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Academic Health Center receives 128 grants totaling nearly $35 million in federal stimulus money

Academic Health Center scientists, physicians, and research centers have attracted 128 grants totaling nearly $35 million in federal stimulus money (as of Nov. 10) since the American Recovery and Reinvestment Act was approved in February 2009. This will result in a total economic impact of more than $105 million; according to the National Institutes of Health, $1 of research funding multiplies to more than $2 of goods and services in the economy.

11 Nov 2009

NIDA supports new drug detection research

Every time a person snorts cocaine, it doesn't just go to his or her head: It also provokes a response in the immune system, creating special biomolecules that may serve as a permanent record of each exposure.

11 Nov 2009

Sprycel holds hope for treating Src dependent ovarian cancer

The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA's Jonsson Comprehensive Cancer Center found.

11 Nov 2009

Researchers identify cause that leads to age-related hearing loss

Age-related hearing loss is the most common sensory disorder among the elderly. But scientists are still trying to figure out what cellular processes govern or contribute to the loss.

11 Nov 2009

HFSP grant to develop molecular probes to study "cellular GPS" system

An international group of researchers from Carnegie Mellon University, Goettingen Medical School in Germany and the University of Cambridge in the United Kingdom have received a Human Frontiers Science Program (HFSP) grant to develop molecular probes that will help researchers better understand the "cellular GPS" system that guides neurons to create a properly wired nervous system.

11 Nov 2009

Anemia-reducing medications linked to deep vein thrombosis in cancer patients

Medications frequently given to cancer patients to reduce their risk of anemia are associated with an increased risk of deep vein thrombosis or pulmonary embolism, according to new research led by Dawn Hershman, M.D, M.S., co-director of the breast cancer program at the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital/Columbia University Medical Center. The findings will be published online on Nov. 10, 2009 in the Journal of the National Cancer Institute (ahead of the Dec. 2, 2009 print edition).

11 Nov 2009

Potential new drug for lung cancer eliminates tumors in mice

A potential new drug for lung cancer has eliminated tumours in 50% of mice in a new study published today in the journal Cancer Research. In the animals, the drug also stopped lung cancer tumours from growing and becoming resistant to treatment. The authors of the research, from Imperial College London, are now planning to take the drug into clinical trials, to establish whether it could offer hope to patients with an inoperable form of lung cancer.

11 Nov 2009

Texting linked to pain in neck and shoulders among college students

The world record for fastest text message typing is held by a 21-year old college student from Utah, but his dexterous digits could mean serious injury later on. Most adults aged 18-21 prefer texting over e-mail or phone calls, and ergonomics researchers are starting to wonder whether it's putting the younger generation at risk for some overuse injuries - once reserved for older adults who have spent years in front of a computer.

10 Nov 2009

NIH $1 million Challenge Grant to refine cell-tracking nanotube technology

The National Institutes of Health (NIH) has awarded researchers at Rice University and the Texas Heart® Institute (THI) a $1 million Challenge Grant to refine cell-tracking nanotube technology that could make magnetic resonance imaging (MRI) up to 40 times more sensitive than existing MRIs and help guide adult stem cells within the human body to repair damaged hearts.

10 Nov 2009

BioVex completes $70M financing to complete OncoVEX Phase III study

BioVex Inc, a company developing new generation biologics for the treatment and prevention of cancer and infectious disease, announced today that it has concluded a $70 million private financing, raising $30 million in addition to the $40 million announced in March. The proceeds of the financing will primarily be used to complete the ongoing Phase III pivotal study of OncoVEX (GM-CSF) for the treatment of recurrent and metastatic melanoma and to fund pre-commercialization activities.

10 Nov 2009

ImmunoGen to present IMGN901 clinical data at AACR-NCI-EORTC International Conference

ImmunoGen, Inc., a biopharmaceutical company that develops targeted anticancer therapeutics, announced today that several ImmunoGen poster presentations will be made at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics to be held in Boston, MA, on November 15-19, 2009.

10 Nov 2009

Levulan PDT may reduce the rate of recurrence of SCCs in solid organ transplant recipients: Study

The results of an independent investigator study just published in the online version of Dermatologic Surgery demonstrate that Levulan(®) Photodynamic Therapy (PDT) may reduce the rate of recurrence of squamous cell carcinomas (SCCs) in solid organ transplant recipients (SOTRs), a population with a high incidence of nonmelanoma skin cancer.

10 Nov 2009

Mesenchymal stem cells may be the key to healing diabetic foot ulcers

Diabetic foot ulcers are the primary cause of hospital admissions for diabetics. Foot ulcers that heal improperly are at risk for infection, which can lead to amputation. According to the American Diabetes Association, one in four patients with diabetic foot ulcers will eventually require lower-limb amputation. Now science has found a way of mobilizing stem cells within the body to treat this health issue, which affects more than three million Americans annually.

10 Nov 2009

Trinity Health to install Elsevier's online CDS solutions

Elsevier (http://www.elsevier.com), a world leader in healthcare and medical publishing and online solutions, today announced that Trinity Health (http://www.trinity-health.org), the nation's fourth largest Catholic health system with 44 hospitals across eight states, will install seven of Elsevier's online clinical decision support (CDS) solutions to meet the evolving needs of its thousands of physicians, nurses, pharmacists and allied health professionals for evidence-based clinical content.

10 Nov 2009

OriGene Technologies' over-expression lysates adopted for Human Protein Atlas project

OriGene Technologies, Inc. today announced Royal Institute of Technology in Sweden has adopted its VERIFY Tagged Antigen(TM) (Over-expression Lysates) in the Human Protein Atlas program. This program is funded by the Knut and Alice Wallenberg Foundation and is set up to explore the human proteome systematically using Antibody-Based Proteomics.

10 Nov 2009

Researchers discover cells that protect the respiratory tract from developing an allergic response

According to the great paradigms of immunology, asthma, an allergic disease of the respiratory system, should always develop upon exposure to airborne antigens that are constantly being inhaled. However, the fact that 94 % of the Western population does not develop the disease suggests that as yet undefined mechanisms protect the respiratory tract from developing an allergic response. A team of researchers at University of Liege (Belgium), GIGA Research Center, led by Professor Fabrice Bureau, has shown that asthma is inhibited by regulatory macrophages, a cell population never previously described.

10 Nov 2009

Study suggests a new improved treatment option for children with Hurler's syndrome

Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme - preventing or reducing organ and central nervous system damage from the often-fatal genetic disorder Hurler's syndrome.

10 Nov 2009

Study on how robust antibodies work to block the HIV virus raise hope for new vaccine

A very close and detailed study of how the most robust antibodies work to block the HIV virus as it seeks entry into healthy cells has revealed a new direction for researchers hoping to design an effective vaccine.

10 Nov 2009

Activating TAp63 protein, a viable anti-cancer strategy

Oncologists have had their hands tied because more than half of all human cancers have mutations that disable a protein called p53. As a critical anti-cancer watchdog, p53 masterminds several cancer-fighting operations within cells. When cells lose p53, tumors grow aggressively and often cannot be treated.

10 Nov 2009

Scientists find way to splice cell networks down to their genesis

On Noah's Ark animals came in twos: male and female. In human bodies trillions of cells are coupled, too, and so are the molecules from which they are composed. Yet these don't come in twos, they are regrouped into indistinguishable clusters. Because these complex cell networks are the backbone of life - and illness - scientists have long searched for ways to splice cell clusters down to their original pairs.

10 Nov 2009

Cell News and Research

Academic Health Center receives 128 grants totaling nearly $35 million in federal stimulus money

NIDA supports new drug detection research

Sprycel holds hope for treating Src dependent ovarian cancer

Researchers identify cause that leads to age-related hearing loss

HFSP grant to develop molecular probes to study "cellular GPS" system

Anemia-reducing medications linked to deep vein thrombosis in cancer patients

Potential new drug for lung cancer eliminates tumors in mice

Texting linked to pain in neck and shoulders among college students

NIH $1 million Challenge Grant to refine cell-tracking nanotube technology

BioVex completes $70M financing to complete OncoVEX Phase III study

ImmunoGen to present IMGN901 clinical data at AACR-NCI-EORTC International Conference

Levulan PDT may reduce the rate of recurrence of SCCs in solid organ transplant recipients: Study

Mesenchymal stem cells may be the key to healing diabetic foot ulcers

Trinity Health to install Elsevier's online CDS solutions

OriGene Technologies' over-expression lysates adopted for Human Protein Atlas project

Researchers discover cells that protect the respiratory tract from developing an allergic response

Study suggests a new improved treatment option for children with Hurler's syndrome

Study on how robust antibodies work to block the HIV virus raise hope for new vaccine

Activating TAp63 protein, a viable anti-cancer strategy

Scientists find way to splice cell networks down to their genesis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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