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Ethnic differences in genetic factors may affect susceptibility to development of breast cancer

A new study finds that factors known to increase the risk of breast cancer among white women have less influence in Hispanic women. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that research is needed to evaluate how breast cancer risk factors differ among ethnic and racial populations.

26 Apr 2010

Controlling actions of FSH may help treat osteoporosis in menopausal women

Diminished bone density is common among menopausal women and raises their risk of osteoporosis, bone fractures and subsequent complications. Research has traditionally focused on therapies that seek to maintain the level of estrogen in the body. This hormone seems to sustain bone health, but it drops to an extremely low level during and after menopause.

26 Apr 2010

Study finds changes in astrocytes key to brain dysfunction

Neuroscience researchers have zeroed in on a novel mechanism that helps control the firing of electrical signals among neurons. By isolating the molecular and electrical events that occur when this control is disrupted, the new research sheds light on epileptic seizures and potentially on other prominent diseases involving poorly regulated brain activity.

26 Apr 2010

Targeted therapy based on molecular signatures for treating lung cancer

The first lung cancer clinical trial to guide targeted therapies to patients based on molecular signatures in tumor biopsies is a step toward personalized care and more effective, efficient clinical trials for new drugs, study leaders reported today during the American Association for Cancer Research 101st Annual Meeting 2010.

24 Apr 2010

1976 "swine flu" vaccine protects against 2009 pandemic H1N1 influenza virus

New evidence shows immunization against "swine flu" in 1976 might provide individuals with some protection against the 2009 pandemic H1N1 influenza virus, according to new research from St. Jude investigators.

24 Apr 2010

New understanding of nerve cell influence in exchange of information

Nerve cells communicate with each other by means of electrical impulses. To create such an impulse, the cells exchange charged ions with their environment. However, the role played by the ever-present chloride channels remained obscure, although some theories predicted a relation between the chloride channel ClC-2 and epilepsy.

24 Apr 2010

JHUSON introduces Text4Baby program to provide parenting tips to new parents

Having a baby is a very exciting time for new parents, with all the preparation and anticipation that comes with it. But how do parents find help and assistance—from prenatal care to parenting tips? Researchers at the Johns Hopkins University School of Nursing have come up with innovative ways to provide parenting tips to new parents of all demographics.

24 Apr 2010

Mechanisms pathogenic viruses exploit to evade immune systems of hosts

Viruses have evolved a broad range of strategies that enable them to evade the immune systems of their hosts. A team of researchers led by LMU virologist Professor J-rgen Haas has been studying a novel, recently discovered mechanism that pathogenic viruses exploit for this purpose, and their latest results could point the way to new antiviral therapies. The mechanism is based on the production of short RNA molecules, called microRNAs, by the virus.

24 Apr 2010

Novel clinical research approaches for rapidly identifying and preventing congenital cardiovascular defects

Structural and functional congenital cardiovascular abnormalities present at birth are the leading source of all congenital defects encountered in live births. Nearly half a million children in the United States have structural heart problems ranging in severity from relatively simple issues, such as small holes between chambers of the heart, to very severe malformations, including complete absence of one or more chambers or valves.

24 Apr 2010

Myths and facts about pediatric cancer

"Your child has cancer." They are words every parent can't imagine hearing.

24 Apr 2010

Programs to address care for children born with SCD during adulthood

Forty years ago, children born with sickle cell disease (SCD) were not expected to live past their teenage years. Today, medical advances are allowing children to live well into adulthood, raising concerns over who is going to care for these patients as adults. However, programs are underway to address these concerns, as reported in the March/April edition of Journal of Pediatric Oncology Nursing, published by the Association of Pediatric Hematology/Oncology Nurses (APHON).

24 Apr 2010

Current concepts and recent research findings on gene therapy for inner ear disorders

Gene therapy holds great potential for the treatment not only of genetic disorders, but also of many acquired diseases. This is as true for the inner ear as for any other organ. However, the technical challenges that must be overcome before gene therapy becomes more widely used are remarkable. In the inner ear the size, accessibility, delicacy and the involvement of many different cell types present unique conditions.

24 Apr 2010

Animal studies demonstrate safety profile of ACT's RPE cell therapy for SMD

Advanced Cell Technology, Inc. announced today that it has completed key animal studies in connection with its Phase I multicenter study using embryonic stem cell derived Retinal Pigment Epithelium (RPE) cells to treat patients with Stargardt's Macular Dystrophy (SMD), for which it filed an Investigational New Drug Application (IND) with the US Food and Drug Administration (FDA) in November. The studies demonstrated an excellent safety profile with no safety signals such as tumors or ectopic tissues.

24 Apr 2010

AlloMap molecular expression test reduces need for invasive heart-muscle biopsies

Monitoring rejection in heart transplantation patients with a simple blood test co-developed by NewYork-Presbyterian Hospital/Columbia University Medical Center physician-scientist Dr. Mario Deng in 2005 can safely reduce their need for invasive heart-muscle biopsies, a new study has found.

24 Apr 2010

New hopes to improve cancer diagnosis and treatment for children

Motivated clinicians and an Internet connection combined with computers and e-mail access have the power to transform pediatric cancer treatment in the most remote corners of earth, according to a St. Jude investigator writing in a recent issue of The Lancet Oncology.

24 Apr 2010

Continuous flow mechanical circulatory support devices improve outcomes in patients awaiting heart transplants

New data show improved outcomes, better survival rates and lower costs with the use of continuous flow mechanical circulatory support devices in patients awaiting heart transplants. Research will be presented this week during symposia at the International Society for Heart and Lung Transplantation (ISHLT) 30th Annual Meeting and Scientific Session at the Hilton Chicago.

24 Apr 2010

SuperSonic Imagine reports results of largest worldwide multicenter clinical breast study in ultrasound imaging

SuperSonic Imagine, the innovative medical imaging company based in Aix-en-Provence, France has unveiled some of the results of the largest clinical breast study ever undertaken in ultrasound imaging. The worldwide multicenter study, involving top clinicians in the breast radiology community, is assessing the clinical benefits of ShearWave™ Elastography in the ultrasonic evaluation of breast lesions.

24 Apr 2010

McGill researchers receive $1.7M for 10 cutting-edge research projects

Ten McGill University researchers received an important boost today, by way of the announcement of $1.7 million in new funding awarded through the Canada Foundation for Innovation's Leaders Opportunity Fund. "CFI investments are critical for our research leaders, to ensure that their research remains innovative and second to none," said Dr. Rima Rozen, Interim Vice-Principal (Research and International Relations) at McGill.

24 Apr 2010

Moffitt Cancer Center reports increasing interest in ERCC1 Analysis test for selecting chemotherapy for NSCLC

Moffitt Cancer Center announces steadily growing interest in the ERCC1 Analysis, the first test developed for selecting chemotherapy for Non Small Lung Cancer patients. Each year, more than 200,000 Americans are diagnosed with lung cancer.

24 Apr 2010

Cardiola's m.pulse MCP based system improves cardiac function in stable CHF patients

Cardiola AG announced today that the Company's CE-Marked m.pulse® Muscular CounterPulsation ("MCP")-based system demonstrated "an immediate improvement of cardiac output with non-invasive means" in a patient population of advanced yet stable chronic heart failure. The effects could be shown in 22 patients over three consecutive days.

24 Apr 2010

Cell News and Research

Ethnic differences in genetic factors may affect susceptibility to development of breast cancer

Controlling actions of FSH may help treat osteoporosis in menopausal women

Study finds changes in astrocytes key to brain dysfunction

Targeted therapy based on molecular signatures for treating lung cancer

1976 "swine flu" vaccine protects against 2009 pandemic H1N1 influenza virus

New understanding of nerve cell influence in exchange of information

JHUSON introduces Text4Baby program to provide parenting tips to new parents

Mechanisms pathogenic viruses exploit to evade immune systems of hosts

Novel clinical research approaches for rapidly identifying and preventing congenital cardiovascular defects

Myths and facts about pediatric cancer

Programs to address care for children born with SCD during adulthood

Current concepts and recent research findings on gene therapy for inner ear disorders

Animal studies demonstrate safety profile of ACT's RPE cell therapy for SMD

AlloMap molecular expression test reduces need for invasive heart-muscle biopsies

New hopes to improve cancer diagnosis and treatment for children

Continuous flow mechanical circulatory support devices improve outcomes in patients awaiting heart transplants

SuperSonic Imagine reports results of largest worldwide multicenter clinical breast study in ultrasound imaging

McGill researchers receive $1.7M for 10 cutting-edge research projects

Moffitt Cancer Center reports increasing interest in ERCC1 Analysis test for selecting chemotherapy for NSCLC

Cardiola's m.pulse MCP based system improves cardiac function in stable CHF patients

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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