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Stem cell breakthrough offers diabetes hope

Scientists have discovered a new technique for turning embryonic stem cells into insulin-producing pancreatic tissue in what could prove a significant breakthrough in the quest to find new treatments for diabetes.

From The University of Manchester 4 Apr 2008

Discovery of new genetic links to psoriasis

In the first comprehensive study of the genetic basis of psoriasis, researchers at Washington University School of Medicine in St. Louis have discovered seven new sites of common DNA variation that increase the risk of the troublesome skin condition.

4 Apr 2008

Researchers learn how signaling molecule orchestrates breast cancer's spread

A study led by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) has uncovered how breast tumors use a particular type of molecule to promote metastasis -- the spread of cancer cells. Metastasis is the cause of approximately 90 percent of all cancer-related deaths.

4 Apr 2008

Rare genetic syndrome may hold key to cure for heat stroke

A genetic disorder that can cause a fatal rise in body temperature in some patients undergoing general anesthesia may hold the key to a cure for heat stroke, according to research published in the April 4 edition of the journal Cell.

4 Apr 2008

Mitosis gets harder thanks to new gene discovery

A biological process taught to every pupil studying science at high school has just become a little more complicated thanks to a new discovery published today.

4 Apr 2008

Human breast tumors' 'microenvironment' primes them for metastasis

The environment within primary breast tumors can "empower" cells that break free and enter the bloodstream to successfully invade other organs, researchers report in the April 4th Cell, a publication of Cell Press.

4 Apr 2008

Enzyme complex could be key to new cancer treatments

Penn State scientists are the first to observe in living cells a key step in the creation of adenine and guanine, two of the four building blocks that comprise DNA.

4 Apr 2008

Clinical trial to test a novel HIV/AIDS vaccine

This new vaccine aims to overcome the problem of preexisting immunity to common vaccine vectors, which is thought to be a major problem in the developing world.

4 Apr 2008

Alcohol alters prefrontal cortex activity through ion channel disruption

The prefrontal cortex (PFC) region of the brain is involved in decision making. New rodent findings show that PFC neuron N-methyl-D-aspartic acid (NMDA) receptors are especially sensitive to concentrations of alcohol achieved during drinking.

4 Apr 2008

Proteolix's Carfilzomib granted orphan drug designation

Proteolix, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to carfilzomib, a selective blocker of proteasome activity for the treatment of multiple myeloma.

3 Apr 2008

New nano-engineered gel inhibits for spinal cord injury

A spinal cord injury often leads to permanent paralysis and loss of sensation below the site of the injury because the damaged nerve fibers can't regenerate.

3 Apr 2008

Discovery of gene variant linked to nicotine addiction and lung cancer

Scientists have identified a genetic variant that not only makes smokers more susceptible to nicotine addiction but also increases their risk of developing two smoking-related diseases, lung cancer and peripheral arterial disease.

3 Apr 2008

Genetic variations raise lung cancer risk for smokers and ex-smokers

Two common inherited genetic variations are associated with increased risk of lung cancer for smokers and former smokers, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports April 2 in the online edition of Nature Genetics.

3 Apr 2008

Genetic mutations tied to immune comeback during therapy for HIV-1

Researchers with the Infectious Disease Clinical Research Program (IDCRP) at the Uniformed Services University of the Health Sciences (USU) here and the University of Texas Health Science Center at San Antonio have published a patient outcome study in the March 30 online edition of Nature Medicine that may signal a need for a change of thought in the management of HIV.

3 Apr 2008