Cell Adhesion News and Research

RSS

Study shows over-expression of adhesion molecules in fat tissues protects mice from obesity, diabetes

Okayama University researchers report that the overexpression of an adhesion molecule found on the surface of fat cells appears to protect mice from developing obesity and diabetes. The findings, published in the journal Diabetes, March 2016, may fuel the development of new therapies targeting these diseases.

9 May 2016

Importance of understanding ovarian cancer on molecular level

Nearly 70 percent of ovarian cancer cases are detected after metastasis, which is the development of secondary malignant growths distant from the primary site of cancer.

6 May 2016

MedUni Vienna researchers identify reason for chemoresistance in small cell lung cancer

Small cell lung cancer is not usually detected until it is at an advanced stage, when metastases have already formed. Chemotherapy is very effective initially but, within a year, cancer recurs and this time does not respond to a course of chemotherapy. The research group headed by Gerhard Hamilton, University Department of Surgery at MedUni Vienna, has now managed to identify the reason for this chemoresistance.

4 Apr 2016

PAH role proposed for left heart failure biomarker

Levels of galectin-3 are elevated in patients with pulmonary arterial hypertension and correlate with disease severity, research shows.

10 Mar 2016

Applying ultrasound therapies for recovery of cardiac stem cells

A joint project of researchers from Universidad Politécnica de Madrid (UPM), Julius Wolff Institute and led by Spanish National Center for Cardiovascular Research shows that when cardiac stem cells undergo low-intensity pulsed ultrasound treatment, these cells can perform continuing modifications, tissue remodeling and regeneration of damaged cardiac tissue after a heart attack.

31 Jan 2016

New study aims to prevent chronic cardiac failure

Researchers at Osaka University clarified that the cell adhesion inhibition of periostin1 damages myocardinal cells, inducing compromised cardiac myocyte contractile force and myocytes death, leading to the onset of cardiac failure after AMI through the administration of periostin neutralizing antibodies they had developed on their own.

26 Jan 2016

Shire announces resubmission of lifitegrast NDA to FDA for treatment of dry eye disease in adults

Shire plc today announced it has resubmitted the New Drug Application (NDA) to the U.S. Food and Drug Administration for its investigational candidate, lifitegrast, for the treatment of signs and symptoms of dry eye disease in adults. Shire resubmitted the NDA in response to the complete response letter (CRL) the company received from the FDA on October 16, 2015.

25 Jan 2016

Researchers trace origins of early abnormal brain overgrowth in ASD

Further underscoring the prenatal origins of Autism Spectrum Disorder (ASD), researchers at University of California, San Diego School of Medicine describe for the first time how abnormal gene activity in cell cycle networks that are known to control brain cell production may underlie abnormal early brain growth in the disorder.

14 Dec 2015

Researchers unveil relationship between ovarian cancer and obesity

Ovarian cancer is a deadly disease, one that's hard to detect until it has progressed significantly. More than 75 percent of women diagnosed with ovarian cancer have metastasis at the time of diagnosis, resulting in a low five-year survival rate of less than 30 percent.

8 Dec 2015

Discovery opens up new avenue for research on potential treatments for Alzheimer's disease

A team of researchers led by UNSW Australia scientists has discovered how connections between brain cells are destroyed in the early stages of Alzheimer's disease - work that opens up a new avenue for research on possible treatments for the degenerative brain condition.

27 Nov 2015

Takeda highlights safety, efficacy of vedolizumab for UC and CD at ACG Annual Scientific Meeting

Takeda Pharmaceuticals, U.S.A., Inc., today announced that data highlighting the efficacy and safety of vedolizumab for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD), will be presented during the 2015 American College of Gastroenterology Annual Scientific Meeting in Honolulu, Hawaii, held on October 16-21.

20 Oct 2015

UConn researchers sequence RNA of most complicated gene

UConn researchers have sequenced the RNA of the most complicated gene known in nature, using a hand-held sequencer no bigger than a cell phone.

From Oxford Nanopore Technologies 12 Oct 2015

Roche to acquire biotechnology company, Adheron Therapeutics

Adheron Therapeutics, a privately held biotechnology company based in Berkeley, California, United States, announced today that it has agreed to be acquired by Roche.

9 Oct 2015

Researchers identify completely new information on how cancer cells internally transmit signals

A new study from the University of Turku, Finland, shows that intracellular receptor signalling sustains cancer cells that have detached from the surrounding tissue. When the signalling is prevented, the cells cannot spread to other parts of the body. This significant research result influences how cancer research is directed in the future.

8 Oct 2015

S. Lawrence Zipursky to receive 2015 Louisa Gross Horwitz Prize from Columbia University

Columbia University will award the 2015 Louisa Gross Horwitz Prize to S. Lawrence Zipursky, PhD, for discovering a molecular identification system that helps neurons to navigate and wire the brain. Zipursky is a professor of biological chemistry at the University of California, Los Angeles and a Howard Hughes Medical Institute investigator.

23 Sep 2015

Mayo Clinic scientists discover potential way to reprogram cancer cells back to normalcy

Cancer researchers dream of the day they can force tumor cells to morph back to the normal cells they once were. Now, researchers on Mayo Clinic's Florida campus have discovered a way to potentially reprogram cancer cells back to normalcy.

25 Aug 2015

New study reveals protein's critical role in development and progression of AML

A new study by researchers at University of California, San Diego School of Medicine reveals a protein's critical - and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.

24 Jul 2015

Researchers identify five recurrent fusion genes involved in acute gastritis and cancer

Studying the gastric cancers of 15 Southeast Asian patients, researchers at The Jackson Laboratory, the Genome Institute of Singapore and other institutions identified five recurrent fusion genes, one of which appears to lead to cellular changes involved in acute gastritis and cancer.

10 Jul 2015

Certain colon cancer genes take a step back to move forward

Recent Weizmann Institute studies are revealing a complex picture of cancer progression in which certain genes that drive tumor growth in the earlier stages get suppressed in later stages - taking a step back to move forward.

1 Jul 2015

Lamont R Jones receives 2015 Research Scholar Award to study pathogenesis of keloids

Lamont R Jones, M.D., vice chair of the Department of Otolaryngology-Head & Neck Surgery at Henry Ford Hospital, received the 2015 Research Scholar Award from the Educational and Research Foundation for the American Academy of Facial Plastic and Reconstructive Surgery to continue his efforts to study the pathogenesis of keloids and improve understanding of how keloid scars develop.

26 Jun 2015