Cell Migration News and Research

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Researchers find new way to block destructive rush of immune cells

Researchers have found a way to selectively block the ability of white blood cells to "crawl" toward the sites of injury and infection when such mobility drives disease, according to a study published today in The Journal of Experimental Medicine.

15 Jan 2008

High blood pressure gene found

Scientists have identified the gene that sets off a sequence of events in the blood vessels of otherwise healthy adults that can lead to high blood pressure.

11 Jan 2008

Small pieces of ribonucleic acid prevent spread of breast cancer

Howard Hughes Medical Institute researchers have identified small pieces of ribonucleic acid (RNA) that suppress the spread of breast cancer to the lungs and bone.

10 Jan 2008

microRNA molecules block breast cancer's ability to spread

Researchers have identified a specific group of microRNA molecules that are responsible for controlling genes that cause breast cancer metastasis.

10 Jan 2008

New understanding of actin networks

Dynamic networks of growing actin filaments are critical for many cellular processes, including cell migration, intracellular transport, and the recovery of proteins from the cell surface.

4 Jan 2008

Protein's new role discovered in autoimmune disease

Investigators at the University of Alabama at Birmingham (UAB) have identified the previously unknown role of a chemical 'messenger' leading to autoimmune disorders like rheumatoid arthritis and lupus.

3 Jan 2008

Protein clue could stop cancer 'creep'

Cancer Research UK scientists have unlocked the secrets of proteins involved in tumour cells creeping away from the original tumour and spreading around the body. Their findings are published in Molecular Cell.

3 Jan 2008

New model of esophageal cancer

In the November 1st issue of G&D, a team of scientists led by Dr. Anil Rustgi (UPENN) presents an innovative new model of esophageal cancer, which holds great promise as an experimental platform to investigate the etiology and possible treatment of this devastating disease.

1 Nov 2007

European project to look at the wiring of the brain during growth

One of the great questions of neurobiology, how the brain is built up during embryonic development, could be resolved by a young French scientist in an award winning project organised by the European Science Foundation (ESF) and the European Heads of Research Councils (EuroHORCS).

24 Sep 2007

N-cofilin molecule protects from neuronal disorders

Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly – a form of mental retardation - result from abnormal migration of nerve cells during the development of the brain.

17 Sep 2007

Insight into the role of cancer stem cells in cancer initiation, progression and metastasis

Scientists have identified a distinct subpopulation of cancer stem cells (CSCs) that is responsible for metastasis of a deadly human pancreatic cancer.

13 Sep 2007

Scientists find mechanisms controlling metastasis of breast cancer cells

When cancer cells dissociate from the original tumor and migrate via the blood stream to colonize distant organs, is the main cause of cancer death.

9 Aug 2007

Stem cells enhance hearing recovery

Researchers have shown that bone marrow stem cells injected into a damaged inner ear can speed hearing recovery after partial hearing loss.

26 Jun 2007

Why NSAIDs damage the tissue that lines the gastrointestinal tract

New versions of drugs like buffered aspirin and Vioxx could produce fewer harmful side effects thanks to research being done at Kansas State University's College of Veterinary Medicine.

23 Jun 2007

Scientists observe cell migration

Johns Hopkins researchers have found a way to directly observe cell migration -- in real time and in living tissue. In a report in Developmental Cell, the scientists say their advance could lead to strategies for controlling both normal growth and the spread of cancer, processes that depend on the programmed, organized movement of cells across space.

14 Jun 2007

New contributor to aggressive cancers

Mutations in the cell adhesion molecule known as integrin alpha 7 (integrin 7) lead to unchecked tumor cell proliferation and a significantly higher incidence in cancer spread, or metastasis, in several cancer cell lines, report researchers at the University of Pittsburgh School of Medicine in a study published in the Journal of the National Cancer Institute.

8 Jun 2007

Scientists have captured on video the intracellular version of a postal delivery service

Reporting in the journal Biochemical and Biophysical Research Communications (BBRC), bioengineering researchers at UC San Diego published videos of a key message-carrying protein called paxillin moving abruptly from hubs of communication and transportation activity on the cell surface toward the nucleus.

3 Jun 2007