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NeuroVive, Selcia sign research collaboration agreement to develop new mitochondrial drugs

UK-based contract research organisation Selcia Limited and Swedish drug development company NeuroVive Pharmaceutical AB have signed a significant research collaboration agreement to develop new medicines and drug compounds targeting mitochondrial physiology and pathophysiology.

19 Sep 2011

NTNU genetic research shows best recipe to limit risk of lifestyle-related diseases

What should we eat? Answers abound in the international media, all of which rely on their interpretation of recent medical literature to come up with recommendations for the healthiest diet. But what if you could answer this question at a molecular level - what if you could find out how our genes respond to the foods we eat, and what this does to the cellular processes that make us healthy - or not? That's precisely what biologists at the Norwegian University of Science and Technology have done.

19 Sep 2011

University of Groningen surgeons perform first fluorescence-guided ovarian cancer surgery

The first fluorescence-guided surgery on an ovarian cancer patient was performed using a cancer cell "homing device" and imaging agent created by a Purdue University researcher.

19 Sep 2011

Two newer Type 2 diabetes drugs could be linked to increased risk of pancreatic cancer

Two newer drugs used to treat Type 2 diabetes could be linked to a significantly increased risk of developing pancreatitis and pancreatic cancer, and one could also be linked to an increased risk of thyroid cancer, according to a new UCLA study.

19 Sep 2011

Nanoparticles have a detrimental effect on the fish brain

Scientists at the University of Plymouth have shown, for the first time in an animal, that nanoparticles have a detrimental effect on the brain and other parts of the central nervous system.

19 Sep 2011

Researchers reveal crystal structure of dynamin protein

The crystal structure of the dynamin protein - one of the molecular machines that makes cells work - has been revealed, bringing insights into a class of molecules with a wide influence on health and disease.

19 Sep 2011

Landmark international study confirms common genetic contribution to mental illness

An international research consortium has confirmed that common genetic variants contribute to a person’s risk of schizophrenia and bipolar disorder. The largest study of its kind provides new molecular evidence that 11 regions have strong association with these diseases, including six regions not previously observed. The researchers also found that many of these DNA variations contribute to both diseases. The findings, reported by the Psychiatric Genome-Wide Association Study Consortium (PGC) and published online in two papers in the journal Nature Genetics, represent significant advances in the understanding the causes of these severe and often debilitating disorders.

18 Sep 2011

An evening of grace and glamour to benefit people living with HIV/AIDS in Orange County

AIDS Services Foundation Orange County (ASF) will literally roll out the red carpet for its signature fund raising event – Red Ball II on Saturday, September 24 at the Festival of Arts in Laguna Beach at 6 p.m.

17 Sep 2011

New insight into how nervous system regulates immunity

Scientists have identified a surprising new role for a new type of T cell in the immune system: some of them can be activated by nerves to make a neurotransmitter (acetylcholine) that blocks inflammation. The discovery of these T cells is novel and suggests that it may be possible to treat inflammation and autoimmune diseases by targeting the nerves and the T cells. The study was published this week in Science.

17 Sep 2011

Researchers show how protein fortilin promotes growth of cancer cells

Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of Texas Medical Branch may lead to treatments for a range of cancers and atherosclerosis, which p53 also helps prevent, and appears in the current print issue of the Journal of Biological Chemistry.

17 Sep 2011

DARA's KRN5500 meets primary end-points in Phase II study for chemotherapy-induced neuropathic pain

Thanks to greater awareness, earlier detection and improving therapeutic agents, people with cancer are living longer than ever before. One of the consequences of living longer is the symptom burden of cancer survivorship, which may have a substantial impact on quality of life for many survivors. One such burden is the pain syndromes resulting from cancer treatments.

17 Sep 2011

BARDA awards Vaxin $21.7M contract to accelerate development of novel anthrax vaccine

Vaxin Inc., a clinical stage vaccine development company, today announced that it has been awarded a contract valued at up to $21.7 million by the Office of Biomedical Advanced Research and Development Authority (BARDA) for pre-clinical assessment, final manufacturing process development and the supply of clinical materials to support an IND filing and first-in-man dose ranging study of the company's proprietary anthrax vaccine, AdVAV.

17 Sep 2011

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

17 Sep 2011

Adult stem cells hold hope for treatment of lupus

With a patient's own adult stem cells, there is new hope for the intractable autoimmune disease lupus - systemic lupus erythematosus (SLE) - which is difficult to cure.

17 Sep 2011

Nanion’s automated patch clamp platforms show unparalleled results using stem cell derived cardiomyocytes

The Patchliner and the SyncroPatch 96 have successfully been used for compound analysis under current- and voltage clamp recording conditions using different stem cell-derived cardiomyocytes. The exceptional cell-platform-compatibility and the unique experimental possibilities offered by Nanion’s platforms open up whole new avenues for compound safety testing.

16 Sep 2011

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced results from an investigational Phase 3b clinical study in which the addition of ONGLYZA (saxagliptin) 5 mg to ongoing insulin therapy (with or without metformin) maintained reductions of blood sugar levels (glycosylated hemoglobin levels, or HbA1c) in adult patients with type 2 diabetes compared to the addition of placebo (with or without metformin) from 24 to 52 weeks.

16 Sep 2011

Life Technologies praises Obama's signing of the America Invents Act

Life Technologies Corporation applauds the signing by President Barack Obama of "The Leahy-Smith America Invents Act" (H.R. 1249). President Obama will sign the bill today at Thomas Jefferson High School for Science and Technology in Alexandria, Virginia.

16 Sep 2011

Cell News and Research

NeuroVive, Selcia sign research collaboration agreement to develop new mitochondrial drugs

NTNU genetic research shows best recipe to limit risk of lifestyle-related diseases

University of Groningen surgeons perform first fluorescence-guided ovarian cancer surgery

Two newer Type 2 diabetes drugs could be linked to increased risk of pancreatic cancer

Nanoparticles have a detrimental effect on the fish brain

Researchers reveal crystal structure of dynamin protein

Landmark international study confirms common genetic contribution to mental illness

An evening of grace and glamour to benefit people living with HIV/AIDS in Orange County

New insight into how nervous system regulates immunity

Researchers show how protein fortilin promotes growth of cancer cells

DARA's KRN5500 meets primary end-points in Phase II study for chemotherapy-induced neuropathic pain

BARDA awards Vaxin $21.7M contract to accelerate development of novel anthrax vaccine

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

Adult stem cells hold hope for treatment of lupus

Nanion’s automated patch clamp platforms show unparalleled results using stem cell derived cardiomyocytes

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Life Technologies praises Obama's signing of the America Invents Act

Anavex announces ANAVEX pre-clinical data on Alzheimer's disease

Novel imaging technique reveals new visual resolution of NK cell action

Scientists investigate how rhythmic activity of nerve cells supports spatial navigation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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