DNA Replication News and Research

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DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "semiconservative" in that each strand of the original double-stranded DNA molecule serves as template for the reproduction of the complementary strand. Hence, following DNA replication, two identical DNA molecules have been produced from a single double-stranded DNA molecule. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication.
Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

UBR7 protein acts as a histone chaperone during DNA replication, study finds

UBR7 protein acts as a histone chaperone during DNA replication, study finds

A Day in the Life of A Clinical Geneticist

A Day in the Life of A Clinical Geneticist

Researchers use gene-editing to create single sex mice litters

Researchers use gene-editing to create single sex mice litters

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

Finding potential biomarkers to predict response to immunotherapy in nonhypermutated cancers

Finding potential biomarkers to predict response to immunotherapy in nonhypermutated cancers

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Scientists develop a single-cell chromatin atlas for the human genome

Scientists develop a single-cell chromatin atlas for the human genome

Protein plays a previously unknown role in halting cell cycle in response to stressful conditions

Protein plays a previously unknown role in halting cell cycle in response to stressful conditions

Machine learning approach effective in predicting antibiotic resistance spread

Machine learning approach effective in predicting antibiotic resistance spread

Aging may not be due to build-up of mutations alone, study suggests

Aging may not be due to build-up of mutations alone, study suggests

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Rice lab receives NIH grant to unravel DNA’s secrets

Rice lab receives NIH grant to unravel DNA’s secrets

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

New insights on replication-stress sensitivity in breast cancer cells

New insights on replication-stress sensitivity in breast cancer cells

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

USP7 inhibitors could increase the anticancer effects of CDK1 compounds in cancer patients

USP7 inhibitors could increase the anticancer effects of CDK1 compounds in cancer patients

Japanese–European scientists detect novel genetic mitochondrial disorder

Japanese–European scientists detect novel genetic mitochondrial disorder

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works