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Roundup: HIV staff to be cut in Ga.; Abortion news in N.J., Mo.; Wis. Medicaid coverage in limbo

A loss of $3.7 million in federal funds is forcing Georgia to reduce its workforce for HIV prevention. After an inquiry by Georgia Health News, the Department of Public Health this week acknowledged that 20 people in state health districts have been notified they will probably lose their jobs in January, and that an unspecified number of staffers at the department level have received the same notification.

23 Dec 2011

Genetic analysis revises treatment recommendations related to thyroid cancer

Cleveland Clinic researchers have discovered three genes that increase the risk of thyroid cancer, which is has the largest incidence increase in cancers among both men and women.

23 Dec 2011

Tyrosine kinases play greater role in mitochondria than previously recognized

Cancer cells tend to take up more glucose than healthy cells, and researchers are increasingly interested in exploiting this tendency with drugs that target cancer cells' altered metabolism.

From Cell Signaling Technology 23 Dec 2011

Potential new strategy against bacteria with multi-drug resistant organisms

Vaccines with broader reach might be made by stimulating specialized immune cells to recognize foreign cell membrane proteins that are shared across bacterial species, say researchers from Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine in a report published online today in Immunity.

23 Dec 2011

Researchers discover key interaction at heart of promising new treatment for Fabry disease

A research team led by biochemist Scott Garman at the University of Massachusetts Amherst has discovered a key interaction at the heart of a promising new treatment for a rare childhood metabolic disorder known as Fabry disease.

23 Dec 2011

Toddlers don't respond to their own voice

When grown-ups and kids speak, they listen to the sound of their voice and make corrections based on that auditory feedback. But new evidence shows that toddlers don't respond to their own voice in quite the same way, according to a report published online on December 22 in Current Biology, a Cell Press publication.

23 Dec 2011

Correcting anemia can preserve kidney function in many transplant recipients

Correcting anemia, a red blood cell deficiency, can preserve kidney function in many kidney transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

23 Dec 2011

LincRNAs play key roles during embryonic brain development

Whitehead Institute scientists have identified conserved, long intervening non-coding RNAs (lincRNAs) that play key roles during embryonic brain development in zebrafish. They also show that the human versions of the lincRNAs can substitute for the zebrafish versions, which implies that the functions of these non-coding RNAs have been retained in humans as well as fish.

23 Dec 2011

UCF scientists pioneer new source of stem cell generation

A process that prompts a single gene to generate millions of supercharged stem cells, which can then turn into any kind of cell a body needs to repair itself, has been patented at the University of Central Florida.

23 Dec 2011

Researchers reveal what cells respond to anesthesia in C. elegans

Physicians use inhalation anesthetics in a way that is incredibly safe for patients, but very little is known about the intricacies of how these drugs actually work in children and adults. Now, researchers have uncovered what cells respond to anesthesia in an organism known as the C. elegans, according to a new study from the Seattle Children's Research Institute. C. elegans is a transparent roundworm used often in research.

23 Dec 2011

Scientists discover how DNA mismatch repair proteins work

In eukaryotes - the group of organisms that include humans - a key to survival is the ability of certain proteins to quickly and accurately repair genetic errors that occur when DNA is replicated to make new cells.

23 Dec 2011

Researchers present results from 31 major studies of blood-related cancers at ASH 2011 meeting

Researchers from the John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 best hospitals for cancer, presented results from 31 major studies of blood-related cancers - leukemia, lymphoma and multiple myeloma -- during the American Society of Hematology (ASH) Annual Meeting, December 10-13, 2011 in San Diego.

23 Dec 2011

Researchers evaluate role of Mediterranean diet ingredients in prevention of cell damage

The researchers evaluated the role of Mediterranean diet ingredients in the prevention and mitigation of cell damage.

23 Dec 2011

Faulty lipid metabolism may cause MS, says forensic anthropologist

An article to be published in the December 2011 issue of The Quarterly Review of Biology argues that multiple sclerosis, long viewed as primarily an autoimmune disease, is not actually a disease of the immune system.

23 Dec 2011

Fluoride has dramatic effects on bacteria inside the mouth

Regular use of fluoride-containing toothpaste and mouthwash has long been known to strengthen the enamel on teeth. But new research by Howard Hughes Medical Institute (HHMI) scientists finds that fluoride also has dramatic effects on bacteria inside the mouth -- including those that form plaque and can cause cavities.

23 Dec 2011

Scientists discover mechanism by which TNFα stimulates tumor formation

An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer formation via the NOTCH signaling pathway, a team of researchers led by scientists at The University of Texas MD Anderson Cancer Center reports today in Molecular Cell.

23 Dec 2011

Gladstone, Bristol-Myers Squibb to identify and validate novel targets in Alzheimer's

Bristol-Myers Squibb Company and the Gladstone Institutes today announced the formation of a discovery-based research collaboration to identify and validate novel targets in Alzheimer's disease.

23 Dec 2011

First picture of how specialized neurons are organized in hairy skin

Compared to our other senses, scientists don't know much about how our skin is wired for the sensation of touch. Now, research reported in the December 23rd issue of the journal Cell, a Cell Press publication, provides the first picture of how specialized neurons feel light touches, like a brush of movement or a vibration, are organized in hairy skin.

23 Dec 2011

ViroPharma to acquire Meritage

ViroPharma Incorporated today announced that it has entered into an exclusive option to acquire Meritage Pharma, Inc., a private company based in San Diego, CA focused on developing oral budesonide suspension (OBS) as a treatment for eosinophilic esophagitis (EoE), a chronic inflammatory disorder of the esophagus.

23 Dec 2011

Researchers identify molecules that can stimulate heart muscle regeneration

Damaged heart tissue is not known for having much inherent capacity for repair. But now, scientists are closing in on signals that may be able to coax the heart into producing replacement cardiac muscle cells. Using a zebrafish model system, researchers have identified a family of molecules that can stimulate stem cells to develop into beating heart muscle cells.

23 Dec 2011