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Merlin and Hippo proteins interact to begin chain of events that control tissue growth

Johns Hopkins researchers have figured out the specific job of a protein long implicated in tumors of the nervous system. Reporting on a new study described in the Sept. 12 issue of the journal Cell, they detail what they call the "matchmaking" activities of a fruit fly protein called Merlin, whose human counterpart, NF2, is a tumor suppressor protein known to cause neurofibromatosis type II when mutated.

12 Sep 2013

Current criteria for ALK positive lung cancer needs to be redefined

A University of Colorado Cancer Center study published today in the journal Cancer shows that the current criteria used to match lung cancers with the drug crizotinib may miss some patients who could benefit from the drug. The findings suggest that doctors should look closer at borderline or atypical ALK-negative cases, and could widen the population of lung cancer patients offered treatment with crizotinib or other ALK-inhibitor drugs.

12 Sep 2013

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

The ability to visualize and analyze the spread of viral infections in primary and metastatic tumors is an essential component in characterizing the therapeutic efficacy of oncolytic viruses.

12 Sep 2013

BioTek's new MultiFlo FX Microplate Dispenser combines dispensing and washing in one platform

BioTek's new MultiFlo FX Microplate Dispenser offers up to four independent reagent dispensers and a washer in one compact and modular platform to simplify and automate microplate-based liquid handling processes, thus saving time and reducing reagent costs.

12 Sep 2013

BioTek's BioStack 4 Microplate Stacker provides walk-away automation for routine microplate processes

BioTek introduces the BioStack 4 Microplate Stacker, providing walk-away automation for routine microplate-based processes including cell-based assays and any application requiring automated plate delidding and re-lidding.

12 Sep 2013

BioTek's Cytation3 Cell Imaging Multi-Mode Reader recognized by SelectScience

For the second year in a row, BioTek Instruments was announced as winner of the SelectScience "Scientists' Choice Award for Best Drug Discovery Product". The award was given for BioTek's new Cytation3 Cell Imaging Multi-Mode Reader, and was announced at ELRIG Drug Discovery in Manchester, UK.

12 Sep 2013

Asthma experts united to tackle Europe's high asthma prevalence and death rates

Asthma experts from across Europe are uniting as part of a new partnership launched this week to tackle Europe's high asthma prevalence and death rates.

12 Sep 2013

Protein plays important role in process of degradation of tumour cells, say researchers

When tumour cells no longer degrade themselves, cancer may develop. Using black skin cancer as an example, Bern Researchers have now shown that a protein plays an important role in the process of degradation of tumour cells. By reactivating this degradation therapeutically, you can virtually force tumours to digest themselves.

12 Sep 2013

Scientists reveal how organic mercury can interfere with vision

More than one billion people worldwide rely on fish as an important source of animal protein, states the United Nations Food and Agriculture Organization. And while fish provide slightly over 7 per cent of animal protein in North America, in Asia they represent about 23 per cent of consumption.

12 Sep 2013

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

Whether it's the Ebola virus or Sarin and Ricin, a key to responding to chemical or biological attacks is having effective antidotes at the ready. To accelerate the development of new therapies, Wake Forest Baptist Medical Center's Institute for Regenerative Medicine is leading a unique $24 million federally funded project to develop a "body on a chip" that will be used to develop these countermeasures.

12 Sep 2013

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

Amgen today announced the publication of a biomarker analysis of Vectibix (panitumumab) in combination with FOLFOX, a type of oxaliplatin-based chemotherapy, for the first-line treatment of patients with metastatic colorectal cancer.

12 Sep 2013

arGEN-X generates potent antibody antagonists of Nav1.7 using SIMPLE Antibody technology

arGEN-X, a clinical stage human monoclonal antibody therapeutics company, announces it has successfully generated potent antibody antagonists of Nav1.7, using its proprietary SIMPLE Antibody™ technology.

12 Sep 2013

Dartmouth researchers find that protein cyclin A plays important role in cell division process

In a study to be published in the journal Nature, two Dartmouth researchers have found that the protein cyclin A plays an important but previously unknown role in the cell division process, acting as a master controller to ensure the faithful segregation of chromosomes during cell division.

12 Sep 2013

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

A family of microRNAs (miR-200) blocks cancer progression and metastasis by stifling a tumor's ability to weave new blood vessels to support itself, researchers at The University of Texas MD Anderson Cancer Center report today in Nature Communications.

12 Sep 2013

New HIV/AIDS vaccine candidate appears to clear AIDS-causing virus from body

An HIV/AIDS vaccine candidate developed by researchers at Oregon Health & Science University appears to have the ability to completely clear an AIDS-causing virus from the body.

12 Sep 2013

Exposing young girls to ionizing radiation can raise risk of breast cancer later in life

Exposing young women and girls under the age of 20 to ionizing radiation can substantially raise the risk of their developing breast cancer later in life. Scientists may now know why. A collaborative study, in which Berkeley Lab researchers played a pivotal role, points to increased stem cell self-renewal and subsequent mammary stem cell enrichment as the culprits.

12 Sep 2013

Research: New pathway plays role in fighting gut infection

The researchers found virulent E. coli bacteria blocked a pathway that would normally protect the gut from infection. These infections are particularly serious in young children and can result in diarrhoea and other complications such as kidney damage.

12 Sep 2013

New research explains how DNA strands repair themselves

Researchers have discovered the details of how cells repair breaks in both strands of their DNA, a potentially devastating kind of DNA damage.

12 Sep 2013

Antioxidant substances in red wine, dark chocolate, olive oil linked with health benefits

The scientific spotlight focuses today on the healthful antioxidant substances in red wine, dark chocolate, olive oil, coffee, tea, and other foods and dietary supplements that are enticing millions of consumers with the promise of a healthier, longer life.

12 Sep 2013

Study shows fat transplantation may treat inherited metabolic diseases

Transplanting fat may treat such inherited metabolic diseases as maple syrup urine disease (MSUD) by helping the body process the essential amino acids that these patients cannot, according to Penn State College of Medicine researchers.

12 Sep 2013

Cell News and Research

Merlin and Hippo proteins interact to begin chain of events that control tissue growth

Current criteria for ALK positive lung cancer needs to be redefined

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

BioTek's new MultiFlo FX Microplate Dispenser combines dispensing and washing in one platform

BioTek's BioStack 4 Microplate Stacker provides walk-away automation for routine microplate processes

BioTek's Cytation3 Cell Imaging Multi-Mode Reader recognized by SelectScience

Asthma experts united to tackle Europe's high asthma prevalence and death rates

Protein plays important role in process of degradation of tumour cells, say researchers

Scientists reveal how organic mercury can interfere with vision

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

arGEN-X generates potent antibody antagonists of Nav1.7 using SIMPLE Antibody technology

Dartmouth researchers find that protein cyclin A plays important role in cell division process

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

New HIV/AIDS vaccine candidate appears to clear AIDS-causing virus from body

Exposing young girls to ionizing radiation can raise risk of breast cancer later in life

Research: New pathway plays role in fighting gut infection

New research explains how DNA strands repair themselves

Antioxidant substances in red wine, dark chocolate, olive oil linked with health benefits

Study shows fat transplantation may treat inherited metabolic diseases

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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