Cell Migration News and Research

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Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

Okayama University researchers uncover potential new therapeutic target for invasive bladder cancer

Researchers at Okayama University have uncovered a potential new therapeutic target for invasive bladder cancer. The GTP hydrolysing enzyme (GTPase), called Dynamin2, facilitates the rapid invasion of cancer into surrounding tissues; inhibiting its activity could limit the progression of bladder cancer.

10 Jan 2017

Scientists developing magnetic stem cells to fight cancer

Scientists from the Tomsk Polytechnic University's Laboratory of Novel Dosage are developing a technology to control mesenchymal stem cells of patients.

29 Dec 2016

RAGE regulates key signaling pathway that promotes acute and chronic inflammation

Researchers have shown that Receptor for Advanced Glycation End Products helps to regulate a key signaling pathway known to promote both acute and chronic inflammation.

21 Dec 2016

Research finds differences in cell migration between normal and malignant tumor cells

What makes cancer so deadly is its ability to move . The better that doctors can keep tumors contained and protect unaffected organs in the body, the less lethal a cancer will be.

21 Dec 2016

Research shows cellular component may play vital role in how lung cancer spreads

A cellular component known as the Golgi apparatus may play a role in how lung cancer metastasizes, according to researchers at The University of Texas MD Anderson Cancer Center whose findings were reported in the Nov. 21 online issue of the Journal of Clinical Investigation.

21 Nov 2016

GW scientist awarded $2.8 million NIH grant to continue research on corneal wound healing

George Washington University researcher Mary Ann Stepp, Ph.D., received a $2.8 million, five-year R01 grant from the National Institutes of Health to continue her 27 years of research on corneal wound healing.

2 Nov 2016

Carotenoid pigment compound reduces invasiveness of tumors in mouse models of lung cancer

Beta-cryptoxanthin (BCX), a carotenoid pigment compound found primarily in plants, reduces the number and invasiveness of tumors in mouse and cell models of lung cancer, report scientists from the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University.

1 Nov 2016

New type of nanoparticles can deliver chemotherapy efficiently to cancer cells

Engineering researchers at The University of Texas at Austin have developed a new method that delivers chemotherapy directly and efficiently to individual cells.

4 Oct 2016

Cell migration occurs by intermittent bursts of activity, researchers find

Cell migration is a central process in the development and maintenance of multicellular organisms.

29 Sep 2016

Research shows biglycan molecule plays key role in determining tumour malignancy

Researchers at Hokkaido University in Japan have demonstrated that a molecule, called biglycan, plays an intrinsic role in attracting tumour cells toward the inner wall of tumour blood vessels.

14 Jul 2016

Study proves cells can send ephrins and Ephs out to transmit signals

Eph receptors and their partner proteins, the ephrins, are vital for intercellular communication.

8 Jul 2016

Scientists elucidate why acute leukemias with same genetic abnormality vary in aggressiveness

Scientists at the Friedrich Miescher Institute for Biomedical Research and the University of Basel have discovered why acute leukemias with the same genetic abnormality vary in their aggressiveness based on their cellular origin.

24 Jun 2016

Johns Hopkins researchers develop lab test that accurately predicts glioblastoma aggression and spread

Johns Hopkins Medicine researchers report they have developed an experimental laboratory test that accurately clocks the “speed” of human brain tumor cell movement along a small glass “track.”

13 Jun 2016

Maternal immune dysfunction linked to risk of autism with intellectual disability in children

Pregnant women with higher levels of inflammatory cytokines and chemokines, proteins that control communication between cells of the immune system, may be at significantly greater risk of having a child with autism combined with intellectual disability, researchers with the UC Davis MIND Institute have found.

8 Jun 2016

New, easy-to-use method for rapid testing of neutrophil chemotaxis

A team of researchers from the University of Manitoba in collaboration with local clinical scientists in Winnipeg, Canada, have developed a new method for rapid neutrophil chemotaxis test directly from a small drop of whole blood using a microfluidic system.

23 May 2016

Bioprinted 3-D placenta model could help better understand preeclampsia

Preeclampsia is a pregnancy complication involving the placenta that can be serious -- even fatal -- for the mother or fetus. The only effective treatment option is premature delivery.

19 May 2016

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models.

13 May 2016

Novel function of PLK1 gene in prostate cancer metastasis

Researchers at VCU Massey Cancer Center have uncovered a novel function of the gene PLK1 (polo-like kinase 1) that helps prostate cancer cells metastasize (spread) to other parts of the body. This mechanism highlights new potential targets for cancer therapies and challenges the previous understanding of PLK1's role in cancer growth and progression.

22 Apr 2016

BioTek announces launch of Lionheart FX Automated Live Cell Imager

BioTek Instruments announces the launch of the Lionheart™ FX Automated Live Cell Imager with Augmented Microscopy™.

5 Apr 2016