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Prenatal exposure to valproate may increase risk of autism in children

Investigators in a population-based study in Denmark reporting today at the American Epilepsy Society's 65th annual meeting have found there is an increased risk of autism spectrum disorder and childhood autism in children born of mothers who are exposed to the anticonvulsant valproate during pregnancy.

6 Dec 2011

Fetal exposure to valproate impairs IQ till age six

Researchers in the U.S. and U.K. are conducting an ongoing investigation of the cognitive effect of fetal exposure across four commonly used antiepileptic drugs (AEDs) as part of an NIH-funded Neurodevelopmental Effects of Antiepileptic Drugs (NEAD) Study. An early NEAD analysis found that fetal exposure to valproate impairs IQ at age three.

6 Dec 2011

Cayetano Heredia, UT Southwestern sign five-year affiliation agreement

UT Southwestern Medical Center and the Universidad Peruana Cayetano Heredia in Peru have signed a five-year affiliation agreement that establishes an exchange program for medical students and related educational opportunities.

6 Dec 2011

EMBL-EBI, BBSRC welcome UK funding announcement on behalf of life science community

The European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) and the Biotechnology and Biological Sciences Research Council (BBSRC) warmly welcome today's announcement from the UK Government of a £75 million commitment from the Department for Business, Innovation and Skills' Large Facilities Capital Fund (LFCF) for the ELIXIR research infrastructure.

6 Dec 2011

Aspirin decreases risk of major complications from cardiac surgery

Aspirin taken within five days of cardiac surgery is associated with a significant decrease in the risk of major postoperative complications, including renal failure, a lengthy intensive care unit stay and even early death (30-day mortality), according to a study by researchers at Thomas Jefferson University and UC Davis Medical Center set to appear in the journal Annals of Surgery.

6 Dec 2011

Premier healthcare alliance awards new agreement for specialty distribution-research

The Premier healthcare alliance today announced a new agreement for specialty distribution-research has been awarded to VWR International, LLC, a global laboratory supply and distribution company with worldwide sales in excess of $3.6 billion in 2010.

5 Dec 2011

Moffitt investigators to participate with 16 oral and 50 posters presentations at 53rd ASH meeting

When the American Society of Hematology convenes its 53rd Annual Meeting and Exposition on Dec. 10-13 in San Diego, Calif., researchers from Moffitt Cancer Center will break a new record for Moffitt participants with one plenary presentation, 16 oral presentations and more than 50 poster presentations on new research results in a variety of meeting programs that focus on blood cancer basic science and clinical applications, including bone marrow transplantation and clinical trials results.

5 Dec 2011

Scientists discover new candidate gene for Dravet syndrome

Dravet syndrome is a severe genetic epilepsy that appears early in life. About 75 percent of cases can be attributed to mutations in the SCN1A gene encoding the sodium channel NaV1.1. The remaining patients with this syndrome are without a definitive molecular genetic diagnosis. Research presented today at the American Epilepsy Society's 65th Annual Meeting has found a non-SCN1A candidate gene and suggests that Dravet syndrome may be caused by any one of a number of yet unidentified genes.

5 Dec 2011

Epilepsy patients can benefit from gamma knife radiosurgery

Neurosurgeons continue to explore minimally invasive surgery with gamma radiation (gamma knife surgery / GKS) in the treatment of brain lesions causing seizures and epilepsy. Studies of the procedure are showing it to be an effective alternative to invasive microsurgery for hypothalamic hamartomas and other lesions that lie deep within the brain.

5 Dec 2011

Study: 3D-TV may cause seizures in children and adolescents

Certain visual patterns and flashing images can provoke seizures in susceptible individuals, particularly among children and adolescents. Some media reports on the recent introduction of 3D-television sets suggest that this new technology may cause seizures in some viewers.

5 Dec 2011

Potential medical and social barriers to resective epilepsy surgery in patients after initial evaluation

Epilepsy surgery is safe, effective and often curative in selected candidates. Although candidates for epilepsy surgery in the United States are estimated between 100,000 and 200,000, fewer than 5,000 such surgeries are conducted each year. The cause of this disparity is multi-factorial, including an unexplained low level of referrals by physicians and choices made by patients themselves.

5 Dec 2011

Hypothalamus may be involved in generating laughter

Anecdotal evidence suggests that the hypothalamus, a structure lying deep within the brain may be involved in generating laughter. Gelastic epilepsy, a rare condition characterized by laughing seizures, is commonly the result of a congenital brain lesion within the hypothalamus.

5 Dec 2011

U-M scientists generate Dravet-derived neurons

Scientists investigating the fundamental cause of Dravet syndrome, a severe childhood epilepsy, have reprogrammed fibroblasts, a type of skin cell, from Dravet patients and generated patient-specific neurons.

5 Dec 2011

Bromide shows promise against SCN1A-associated Dravet syndrome with intractable seizures

In the mid-nineteenth century Charles Locock, physician to Queen Victoria, introduced bromide as the first effective treatment for epilepsy. The drug was little used in treating the disorder until 1868, however, when its efficacy against seizures was first demonstrated in a clinical trial. Bromide was the sole anticonvulsant available until 1912 and the introduction of phenobarbital.

5 Dec 2011

American Society of Hematology 2012 Scholar Awards announced

The American Society of Hematology (ASH) announces the recipients of its 2012 Scholar Awards. The ASH Scholar Awards provide monetary support for fellows and junior faculty pursuing research careers to assist them during the critical period in which they must complete their training and achieve status as an independent investigator.

3 Dec 2011

Obesity significantly affects personal finances

A new report from The George Washington University School of Public Health and Health Services' Department of Health Policy (GW) uncovered an overall wage differential between those of normal weight and those who are obese, especially when it comes to women. The research, released today, demonstrates the impact obesity may have on a person's paycheck.

3 Dec 2011

Two-thirds of women with catamenial epilepsy have diagnosis of partial epilepsy, study finds

In women of childbearing age with epilepsy, seizure exacerbation may occur either at the time of menstruation or ovulation. Investigators in a specialized epilepsy center have analyzed the data on a group of patients with seizures associated with their menstrual cycles (catamenial seizures) for type of epilepsy, seizure frequency, response to medication, neuroimaging findings, and seizures during pregnancy.

3 Dec 2011

Research roundup: Recession's big impact on men's insurance coverage

Researchers examined three sets of surveillance data and found that of the estimated 1.2 million persons in the United States living with the human immunodeficiency virus, 942,000 persons were aware of their infection. More than three-quarters of those were "linked to care" and among HIV-infected adults in care, "45 percent received prevention counseling, and 89 percent were prescribed antiretroviral therapy."

3 Dec 2011

Most older drivers don't plan for the future when they may be unable to drive safely

Florida is home to one of the highest percentages of residents ages 65 and older in the United States, but very few of them have thought ahead to a time when they will no longer be able to drive a vehicle safely or considered how they will get around without a car, according to a new survey developed by Florida State University and the Florida Department of Transportation.

3 Dec 2011

New rapid blood test for early diagnosis of cryptococcosis

Research conducted at University of Nevada, Reno and licensed through the University's Technology Transfer Office is featured in the technology transfer publication "Better World Report" for a remarkable second year in a row.

3 Dec 2011

Education News and Research

Prenatal exposure to valproate may increase risk of autism in children

Fetal exposure to valproate impairs IQ till age six

Cayetano Heredia, UT Southwestern sign five-year affiliation agreement

EMBL-EBI, BBSRC welcome UK funding announcement on behalf of life science community

Aspirin decreases risk of major complications from cardiac surgery

Premier healthcare alliance awards new agreement for specialty distribution-research

Moffitt investigators to participate with 16 oral and 50 posters presentations at 53rd ASH meeting

Scientists discover new candidate gene for Dravet syndrome

Epilepsy patients can benefit from gamma knife radiosurgery

Study: 3D-TV may cause seizures in children and adolescents

Potential medical and social barriers to resective epilepsy surgery in patients after initial evaluation

Hypothalamus may be involved in generating laughter

U-M scientists generate Dravet-derived neurons

Bromide shows promise against SCN1A-associated Dravet syndrome with intractable seizures

American Society of Hematology 2012 Scholar Awards announced

Obesity significantly affects personal finances

Two-thirds of women with catamenial epilepsy have diagnosis of partial epilepsy, study finds

Research roundup: Recession's big impact on men's insurance coverage

Most older drivers don't plan for the future when they may be unable to drive safely

New rapid blood test for early diagnosis of cryptococcosis

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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