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Spanish researchers develop new immunotherapy combination for liver cancer

Spanish researchers at Cima University of Navarra have developed a new immunotherapy combination that improves efficacy in animal models of hepatocellular carcinoma. This is a proof of concept that lays the foundations for the application of this treatment in patients with the most common liver cancer.

1 Jul 2023

New method offers insights into mechanisms of staphylococcal pathogenesis

Nearly one in three people globally unknowingly carries Golden staph, or Staphylococcus aureus, in their nose or on their skin. While the bacterium is harmless to most, it can lead to serious infection and even death if it enters the bloodstream through a cut, surgical wound or catheter.

16 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Study demonstrates that SARS-CoV-2 infection and viral fusogens cause glial and neuronal fusion.

9 Jun 2023

Scientists uncover key molecular culprit in ALS: PEG10 gene implicated in pathogenesis

UBQLN2 dysfunction in ALS leads to elevated PEG10 levels, suggesting a role for retrotransposon activity in the disease. PEG10's nuclear localization alters gene expression involved in axon remodeling, implicating it as a contributing mechanism in ALS.

7 Jun 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

New technique could mechanically enhance glymphatic transport in the mouse brain

Like the lymphatic system in the body, the glymphatic system in the brain clears metabolic waste and distributes nutrients and other important compounds.

16 May 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

From CrestOptics 3 Apr 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Researchers developed spherical hydrogel inhalation for enhanced lung defense to protect against SARS-CoV-2 infections.

13 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

New insights into the release of microplastics from breastmilk storage bags

Researchers from China analyzed the quantity, size, and composition of microplastics and other particle matter released into breastmilk from disposable breastmilk storage bags.

6 Feb 2023

Penn scientists discover a cellular pathway that keeps Ebola virus from exiting human cells

In their evolutionary battle for survival, viruses have developed strategies to spark and perpetuate infection. Once inside a host cell, the Ebola virus, for example, hijacks molecular pathways to replicate itself and eventually make its way back out of the cell into the bloodstream, where it can spread further.

3 Feb 2023

Confocal microscopy News and Research

Spanish researchers develop new immunotherapy combination for liver cancer

New method offers insights into mechanisms of staphylococcal pathogenesis

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Scientists uncover key molecular culprit in ALS: PEG10 gene implicated in pathogenesis

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

New technique could mechanically enhance glymphatic transport in the mouse brain

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

New insights into the release of microplastics from breastmilk storage bags

Penn scientists discover a cellular pathway that keeps Ebola virus from exiting human cells

Study shows improved host health by modulating intestinal microbiota

Study suggests cortical hemorrhage in fetal brain may be associated with COVID-19

Researchers discover new cellular component with importance for the sense of smell

Long-lived Chilean rodent is a useful model of natural sporadic Alzheimer's Disease

Multiscale landscaping of droplet wettability and mobility of N95 masks

Can SARS-CoV-2 be inactivated by resonance caused by sound waves at the ultrasound frequency?

Life Science Microscopy eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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