Cell News and Research

RSS

Adding bavituximab to docetaxel doubles overall survival in late-stage NS-NSCLC patients

Adding the monoclonal antibody bavituximab to docetaxel chemotherapy doubles overall response rate and improves progression-free survival and overall survival in late-stage non-squamous, non-small cell lung cancer (NS-NSCLC) patients who have already received one prior chemotherapy regimen, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.

7 Sep 2012

Married patients with locally advanced lung cancer likely to survive longer after treatment

Married patients with locally advanced lung cancer are likely to survive longer after treatment than patients who are single, according to a study by researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center in Baltimore.

7 Sep 2012

PCI after lung cancer treatment reduces risk of brain metastases in stage III NSCLC patients

Stage III non-small cell lung cancer (NSCLC) patients treated with surgery and/or radiation therapy have a significantly reduced risk of developing brain metastases if they also receive prophylactic cranial irradiation (PCI); however, this study did not show an improvement in overall survival with PCI, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.

7 Sep 2012

Study investigates effects of acidity on breast and pancreatic cancer cell lines

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment.

7 Sep 2012

Crizotinib effective in shrinking tumors in patients with ALK positive non-small cell lung cancer

Crizotinib is effective in shrinking tumors in patients with anaplastic lymphoma receptor tyrosine kinase (ALK) positive non-small cell lung cancer, a cancer commonly found in people who never smoked, and should be the standard of care for advanced stages of this disease, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.

7 Sep 2012

Race, marital status can impact survival rates of patients with Stage III non-small cell lung cancer

A study of survival data for Stage III, non-small cell lung cancer (NSCLC) patients at the University of Maryland's Greenebaum Cancer Center in Baltimore indicates that marital status and race can significantly impact patient survival rates, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.

7 Sep 2012

OncoMed announces data from demcizumab preclinical study on pancreatic cancer

OncoMed Pharmaceuticals, Inc., a clinical-stage company developing novel therapeutics that target cancer, today announced the online publication in Clinical Cancer Research of preclinical data demonstrating the potent anti-cancer activity of anti-DLL4 (demcizumab) in patient-derived pancreatic tumor models.

7 Sep 2012

Q Therapeutics licenses Neuralstem's Spinal Cord Delivery Platform and Floating Cannula

Neuralstem, Inc. announced that it has granted the first licenses for use of its Spinal Cord Delivery Platform and Floating Cannula, for delivering therapeutic agents to the spinal cord, to Salt Lake City-based Q Therapeutics.

7 Sep 2012

DNA synthesis methods: an interview with Clemens Richert

Automated DNA synthesis has been around for almost three decades. The key difference between the established methodology for making oligodeoxynucleotides (short stretches of single-stranded DNA) and our method is the template strand.

7 Sep 2012

RSV virus selectively kills cancer cells

RSV, a virus that causes respiratory infections in infants and young children, selectively kills cancer cells while leaving healthy cells alone, researchers from the School of Medicine at The University of Texas Health Science Center San Antonio said.

7 Sep 2012

Lack of Atoh1 master gene can lead to sudden infant death syndrome

When mice are born lacking the master gene Atoh1, none breathe well and all die in the newborn period. Why and how this occurs could provide new answers about sudden infant death syndrome (SIDS), but the solution has remained elusive until now.

7 Sep 2012

GENCODE Consortium uncovers staggering array of genes in human genome

The GENCODE Consortium expects the human genome has twice as many genes than previously thought, many of which might have a role in cellular control and could be important in human disease. This remarkable discovery comes from the GENCODE Consortium, which has done a painstaking and skilled review of available data on gene activity.

7 Sep 2012

Book examines highly complex structures of synaptic regions

Synapses are bulbous structures where two neurons communicate. Neurotransmitter molecules released from the presynaptic terminal of one neuron diffuse to the postsynaptic terminal on the other, binding to receptors that lead to propagation or modulation of the signal.

7 Sep 2012

Interleukin-18 plays a key role in inflammation

The naturally occurring cytokine interleukin-18, or IL-18, plays a key role in inflammation and has been implicated in serious inflammatory diseases for which the prognosis is poor and there are currently limited treatment options.

7 Sep 2012

Absence of Puma and Bim protein leads to autoimmune diseases

Researchers at the Walter and Eliza Hall Institute have discovered that a pair of molecules work together to kill so-called 'self-reactive' immune cells that are programmed to attack the body's own organs.

7 Sep 2012

Study finds PARP1 and EZH2 as potential therapeutic targets for small cell lung cancer

Newly discovered molecular differences between small cell lung cancer and nonsmall cell lung cancer have revealed PARP1 and EZH2 as potential therapeutic targets for patients with small cell lung cancer, according to the results of a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

7 Sep 2012

Cell News and Research

Adding bavituximab to docetaxel doubles overall survival in late-stage NS-NSCLC patients

Married patients with locally advanced lung cancer likely to survive longer after treatment

PCI after lung cancer treatment reduces risk of brain metastases in stage III NSCLC patients

Study investigates effects of acidity on breast and pancreatic cancer cell lines

Crizotinib effective in shrinking tumors in patients with ALK positive non-small cell lung cancer

Race, marital status can impact survival rates of patients with Stage III non-small cell lung cancer

OncoMed announces data from demcizumab preclinical study on pancreatic cancer

Q Therapeutics licenses Neuralstem's Spinal Cord Delivery Platform and Floating Cannula

DNA synthesis methods: an interview with Clemens Richert

RSV virus selectively kills cancer cells

Lack of Atoh1 master gene can lead to sudden infant death syndrome

GENCODE Consortium uncovers staggering array of genes in human genome

Book examines highly complex structures of synaptic regions

Interleukin-18 plays a key role in inflammation

Absence of Puma and Bim protein leads to autoimmune diseases

Study finds PARP1 and EZH2 as potential therapeutic targets for small cell lung cancer

Wnt5a protein essential in repairing the intestine's inner lining

Researchers turn skin cells into embryonic Sertoli-like cells

Clathrin protein plays a key role in cell division

Reduced NF-κB expression linκed to postradiation oral mucosa vulnerability

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest Life Science News