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Preclinical data of carfilzomib and PR-957 inhibitors to be presented at 2009 ACR/ARHP meeting

Proteolix, Inc. today announced that data from preclinical studies of carfilzomib and PR-957 will be presented at the 2009 ACR/ARHP Annual Scientific Meeting on October 16 - 21 in Philadelphia, PA.

19 Oct 2009

Discovery may yield better understanding of protective gut-dwelling bacteria

Medical researchers have long suspected that obscure bacteria living within the intestinal tract may help keep the human immune system in balance. An international collaboration co-led by scientists at NYU Langone Medical Center has now identified a bizarre-looking microbial species that can single-handedly spur the production of specialized immune cells in mice.

19 Oct 2009

NCCN Clinical Practice Guidelines in Oncology updated to include pralatrexate drug

NCCN has added pralatrexate (Folotyn(TM), Allos Therapeutics, Inc.) to the NCCN Guidelines for Non-Hodgkin's Lymphomas as one of the options for second-line therapy for relapsed or refractory peripheral T-cell lymphoma.

19 Oct 2009

Chrysanthemum indicum extract holds promise for treating human cancer

A series of studies have demonstrated that Chrysanthemum indicum possesses antimicrobial, antiinflammatory, immunomodulatory, and neuroprotective effects. Recently, much attention has been devoted to the anticancer activity of Chrysanthemum indicum, especially in hepatocellular carcinoma (HCC). However, its anticancer mechanism of action is still not clear and needs further investigation.

19 Oct 2009

Stem cell treatments could repair the kidney defects associated with Alport syndrome

Several cell-based therapy approaches could provide new treatments for patients with Alport syndrome, reports an upcoming paper in the Journal of the American Society of Nephrology (JASN). "Our study opens up many considerations of how new therapies related to the use of stem cells can be devised for our kidney patients with chronic disease," comments Raghu Kalluri, MD, PhD (Harvard Medical School, Boston, MA).

19 Oct 2009

Immune-related proteins are potential drug targets for gastric inflammation and cancer

A research team from South Korea studied the complex reaction of gastric inflammation induced by Helicobacter pylori (H pylori) in a systematic manner using a protein interaction network. Their study will be published on September 28, 2009 in the World Journal of Gastroenterology.

19 Oct 2009

Researchers find the genetic mutation that is linked with changes in brain development

For decades, scientists have thought the faulty neural wiring that predisposes individuals to behavioral disorders like autism and psychiatric diseases like schizophrenia must occur during development. Even so, no one has ever shown that a risk gene for the disease actually disrupts brain development.

19 Oct 2009

New scientific journal from Elsevier

Elsevier, a world-leading publisher of scientific, technical and medical information products and services announced today the launch of a new peer-reviewed scientific journal, Spatial and Spatio-temporal Epidemiology (http://www.elsevier.com/locate/sste).

19 Oct 2009

Research study on cowpox virus

In the annals of medicine, Edward Jenner's 1796 vaccination of a young boy against smallpox, using fluid from cowpox blisters, remains a landmark case. In a new study, Kathryn Sykes, a researcher at Arizona State University's Biodesign Institute and her colleagues have taken a fresh look at cowpox.

19 Oct 2009

Rituxan's sBLA receives a Complete Response from the FDA

Genentech, Inc. a wholly-owned member of the Roche Group, and Biogen Idec announced today that the companies received a Complete Response from the U.S. Food and Drug Administration (FDA) for a supplemental Biologics License Application (sBLA) for Rituxan (rituximab) plus methotrexate (MTX) in patients with moderately-to-severely active rheumatoid arthritis (RA) who no longer respond to treatment with a disease modifying antirheumatic drug (DMARD), including MTX.

19 Oct 2009

Ethics in biomedical research: One-year grant from NIH to develop interactive educational software

Arkitek Studios and the Northwest Association for Biomedical Research (NWABR) have been awarded a $100,000 Phase I Small Business Innovation Research (SBIR) grant from the National Center for Research Resources, a component of the National Institutes of Health. This one-year grant, entitled ETHOS (Ethics Training Health Oriented Software), provides funding for development of interactive educational software that will underscore the critical role ethics plays in biomedical research.

19 Oct 2009

New chromosomal abnormality in acute lymphoblastic leukemia

Researchers identified a new chromosomal abnormality in acute lymphoblastic leukemia (ALL) that appears to work in concert with another mutation to give rise to cancer. This latest anomaly is particularly common in children with Down syndrome.

19 Oct 2009

DKC establishes link between genetic mutation affecting telomerase function and human disease

The human genetic disease dyskeratosis congenita (DKC) is an autosomal dominant disease that leads to abnormalities in tissues with a rapid cell turnover - the skin, nails, bone marrow, lungs and gut. Patients with DKC experience life-threatening symptoms. Bone marrow failure increases their risk of fatal infections and cancer. Many die before the age of 30 and management of the disease is limited to trying to treat its symptoms.

19 Oct 2009

Cardium Therapeutics reports positive findings from Excellarate Phase 1/2 clinical study

Cardium Therapeutics today announced the publication of positive findings from the open label multi-center Phase 1/2 clinical study of Excellarate(TM) (GAM501, Ad5PDGF-B / 2.6% collagen), its product candidate for the potential treatment of non-healing diabetic foot ulcers.

19 Oct 2009

DFG Research Centre to be funded for a further four-year period

The DFG Research Centre for Renewable Therapies at the Technical University of Dresden ("Renewable Therapies: From Cells to Tissues to Therapies - Engineering the Cellular Basis of Regeneration ", CRTD), following a very successful first funding period, is being extended and will be funded for a further four years.

19 Oct 2009

Novel HIV drug to be studied in cell cultures and patients

A $6 million, five-year federal grant to The Children's Hospital of Philadelphia Research Institute will enable researchers to investigate a novel approach in treating HIV infection---a unique class of drugs focused on developing therapies for psychological and neurological effects in AIDS.

19 Oct 2009

NCCN program on Discovery Health Channel profiles patients battling lung cancer

Lung cancer is the second most common cancer and leading cause of cancer-related deaths in both men and women. Although tobacco use is the strongest known risk factor for lung cancer, many people who never smoked also develop the disease.

19 Oct 2009

Clemson University receives a $9.3M NIH grant to establish a tissue regeneration center

Clemson University has received a $9.3 million, five-year National Institutes of Health (NIH) grant to establish a Center of Biomedical Research Excellence (COBRE) for Tissue Regeneration. Faculty from the Medical University of South Carolina and the University of South Carolina also will collaborate, providing expertise in medicine and developmental biology.

19 Oct 2009

Institute Curie Hospital in France adds another TomoTherapy radiation therapy system

TomoTherapy Incorporated announced today that the Institute Curie Hospital in France has purchased a second TomoTherapy® radiation therapy system, to support the increasing demand for intensity-modulated radiation therapy (IMRT). The Institute Curie Hospital has been treating cancer patients with TomoTherapy technology since March 2007, when it became the first hospital in France to adopt the technology.

19 Oct 2009

Mothers receiving HAART less likely to transmit HIV virus to their newborns through breastfeeding

Mothers receiving highly active antiretroviral therapy (HAART) to treat HIV-1 infection are less likely than untreated mothers to transmit the virus to their newborns through breastfeeding, according to a new study.

19 Oct 2009

Cell News and Research

Preclinical data of carfilzomib and PR-957 inhibitors to be presented at 2009 ACR/ARHP meeting

Discovery may yield better understanding of protective gut-dwelling bacteria

NCCN Clinical Practice Guidelines in Oncology updated to include pralatrexate drug

Chrysanthemum indicum extract holds promise for treating human cancer

Stem cell treatments could repair the kidney defects associated with Alport syndrome

Immune-related proteins are potential drug targets for gastric inflammation and cancer

Researchers find the genetic mutation that is linked with changes in brain development

New scientific journal from Elsevier

Research study on cowpox virus

Rituxan's sBLA receives a Complete Response from the FDA

Ethics in biomedical research: One-year grant from NIH to develop interactive educational software

New chromosomal abnormality in acute lymphoblastic leukemia

DKC establishes link between genetic mutation affecting telomerase function and human disease

Cardium Therapeutics reports positive findings from Excellarate Phase 1/2 clinical study

DFG Research Centre to be funded for a further four-year period

Novel HIV drug to be studied in cell cultures and patients

NCCN program on Discovery Health Channel profiles patients battling lung cancer

Clemson University receives a $9.3M NIH grant to establish a tissue regeneration center

Institute Curie Hospital in France adds another TomoTherapy radiation therapy system

Mothers receiving HAART less likely to transmit HIV virus to their newborns through breastfeeding

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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