Cell Death News and Research

RSS

Study highlights the potential long-term neurological effects post-COVID-19

Researchers studied the presence of the SARS-CoV-2 spike protein in the skull-meninges-brain (SMB) axis.

10 Apr 2023

Leveraging cell self-destruction to treat glioblastoma tumors

Glioblastoma is the most common type of brain tumor in adults. The disease is 100% fatal and there are no cures, making it the most aggressive type of cancer. Such a poor prognosis has motivated researchers and neurosurgeons to understand the biology of tumors with the goal of creating better therapies.

7 Apr 2023

Chemists discover novel, highly effective anticancer agents with tridimensional structures

A research team co-led by chemists from City University of Hong Kong recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity and the ability to overcome drug resistance in cancer cells.

7 Apr 2023

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict — before treatment begins — how well patients with kidney cancer will respond to immunotherapy, according to new research directed by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

6 Apr 2023

New microfluidic technology enables reliable selection of high-quality sperm for IVF success

Scientists have developed new technology to help couples undergoing in-vitro fertilization (IVF) due to male fertility problems to increase their chances of success in having a baby.

6 Apr 2023

Parkinson's linked to higher levels of pheomelanin in brain: Could it be a biomarker or treatment target?

Researchers discover that the substantia nigra of individuals with Parkinson’s disease had a higher concentration of pheomelanin.

6 Apr 2023

Scientists unearth some of the biological mechanisms behind ferroptosis

A team of researchers at Tohoku University has unearthed some of the biological mechanisms of ferroptosis, a recently discovered type of regulated cell death that is triggered by iron and the accumulation of lipid peroxidation - lipids that have undergone oxidative degeneration.

5 Apr 2023

Candida auris escapes innate immunity through metabolic reprogramming

A team of scientists from Australia and Israel demonstrates that Candida auris, a fungus associated with life-threatening and drug-resistant infections, escapes the host's innate immune response by destroying macrophages through metabolic reprogramming. The fungus is also capable of escaping antimicrobial inflammatory response.

23 Mar 2023

New way to safely, sustainably synthesize a molecule with remarkable anticancer properties

Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value.

23 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

Study discovers a protein controlling resistance to chemotherapy

Despite the recent development of new targeted therapies, chemotherapies remain the most frequently used treatment to treat patients suffering from advanced cancers.

22 Mar 2023

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Researchers at Nagoya University in Japan have identified two enzymes that are involved in macrophage polarization, one of the key factors affecting fibrosis.

22 Mar 2023

Scientists develop a marker for therapy response in acute myeloid leukemia

With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug combination does not work.

17 Mar 2023

Achieving immune cell checkpoint profiling

NewsMedical exchanges with Cerba Research on how to achieve immune cell checkpoint profiling of solid tumors by multiplex immunofluorescence.

From Cerba Research 16 Mar 2023

Study sheds new insight into the dynamics of neural stem cell niche

When it comes to cell types, stem cells have unlimited potential – literally. These self-renewing cells, which are capable of giving rise to any cell type in the body, reside in specialized microenvironments known as niches.

16 Mar 2023

Cuproptosis-associated ferroptosis genes linked with immune infiltration in atherosclerosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. In this study, the authors identify cuproptosis-associated ferroptosis genes in the atherosclerosis microarray of the Gene Expression Omnibus (GEO) database and explored hub gene-mediated immune infiltration in atherosclerosis.

15 Mar 2023

Cell Death News and Research

Study highlights the potential long-term neurological effects post-COVID-19

Leveraging cell self-destruction to treat glioblastoma tumors

Chemists discover novel, highly effective anticancer agents with tridimensional structures

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

New microfluidic technology enables reliable selection of high-quality sperm for IVF success

Parkinson's linked to higher levels of pheomelanin in brain: Could it be a biomarker or treatment target?

Scientists unearth some of the biological mechanisms behind ferroptosis

Candida auris escapes innate immunity through metabolic reprogramming

New way to safely, sustainably synthesize a molecule with remarkable anticancer properties

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Study discovers a protein controlling resistance to chemotherapy

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Scientists develop a marker for therapy response in acute myeloid leukemia

Achieving immune cell checkpoint profiling

Study sheds new insight into the dynamics of neural stem cell niche

Cuproptosis-associated ferroptosis genes linked with immune infiltration in atherosclerosis

New biomimetic model helps study wound healing in burn and laceration wounds

Newly identified small molecule may help treat people with drug-resistant epilepsy

Study sheds new light on a key protein involved in the process of spermiation

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest Life Science News