Mar 2024

Breakthrough discovery points to potential treatment for rare neurodegenerative disease

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Cell News and Research

Unraveling gene regulation's role in pulmonary fibrosis

Predicting treatment response in common blood cancer with DNA methylation profiling

Using microbiota analysis for health and disease management

Study provides a hopeful direction for the management of penile squamous cell carcinoma

Clinical trial to test the feasibility of using at-home cancer immunotherapy

Familial Alzheimer's transmissible through bone marrow transplants, study shows

Researchers discover key drivers behind follicular lymphoma's aggressive transformation

Cells' built-in stopwatch safeguards mitosis

Dartmouth research unlocks extended cell death pathway in aging brain cells

Longer durations of breastfeeding lowers the risk of childhood cancers

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

Breakthrough tool illuminates neural stem cell dynamics

New treatment paradigm focuses on reverting cancer cells to normal state

DNA damage in neurons crucial for creating stable memories

Enzymatic cocktail emerges as new hope against mycobacterial infections

Breakthrough discovery points to potential treatment for rare neurodegenerative disease

AI-powered method predicts protein dynamics to accelerate drug discovery

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Exploring the link between prenatal nutrition and congenital craniofacial malformations

New insights into the exacerbation of psoriasis through specific genetic defects

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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