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Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Study examines the efficacy of anastrozole in preventing breast cancer in postmenopausal women at high risk, focusing on the role of baseline estradiol levels and their impact on treatment outcomes.

7 Dec 2023

Novel mechanism leads to motor neuron degeneration in spinal muscular atrophy

The lab of Yongchao C. Ma, PhD, at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago uncovered a novel mechanism that leads to motor neuron degeneration in spinal muscular atrophy (SMA).

7 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

Optibrium’s Quantum Mechanics and Machine Learning Methods Predict Routes of Drug Metabolism

Peer-reviewed study published in Xenobiotica describes an innovative new method that predicts the routes and products of Phase I and II metabolism with high sensitivity and greater precision than other approaches.

From Optibrium Ltd. 7 Dec 2023

Arxspan BioDrive: A Versatile Solution for Molecular Biology

In this interview, NewsMedical speaks to Arxspan about its new all-in-one solution for molecular biology.

From Arxspan 5 Dec 2023

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

The safety, efficacy, and immunogenicity of a mRNA-based vaccine.

5 Dec 2023

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

A group of authors critically evaluated and interpreted the evidence linking mitochondrial dysfunction and metabolic changes to the pathogenesis of Alzheimer's disease (AD).

5 Dec 2023

Omicron infection linked to brain structure changes in men, study finds

Study reveals that men infected with the SARS-CoV-2 Omicron variant experience changes in brain structure, including reduced gray matter thickness and subcortical nuclear volume. These findings, based on MRI data and clinical symptoms, highlight the neurological impact of Omicron infection, contributing to our understanding of COVID-19's effects on the brain.

4 Dec 2023

Study reveals G6PD deficiency linked to higher ADHD risk and increased use of stimulant medications

The risk of Attention Deficit/Hyperactivity Disorder (ADHD) among glucose 6-phosphate dehydrogenase (G6PD)-deficient individuals.

1 Dec 2023

Study reveals differences in SARS-CoV-2 entry mechanisms between humans and mink

Some viruses move between species. For example, SARS-CoV-2, the virus that causes COVID-19, can spill over from humans to mink, an agricultural species, and then spill back from mink to humans.

29 Nov 2023

Unveiling a new cardiac myosin inhibitor through AI-driven virtual screening

Discovery of a novel cardiac-specific myosin modulator.

28 Nov 2023

Potential breakthrough in breast cancer: Five proteins identified as risk markers

Researchers used a Mendelian randomization approach to conduct a genetic association analysis of the levels of over 3,000 proteins to identify biomarkers for early breast cancer detection.

28 Nov 2023

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Dietary components that impact anti-tumor immunity.

28 Nov 2023

Two kiwi fruit every day safe and can replace vitamin C supplementation

Study investigates the health effects of consuming two kiwifruits daily for six weeks. It finds no significant changes in metabolic and inflammatory biomarkers, indicating that regular kiwifruit consumption is safe and increases dietary vitamin C intake without adversely affecting metabolic health.

27 Nov 2023

New study shows Spirulina and high-intensity training combo reduces obesity complications in men

The effects of combining high-intensity interval training (HIIT) with spirulina supplements to mitigate cardiometabolic disease risk.

27 Nov 2023

The future of functional foods: Leveraging Dendrobium officinale for optimal gut health and disease prevention

The structure, extraction, health benefits, and mechanisms of Dendrobium officinale polysaccharides (DOPs).

27 Nov 2023

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Research reveals how a fiber-free diet in Exclusive Enteral Nutrition (EEN) helps treat Crohn's disease in children by affecting the intestinal pathobiont Mucispirillum schaedleri. It shows that this diet alters gut microbiota, reducing Mucispirillum's pathogenicity and aiding in managing colitis.

26 Nov 2023

New insights into how SARS-CoV-2 evades our immune system

This review in Cellular and Molecular Immunology delves into the innate immune response to SARS-CoV-2, exploring how the virus evades immunity and the potential role of innate immunity in long-COVID and vaccine responses, shedding light on future therapeutic strategies.

23 Nov 2023

Researchers identify potential new drug target for treating Barth syndrome

In a Nature Metabolism paper published today, researchers from the University of Pittsburgh detail a potential new target and a small-molecule drug candidate for treating Barth syndrome, a rare, life-threatening and currently incurable genetic disease with devastating consequences.

23 Nov 2023

Saliva analysis breakthrough: Detecting cognitive decline stages in Parkinson’s patients

Researchers used integrative metaproteogenomic analysis to show that changes in salivary microbiota and biomolecules can indicate cognitive impairment stages in Parkinson’s disease patients, offering a potential diagnostic tool.

23 Nov 2023

Enzyme News and Research

Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Novel mechanism leads to motor neuron degeneration in spinal muscular atrophy

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Optibrium’s Quantum Mechanics and Machine Learning Methods Predict Routes of Drug Metabolism

Arxspan BioDrive: A Versatile Solution for Molecular Biology

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

Omicron infection linked to brain structure changes in men, study finds

Study reveals G6PD deficiency linked to higher ADHD risk and increased use of stimulant medications

Study reveals differences in SARS-CoV-2 entry mechanisms between humans and mink

Unveiling a new cardiac myosin inhibitor through AI-driven virtual screening

Potential breakthrough in breast cancer: Five proteins identified as risk markers

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Two kiwi fruit every day safe and can replace vitamin C supplementation

New study shows Spirulina and high-intensity training combo reduces obesity complications in men

The future of functional foods: Leveraging Dendrobium officinale for optimal gut health and disease prevention

Fiber-free diet key to treating childhood Crohn's disease, new study finds

New insights into how SARS-CoV-2 evades our immune system

Researchers identify potential new drug target for treating Barth syndrome

Saliva analysis breakthrough: Detecting cognitive decline stages in Parkinson’s patients

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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