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Parents of sickle cell babies undercounseled

Parents of newborns with the sickle cell anemia trait are significantly less likely to receive genetic counseling than those of babies who are cystic fibrosis carriers, say researchers.

17 Sep 2012

Refinements in gene therapy prove beneficial for ‘bubble babies’

Results from a long-term study published in Blood show that adding a low dose of chemotherapy prior to gene therapy can help improve outcomes in children with adenosine deaminase-deficient severe combined immunodeficiency.

17 Sep 2012

Single HPV protein is required for cervical cancer growths to survive

Human papillomavirus (HPV) has long been implicated in cervical cancer, but details of how it happens have remained a mystery. Now researchers at the University of Wisconsin-Madison have found that a single HPV protein is required for cervical cancer and even pre-cancer growths in the cervix to survive.

17 Sep 2012

NIH awards ASC grant to study ASC-101-treated amniotic fluid-derived stem cells in compartment syndrome

America Stem Cell, Inc. today announced that it has been awarded an Advanced Technology Small Business Technology Transfer Research (STTR) grant from the National Heart Lung and Blood Institute at the National Institutes of Health.

17 Sep 2012

Researchers identify gene mutations in Wolfram syndrome that affects insulin-secreting beta cells

The rare disorder Wolfram syndrome is caused by mutations in a single gene, but its effects on the body are far reaching. The disease leads to diabetes, hearing and vision loss, nerve cell damage that causes motor difficulties, and early death.

17 Sep 2012

Natural antibiotic to treat tuberculosis

A natural product secreted by a soil bacterium shows promise as a new drug to treat tuberculosis report scientists in a new study published in EMBO Molecular Medicine. A team of scientists working in Switzerland has shown how pyridomycin, a natural antibiotic produced by the bacterium Dactylosporangium fulvum, works.

17 Sep 2012

Novel drug combination for patients with NRAS-mutant melanoma

A new study published online in Nature Medicine, led by scientists at The University of Texas MD Anderson Cancer Center, describes the discovery of a novel drug combination aimed at a subset of melanoma patients who currently have no effective therapeutic options.

17 Sep 2012

Progenra’s P5091 inhibits growth of bortezomib resistant multiple myeloma tumor cells

Researchers at the Dana-Farber Cancer Institute and Progenra, Inc. announce the publication of a research article entitled "A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance."

17 Sep 2012

PARP inhibitors may be novel treatment strategy in women with HER2-positive breast cancers

Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive breast cancers, according to the results of a study published in Cancer Research, a journal of the American Association for Cancer Research.

17 Sep 2012

Breath testing could discriminate between benign and malignant pulmonary nodules

A pilot study, published in the October 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed that breath testing could be used to discriminate between benign and malignant pulmonary nodules.

17 Sep 2012

Scientists describe how natural selection occurs at the cellular level

Scientists from the Spanish National Cancer Research Centre (CNIO) describe how natural selection also occurs at the cellular level, and how our body's tissues and organs strive to retain the best cells in their ranks in order to fend off disease processes.

15 Sep 2012

Study could reveal whether breast cancer patients with BRCA mutations are responsive to Veliparib

Ongoing research at the Methodist Cancer Center could reveal whether metastatic breast cancer patients with BRCA gene mutations are particularly responsive to a drug regimen that includes Veliparib, an investigational drug believed to hamper cancer cells.

15 Sep 2012

Popular Science magazine names UCLA professor among ‘Brilliant 10’

Popular Science magazine has named Aydogan Ozcan, an associate professor of electrical engineering and bioengineering at UCLA, one of the world's "Brilliant 10" scientists in its October 2012 issue.

15 Sep 2012

New stem cell differentiation study could help scientists better understand genetic basis of CVD

The fate of an embryonic stem cell, which has the potential to become any type of body cell, is determined by a complex interaction of genes, proteins that bind DNA, and molecules that modify those genes and proteins.

15 Sep 2012

Allele’s scientists describe important advance in generation of human stem cells

This week in the journal Scientific Reports, scientists from Allele Biotechnology describe an important advance in the generation of stem cells capable of producing all the different tissues of the human body.

15 Sep 2012

Brandeis University biology professor receives NIH Director's New Innovator award

Chances are you didn't spend much time this morning getting your shoes on or thinking about which route you would take to work. But for people suffering with debilitating diseases such as ALS (Lou Gehrig's disease) or Alzheimer's, such simple functions -- and even activities like breathing and eating -- can be a struggle.

15 Sep 2012

Pancreatic B-cell dedifferentiation leads to decline in insulin production in type 2 diabetes

Scientists generally think that reduced insulin production by the pancreas, a hallmark of type 2 diabetes, is due to the death of the organ's beta cells. However, a new study by Columbia University Medical Center (CUMC) researchers shows that beta cells do not die but instead revert to a more fundamental, undifferentiated cell type.

15 Sep 2012

Sanford-Burnham scientist to receive NIH’s New Innovator Award

The National Institutes of Health (NIH) Office of the Director today announced that Duc Dong, Ph.D., assistant professor at Sanford-Burnham Medical Research Institute (Sanford-Burnham), will receive a New Innovator Award.

15 Sep 2012

UMDNJ, Proteonomix to conduct UMK-121 Phase 1 trial in end-stage liver disease

Proteonomix, Inc., a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives, today announced it has entered into an agreement with Piscataway, N.J.-based University of Medicine and Dentistry of New Jersey (UMDNJ) to conducted a Phase 1 clinical trial with its proprietary, patent-pending mobilization technology UMK-121 in patients with end-stage liver disease (ESLD).

15 Sep 2012

A mysterious form of cell death uncovers prime suspect for new cancer drug development

A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.

15 Sep 2012

Cell News and Research

Parents of sickle cell babies undercounseled

Refinements in gene therapy prove beneficial for ‘bubble babies’

Single HPV protein is required for cervical cancer growths to survive

NIH awards ASC grant to study ASC-101-treated amniotic fluid-derived stem cells in compartment syndrome

Researchers identify gene mutations in Wolfram syndrome that affects insulin-secreting beta cells

Natural antibiotic to treat tuberculosis

Novel drug combination for patients with NRAS-mutant melanoma

Progenra’s P5091 inhibits growth of bortezomib resistant multiple myeloma tumor cells

PARP inhibitors may be novel treatment strategy in women with HER2-positive breast cancers

Breath testing could discriminate between benign and malignant pulmonary nodules

Scientists describe how natural selection occurs at the cellular level

Study could reveal whether breast cancer patients with BRCA mutations are responsive to Veliparib

Popular Science magazine names UCLA professor among ‘Brilliant 10’

New stem cell differentiation study could help scientists better understand genetic basis of CVD

Allele’s scientists describe important advance in generation of human stem cells

Brandeis University biology professor receives NIH Director's New Innovator award

Pancreatic B-cell dedifferentiation leads to decline in insulin production in type 2 diabetes

Sanford-Burnham scientist to receive NIH’s New Innovator Award

UMDNJ, Proteonomix to conduct UMK-121 Phase 1 trial in end-stage liver disease

A mysterious form of cell death uncovers prime suspect for new cancer drug development

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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