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Biomarker can help identify GVHD in cancer patients after hematopoietic stem cell transplant

A University of Michigan Health System-led team of researchers has found a biomarker they believe can help rapidly identify one of the most serious complications in patients with leukemia, lymphoma and other blood disorders who have received a transplant of new, blood-forming cells.

22 Oct 2011

SCP acts as an important inhibitor of cancer cell migration and growth

A revolutionary discovery regarding motile cancer cells made by research scientists at VTT Technical Research Centre of Finland and the University of Turku is challenging previous conceptions.

22 Oct 2011

Researchers identify cancer cell cycle-regulated mechanism

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells.

22 Oct 2011

Romark announces results from NT-300 Phase 2B-3 trial on influenza

Romark Laboratories announced that results of a large Phase 2B-3 US clinical trial of its new flu drug, NT-300 (nitazoxanide), will be presented as an oral late-breaking communication at the 49th Annual Meeting of the Infectious Diseases Society of America (IDSA) being held in Boston, October 20-23, 2011.

22 Oct 2011

Two proteins bind together to ignite and sustain malignant brain tumors

Two previously unassociated proteins known to be overly active in a variety of cancers bind together to ignite and sustain malignant brain tumors, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports this week in the journal Cancer Cell.

22 Oct 2011

Xencor commences XmAb5871 Phase 1 trial in autoimmune diseases

Xencor, Inc., a company using its proprietary Protein Design Automation (PDA) platform technology to engineer next-generation antibodies, announced today the initiation of a Phase 1 clinical trial of XmAb5871, the company's therapeutic antibody for the treatment of autoimmune diseases.

22 Oct 2011

Allos terminates AMAG merger agreement with AMAG

Allos Therapeutics, Inc. announced today that the Agreement and Plan of Merger and Reorganization entered into by and among Allos, AMAG and Alamo Acquisition Sub, Inc. on July 19, 2011, as amended on August 8, 2011, has been terminated.

22 Oct 2011

Wolbachia study reveals novel approaches to control insects transmitting deadly diseases

Researchers at Boston University have made discoveries that provide the foundation towards novel approaches to control insects that transmit deadly diseases such as dengue fever and malaria through their study of the Wolbachia bacteria.

21 Oct 2011

Geron announces data from ongoing GRNOPC1 Phase 1 trial on spinal cord injury

Geron Corporation today announced two presentations on the company's ongoing Phase 1 clinical trial of its human embryonic stem cell-based therapy, GRNOPC1, in patients with spinal cord injury.

21 Oct 2011

Health prevention strategies can help Canadians achieve optimal health

Health prevention strategies to help Canadians achieve their optimal health potential could add a decade or more of healthy years to the average lifespan and save the economy billions of dollars as a result of reduced cardiovascular disease, says noted cardiologist Dr. Clyde Yancy.

21 Oct 2011

Genentech announces 96-week results from ocrelizumab Phase II study on RRMS

Genentech, a member of the Roche Group, today announced 96-week results from a Phase II study of ocrelizumab in patients with relapsing-remitting multiple sclerosis (RRMS), the most common clinical form of the disease.

21 Oct 2011

UH scientists recommend new drug strategies for chronic diseases

Researchers at the University of Houston (UH) are recommending a new strategy for developing drugs to treat cancer, multiple sclerosis, Alzheimer's and cardiovascular diseases.

21 Oct 2011

New 'law of biology' can predict patient-specific health events

Bioengineers from Rice University and physicians from Emory University are going to test whether a new "law of biology" can predict when a critically ill patient is about to worsen, and more importantly, which treatment is likely to prevent it.

21 Oct 2011

CERT gene silencing makes breast cancer cells more sensitive to drugs

CANCER RESEARCH UK scientists have discovered that switching off a gene called CERT makes breast cancer cells more sensitive to a range of drugs. The research is published in the Journal of Pathology.

21 Oct 2011

Dual role for VEGF in regulating skin cancer stem cells and tumor progression

In a study published in Nature, researchers lead by Cédric Blanpain, MD/PhD, FNRS/FRS researcher and WELBIO investigator at the IRIBHM, Université libre de Bruxelles, Belgium, in collaboration with the groups of Peter Carmeliet (VIB/K.U.Leuven) and Jody J. Haigh (VIB/UGent) identify a new role for Vascular Endothelial Growth Factor (VEGF) in regulating skin cancer stem cells.

21 Oct 2011

OncoGenex commences enrollment in OGX-427 Phase II trial for bladder cancer

OncoGenex Pharmaceuticals, Inc. announced today that it has initiated patient enrollment in a randomized, Phase II clinical trial evaluating OGX-427, an inhibitor of heat shock protein 27 (Hsp27), in patients with advanced bladder cancer.

21 Oct 2011

Mobile phones and brain cancer: the link may not be strong says new study

The largest study till date has refuted earlier fears that link mobile phone use to brain cancer. However experts say the risk can't be ruled out.

20 Oct 2011

Australian researchers make a quantum leap in understanding key cell structures

Researchers in Australia and the UK have made a world first discovery that will provide the most accurate understanding to date of the structure and function of the most important energy converting protein, critical to the function of all organs and a cause of disease when malfunctioning.

20 Oct 2011

Embryonic stem cell therapy patents knocked back in Europe

The European Union's highest court ruled Tuesday that scientists cannot patent stem cell techniques that use human embryos for research, a decision some scientists said could threaten major medical advances if it prevents biotech companies from turning a profit.

20 Oct 2011

Women with MET genetic variant and autoantibodies more likely to have autistic children

A study by researchers at UC Davis has found that pregnant women with a particular gene variation are more likely to produce autoantibodies to the brains of their developing fetuses and that the children of these mothers are at greater risk of later being diagnosed with autism.

20 Oct 2011