Cell Migration News and Research

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Discovery of protein that may cause breast cancer to spread

In an important finding published online in Developmental Cell , researchers at Albert Einstein College of Medicine of Yeshiva University, along with collaborators at Massachusetts Institute of Technology, have identified a protein likely responsible for causing breast cancer to spread.

8 Dec 2008

Signaling between protein, growth factor is critical for coordinated cell migration

The mysterious process that orchestrates cells to move in unison to form human and animal embryos, heal wounds, and even spread cancer depends on interaction between two well-known genetic signaling pathways, two University of Utah medical school researchers have discovered.

11 Nov 2008

Cold Spring Harbor Protocols features organ and cell culture methods

Understanding the function of organs like the brain, kidney, and reproductive tissues requires experimental systems that allow for the study and manipulation of developing cells and tissues in the laboratory.

4 Nov 2008

Scientists identify a molecule that coordinates the movement of cells

Even cells commute. To get from their birthplace to their work site, they sequentially attach to and detach from an elaborate track of exceptionally strong proteins known as the extracellular matrix. Now, in research to appear in the October 3 issue of Cell, scientists at Rockefeller University show that a molecule, called ACF7, helps regulate and power this movement from the inside - findings that could have implications for understanding how cancer cells metastasize.

2 Oct 2008

Spice-based compound to fight against cancer

Seeking to improve on nature, scientists used a spice-based compound as a starting point and developed synthetic molecules that, in lab settings, are able to kill cancer cells and stop the cells from spreading.

17 Aug 2008

Laboratory and mouse studies show targeted drug blocks the growth of breast cancer cells that spread to the brain

Using laboratory and mouse models of human breast cancer, researchers have found that a small molecule capable of targeting specific proteins on the surface of breast cancer cells can inhibit the growth of breast cancer cells that migrate to the brain.

29 Jul 2008

Noninvasive molecular imaging technology helps track stem cells in tumors

Using noninvasive molecular imaging technology, a method has been developed to track the location and activity of mesenchymal stem cells (MSCs) in the tumors of living organisms, according to researchers at the Society of Nuclear Medicine's 55th Annual Meeting. This ability could lead to major advances in the use of stem cell therapies to treat cancer.

16 Jun 2008

Discovery of gene involved in blood stem cell replication, movement

Researchers at the Joslin Diabetes Center have identified a gene that is responsible for the division and movement of marrow-derived, blood-forming stem cells, a finding that could have major implications for the future of bone marrow and blood cell transplantation.

10 Apr 2008

Researchers identify gene involved in blood stem cell replication, movement

10 Apr 2008

Compound found in soybeans may halt spread of prostate cancer

A compound found in soybeans almost completely prevented the spread of human prostate cancer in mice, according to a study published in the March 15 issue of Cancer Research, a journal of the American Association for Cancer Research.

17 Mar 2008

Brain molecule from endothelial cells may be a new target for treatment of multiple sclerosis

In the February issue of Nature Immunology, the team provides fresh answers concerning the role of novel adhesion molecules in the pathogenesis of MS, a chronic autoimmune disease of the nervous system that affects approximately 55,000 young adults in Canada.

23 Jan 2008

Researchers find new way to block destructive rush of immune cells

Researchers have found a way to selectively block the ability of white blood cells to "crawl" toward the sites of injury and infection when such mobility drives disease, according to a study published today in The Journal of Experimental Medicine.

15 Jan 2008

High blood pressure gene found

Scientists have identified the gene that sets off a sequence of events in the blood vessels of otherwise healthy adults that can lead to high blood pressure.

11 Jan 2008

Small pieces of ribonucleic acid prevent spread of breast cancer

Howard Hughes Medical Institute researchers have identified small pieces of ribonucleic acid (RNA) that suppress the spread of breast cancer to the lungs and bone.

10 Jan 2008

microRNA molecules block breast cancer's ability to spread

Researchers have identified a specific group of microRNA molecules that are responsible for controlling genes that cause breast cancer metastasis.

10 Jan 2008

New understanding of actin networks

Dynamic networks of growing actin filaments are critical for many cellular processes, including cell migration, intracellular transport, and the recovery of proteins from the cell surface.

4 Jan 2008

Protein's new role discovered in autoimmune disease

Investigators at the University of Alabama at Birmingham (UAB) have identified the previously unknown role of a chemical 'messenger' leading to autoimmune disorders like rheumatoid arthritis and lupus.

3 Jan 2008

Protein clue could stop cancer 'creep'

Cancer Research UK scientists have unlocked the secrets of proteins involved in tumour cells creeping away from the original tumour and spreading around the body. Their findings are published in Molecular Cell.

3 Jan 2008

New model of esophageal cancer

In the November 1st issue of G&D, a team of scientists led by Dr. Anil Rustgi (UPENN) presents an innovative new model of esophageal cancer, which holds great promise as an experimental platform to investigate the etiology and possible treatment of this devastating disease.

1 Nov 2007

European project to look at the wiring of the brain during growth

One of the great questions of neurobiology, how the brain is built up during embryonic development, could be resolved by a young French scientist in an award winning project organised by the European Science Foundation (ESF) and the European Heads of Research Councils (EuroHORCS).

24 Sep 2007