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Study on how Hedgehog signal defines cell-cell interaction receives $747,000 grant

While many researchers believe that the Hedgehog (Hh) signaling pathway, which transmits information to embryonic cells for proper development and is important for regeneration, may actually regulate cell-cell adhesion and segregation - there isn't any evidence.

16 Mar 2013

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies.

16 Mar 2013

Abiraterone's anti-androgenic properties may stop tumor growth of CRPC, says prize-winning Dutch study

As part of an EU-supported IMI-PREDECT consortium, a Dutch study showed that anti-androgenic properties of the drug abiraterone may provide an additional mechanism of action in blocking tumour growth of castration resistant prostate cancer (CRPC).

16 Mar 2013

Researchers identifiy elusive anti-cancer property of vitamin E

Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find. Many animal studies have suggested that vitamin E could prevent cancer, but human clinical trials following up on those findings have not shown the same benefits.

16 Mar 2013

Alzheimer's research demonstrates cell-to-cell transmission of neurodegenerative proteins

Injecting synthetic tau fibrils into animal models induces Alzheimer's-like tau tangles and imitates the spread of tau pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania being presented at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013.

16 Mar 2013

Study: Flagellin plays a critical role in regulating host innate defences against UTIs

A new study by British scientists reveals that motile Escherichia coli isolates demonstrated significant activation of NF-κB signaling suggesting that flagellin plays a key role in up-regulating the host innate defences against urinary tract infections (UTIs).

15 Mar 2013

Expert offers eight tips to help avert winter slips and falls

We all followed the "spring forward" adage as daylight savings time began but due to icy, wintery conditions, many have continued to "spring forward" due to tumbles on the ice.

15 Mar 2013

Previously unknown cell discovered in the urethra of mice

A recent study conducted by a group of German scientists revealed the presence of a previously unknown cell in the urethra of mice. These chemosensory cholinergic brush cells are in close contact to sensory neurons that express cholinergic receptors.

15 Mar 2013

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific for proteins on the outside of the virus, specifically the hemagglutinin protein.

15 Mar 2013

Brown fat cells protective against obesity and diabetes

Brown fat is a hot topic, pardon the pun. Brown fats cells, as opposed to white fat cells, make heat for the body, and are thought to have evolved to help mammals cope with the cold. But, their role in generating warmth might also be applied to coping with obesity and diabetes.

15 Mar 2013

New hunt for intrinsic mechanism linked to schizophrenia

Since the 1960s, psychiatrists have been hunting for substances made by the body that might accumulate in abnormally high levels to produce the symptoms associated with schizophrenia. In particular, there was a search for chemicals that might be related to the hallucinogens phencyclidine (PCP) or lysergic acid diethylamide (LSD), which could explain the emergence of psychotic symptoms in schizophrenia.

15 Mar 2013

Researchers show inhibiting brain's filter can boost performance for tasks

The brain's prefrontal cortex is thought to be the seat of cognitive control, working as a kind of filter that keeps irrelevant thoughts, perceptions and memories from interfering with a task at hand.

15 Mar 2013

Researchers identify enzymes that activate coronavirus for infection

Scientists all over the world are on a quest for an antidote since the first patient died from the new coronavirus in summer 2012. Infection Researchers from the German Primate Center have now identified enzymes that activate the virus for infection.

15 Mar 2013

New therapeutic approach for bladder pain syndrome

Severe chronic pain associated with conditions such as bladder pain syndrome/interstitial cystitis often require the use of opioid medication, with the risk of dependency and serious adverse reactions.

15 Mar 2013

Max Planck Florida Institute for Neuroscience gets grant for research into neurological disorders

The Max Planck Florida Institute for Neuroscience, the first and only U.S. extension of the prestigious Max Planck Society, today announced it has received approximately $1,257,500 in grant funding from prestigious national and international organizations to fund research into Parkinson-s, epilepsy and other neurological disorders.

15 Mar 2013

Study identifies genetic cause of developmental delay in Amish individuals in USA

Researchers from the research group in growth factors and cell differentiation at the University of Barcelona (UB) and the IDIBELL and have participated in an international study that has identified the genetic cause of developmental delay observed in Amish individuals in the USA.

15 Mar 2013

Results from GTx's Phase 2 clinical trial of enobosarm published online

GTx, Inc. today announced that the journal, The Lancet Oncology, has published online ahead of its April print edition the results from GTx's randomized, double-blind, placebo-controlled Phase 2 clinical trial of enobosarm to assess its effects on muscle wasting and physical function in patients with cancer.

15 Mar 2013

Research shows THz pulses destroy skin tissue and increase tumor-suppressing proteins

Terahertz (THz) radiation, a slice of the electromagnetic spectrum that occupies the middle ground between microwaves and infrared light, is rapidly finding important uses in medical diagnostics, security, and scientific research. As scientists and engineers find evermore practical uses for this form of radiation, questions persist about its potential human health risks.

15 Mar 2013

Phase 1b study of olesoxime initiated in multiple sclerosis (MS) patients

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14 Mar 2013

VCP gene mutations cause neurological conditions including IBMPFD and ALS

New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone and Frontotemporal Dementia (IBMPFD), and the motor neuron disease Amyotrophic Lateral Sclerosis (ALS).

14 Mar 2013

Cell News and Research

Study on how Hedgehog signal defines cell-cell interaction receives $747,000 grant

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Abiraterone's anti-androgenic properties may stop tumor growth of CRPC, says prize-winning Dutch study

Researchers identifiy elusive anti-cancer property of vitamin E

Alzheimer's research demonstrates cell-to-cell transmission of neurodegenerative proteins

Study: Flagellin plays a critical role in regulating host innate defences against UTIs

Expert offers eight tips to help avert winter slips and falls

Previously unknown cell discovered in the urethra of mice

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Brown fat cells protective against obesity and diabetes

New hunt for intrinsic mechanism linked to schizophrenia

Researchers show inhibiting brain's filter can boost performance for tasks

Researchers identify enzymes that activate coronavirus for infection

New therapeutic approach for bladder pain syndrome

Max Planck Florida Institute for Neuroscience gets grant for research into neurological disorders

Study identifies genetic cause of developmental delay in Amish individuals in USA

Results from GTx's Phase 2 clinical trial of enobosarm published online

Research shows THz pulses destroy skin tissue and increase tumor-suppressing proteins

Phase 1b study of olesoxime initiated in multiple sclerosis (MS) patients

VCP gene mutations cause neurological conditions including IBMPFD and ALS

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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