DNA Replication News and Research

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DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "semiconservative" in that each strand of the original double-stranded DNA molecule serves as template for the reproduction of the complementary strand. Hence, following DNA replication, two identical DNA molecules have been produced from a single double-stranded DNA molecule. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication.
Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

New insights on replication-stress sensitivity in breast cancer cells

New insights on replication-stress sensitivity in breast cancer cells

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

USP7 inhibitors could increase the anticancer effects of CDK1 compounds in cancer patients

USP7 inhibitors could increase the anticancer effects of CDK1 compounds in cancer patients

Japanese–European scientists detect novel genetic mitochondrial disorder

Japanese–European scientists detect novel genetic mitochondrial disorder

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

Underrepresentation in genomic databases may affect therapy selection for minority patients

Underrepresentation in genomic databases may affect therapy selection for minority patients

Critical mechanism allows deadly bacteria to gain resistance to antibiotics

Critical mechanism allows deadly bacteria to gain resistance to antibiotics

Study demonstrates the impact of 'reverse antibiotic' on gram-negative bacteria

Study demonstrates the impact of 'reverse antibiotic' on gram-negative bacteria

Study: Interbacterial toxins may contribute to bacterial genetic diversity

Study: Interbacterial toxins may contribute to bacterial genetic diversity

Study: Quantum mechanics plays a role in biological processes and causes mutations in DNA

Study: Quantum mechanics plays a role in biological processes and causes mutations in DNA

Scientists examine DNA repair pathways and their impact on cancer evolution

Scientists examine DNA repair pathways and their impact on cancer evolution

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

Wistar researchers discover new enzymatic function of the Epstein-Barr Virus protein

Wistar researchers discover new enzymatic function of the Epstein-Barr Virus protein

New study unravels complete sequence of DNA repair mechanism

New study unravels complete sequence of DNA repair mechanism

Researchers develop a technique to modify biological polymers with protein-based biochemical messages

Researchers develop a technique to modify biological polymers with protein-based biochemical messages

Study highlights the far-reaching effects of mutagenic compounds on human health

Study highlights the far-reaching effects of mutagenic compounds on human health

Discovery of protein function could be important for future chemotherapy treatment

Discovery of protein function could be important for future chemotherapy treatment