Gene Silencing News and Research

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Researchers employ nucleotide-based gene silencing to mitigate common ataxia

Researchers employ nucleotide-based gene silencing to mitigate common ataxia

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Sylentis presents clinical study results of new treatment for dry eye syndrome

Sylentis presents clinical study results of new treatment for dry eye syndrome

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Researchers target telomerase for killing NRAS-mutant melanoma cells

Researchers target telomerase for killing NRAS-mutant melanoma cells

Study reveals key function of ALS-linked protein

Study reveals key function of ALS-linked protein

New understanding of how molecules regulate enzyme could lead to potential cancer targets

New understanding of how molecules regulate enzyme could lead to potential cancer targets

Newly described super-silenced DNA reveals novel approach to reprogram cells

Newly described super-silenced DNA reveals novel approach to reprogram cells

MGH study points toward potential strategy for treating X-linked disorders

MGH study points toward potential strategy for treating X-linked disorders

Texas Biomedical Research Institute tests promising new treatment for HBV infection

Texas Biomedical Research Institute tests promising new treatment for HBV infection

UAB researchers reveal key role for RSF1 protein in silencing genes

UAB researchers reveal key role for RSF1 protein in silencing genes

Long non-coding RNAs could represent novel male infertility drug targets

Long non-coding RNAs could represent novel male infertility drug targets

New imaging approach reveals dynamic and structural interactions of DNA in cell's nucleus

New imaging approach reveals dynamic and structural interactions of DNA in cell's nucleus

Study uncovers potential new therapeutic targets for HCV infections

Study uncovers potential new therapeutic targets for HCV infections

New gene-silencing drugs cut cholesterol levels by half in early research

New gene-silencing drugs cut cholesterol levels by half in early research

KAUST researchers develop biocompatible nanostructures for use in gene delivery

KAUST researchers develop biocompatible nanostructures for use in gene delivery

Researchers find switch that helps restore damaged axons

Researchers find switch that helps restore damaged axons

Novel dual molecular tuner offers easy way to perform in-depth analyses in mammalian cells

Novel dual molecular tuner offers easy way to perform in-depth analyses in mammalian cells