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New technology tracks medication adherence in patients with HIV/AIDS

Most of us have missed a dose of antibiotic or forgotten to take a daily vitamin. But when the stakes are higher - as they are for people with HIV/AIDS - a skipped pill could mean the difference between health and hazard for the entire population.

21 Apr 2008

Discovery of fundamental mechanism of how tumour cells communicate

A new fundamental mechanism of how tumour cells communicate has just been discovered by the team of Dr. Janusz Rak at the Research Institute of the McGill University Health Centre (MUHC) in collaboration with Dr Guha from the University of Toronto.

21 Apr 2008

Mending tendons without surgery

James McGillicuddy was not getting good news. Three years after arriving at Stanford as one of the nation's top high school football recruits, he'd been stuck on the sidelines the entire time by a torn tendon that, even with two surgeries, just wouldn't stay fixed. More surgery would not help, his doctors told him, but they did have one last option to offer him.

21 Apr 2008

Raptor Pharmaceuticals initiates phase IIa clinical study for Convivia

Raptor Pharmaceuticals Corp. has announced that its clinical development subsidiary, Bennu Pharmaceuticals Inc. , has initiated the Company's first clinical-stage program after dosing the first cohort in a Phase IIa study of oral 4-methylpyrazole ("4-MP") in subjects with ALDH2 deficiency, or ethanol intolerance, as the initial development stage of its Convivia program.

21 Apr 2008

Genentech updates on phase III study of Avastin plus chemo in first-line, advanced, non-squamous, non-small cell lung cancer

Genentech, Inc. has announced an update for the previously reported Roche-sponsored international Phase III clinical study (AVAiL) of Avastin (bevacizumab) in combination with gemcitabine and cisplatin chemotherapy, in patients with advanced, non-squamous, non-small cell lung cancer (NSCLC).

21 Apr 2008

New method for testing treatments for Chagas' disease

Chagas' disease is a tropical parasitic sickness that currently affects more than 16 million people, with a staggering 100 million at risk, largely in the tropical areas of South and Central America. And yet the main drug used to treat the disease is highly toxic and causes serious side effects.

20 Apr 2008

Chronic inflammation triggers cell fusions that could protect neurons

Chronic inflammation triggers bone marrow-derived blood cells to travel to the brain and fuse with a certain type of neuron up to 100 times more frequently than previously believed, according to a new study from the Stanford University School of Medicine.

20 Apr 2008

A genetic variation mimics effect of heart failure medications - may explain why beta-blockers do not work for all patients

A genetic variation, found predominantly in African Americans, protects some people with heart failure, enabling them to live longer than expected. That's the conclusion of a research team led by investigators at the University of Maryland School of Medicine in Baltimore and the Washington University School of Medicine in St. Louis.

20 Apr 2008

Discovery of method for clamping down on a cancer-promoting enzyme

There are many pathways that allow an errant gene to turn a cell cancerous, and a number of these pathways go through a single enzyme called the p21-activated kinase 1, or PAK1.

18 Apr 2008

Vitamin D and the risk of developing breast cancer

A connection between vitamin D level and the risk of developing breast cancer has been implicated for a long time, but its clinical relevance had not yet been proven.

18 Apr 2008

Aida Pharmaceuticals announces development of new anti-cancer drug

Aida Pharmaceuticals, Inc. has announced that it is developing a potential cancer drug that seeks to trigger cell death in certain types of cancer.

18 Apr 2008

Fluorine-based nanoparticles on track to improve cancer detection and therapy

Perfluorocarbons, a class of inert, oily polymers, have a proven track record in a variety of clinical uses, including in contrast-enhanced ultrasound imaging and in eye surgery to correct a detached retina.

18 Apr 2008

Quantum rods light up pancreatic cancer cells

Quantum dots have shown promise as ultrabright contrast agents for use in a variety of cancer imaging studies. Now, a team of investigators at the Multifunctional Nanoparticles in Diagnosis and Therapy of Pancreatic Cancer Platform Partnership, headed by Paras Prasad, Ph.D., of the State University of New York at Buffalo, has shown that quantum rods may perform even better than their spherical cousins.

18 Apr 2008

Iron nanoparticles spot tumor spread in patients with kidney cancer

Iron nanoparticles designed to collect in lymph nodes containing metastatic cancer cells have proven that they can help physicians detect metastatic spread of prostate cancer.

18 Apr 2008

Mature B cells reprogrammed to stem-cell-like state

Fully mature, differentiated B cells can be reprogrammed to an embryonic-stem-cell-like state, without the use of an egg, according to a study published in the April 18 issue of Cell.

18 Apr 2008

Biomoda granted 'notice of allowance' for U.S. patent protection for additional IP

Biomoda, Inc., a development stage medical diagnostics company, announced it has been granted a notice of allowance from the U.S. Patent and Trademark Office for its invention directed to the "Method for Prognosing Response to Cancer Therapy with 5,10,15,20-Tetrakis (Carboxyphenyl) Porphine."

18 Apr 2008

Interaction networks: the new path to drug discovery

Although the pharmaceutical industry has dedicated enormous research efforts over the last 50 years to identify new targets and develop new active ingredients, these efforts have met with limited success.

17 Apr 2008

Breastfeeding during anti-epilepsy drug treatment does not appear to harm a child's cognitive development

A first of its kind study finds breastfeeding while taking certain seizure medications does not appear to harm a child's cognitive development. The research will be presented at the upcoming American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12-19, 2008.

17 Apr 2008

Cutting-edge surgical training facility to open at the University of Sydney

A new facility for the training of the next generation of microsurgeons in both molecular biology and advanced surgical techniques will be officially opened by the Governor of NSW, Her Excellency Professor Marie Bashir AC CVO, at the University of Sydney on Tuesday 22 April.

17 Apr 2008

Purdue's new vaccine under development may provide protection against highly pathogenic bird flu

A new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.

17 Apr 2008