Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Moffitt researchers develop genetic test that analyzes sensitivity of tumors to radiation therapy

Recent advances in the understanding of cancer have led to more personalized therapies, such as drugs that target particular proteins and tests that analyze gene expression patterns in tumors to predict a patient's response to therapy.

24 Jul 2015

UC San Diego researchers identify pivotal player in diabetic kidney disease

Tapping the potential of metabolomics, an emerging field focused on the chemical processes of metabolism, researchers at University of California, San Diego School of Medicine have identified a new and pivotal player in diabetic kidney disease.

23 Jul 2015

Adaptimmune’s NY-ESO-1 TCR-engineered T-cell therapy mediates sustained antitumor effects in multiple myeloma patients

Adaptimmune Therapeutics plc, a clinical stage biopharmaceutical company focused on the use of T-cell therapy to treat cancer, today announced that data from its Phase I/II study of its affinity enhanced T-cell receptor therapeutic targeting the NY-ESO-1 cancer antigen in patients with multiple myeloma has been published in Nature Medicine.

22 Jul 2015

RepliCel obtains two important approvals to conduct RCS-01 phase 1 human clinical trial

RepliCel Life Sciences Inc., a clinical stage regenerative medicine company focused on the development of autologous cell therapies, today announced it has received two important approvals required to conduct its RCS-01 phase 1 human clinical trial.

21 Jul 2015

Patients' own genetically engineered immune cells show significant success against multiple myeloma

In recent years, immunotherapy has emerged as a promising treatment for certain cancers. Now this strategy, which uses patients' own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable.

21 Jul 2015

Study findings provide basis for potential development of new methods to control HIV infection

Lower levels of cholesterol in certain immune cells--a result of enhanced cholesterol metabolism within those cells--may help explain why some HIV-infected people are able to naturally control disease progression, according to research that will be presented in a poster at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015) in Vancouver, Canada, and the pre-conference 2015 Towards an HIV Cure Symposium.

20 Jul 2015

Virginia Tech scientist uses mathematical model to show how bacteria can control behavior of robots

Forget the Vulcan mind-meld of the Star Trek generation -- as far as mind control techniques go, bacteria is the next frontier. In a paper published July 16 in Scientific Reports, which is part of the Nature Publishing Group, a Virginia Tech scientist used a mathematical model to demonstrate that bacteria can control the behavior of an inanimate device like a robot.

17 Jul 2015

TSRI scientists awarded two grants to develop new therapeutic target to reduce latent HIV infection

Scientists from the Florida campus of The Scripps Research Institute have been awarded a pair of grants totaling nearly $2.8 million from the National Institute of Allergy and Infectious Diseases of The National Institutes of Health to develop a new therapeutic agent to reduce latent levels of HIV that hide from the immune system in infected individuals.

17 Jul 2015

Study shows that 14-3-3 sigma opposes, reverses tumor-promoting metabolic programs

Every parent knows the maxim "feed a cold, starve a fever." In cancer, however, exactly how to feed or starve a tumor has not been easy to determine.

16 Jul 2015

Salk researchers move one step closer to making cures for genetic diseases a reality

Healthy brain, muscle, eye and heart cells would improve the lives of tens of thousands of people around the world with debilitating mitochondrial diseases. Now, researchers at the Salk Institute have gotten one step closer to making such cures a reality: they've turned cells from patients into healthy, mutation-free stem cells that can then become any cell type.

16 Jul 2015

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

The Salk Institute today announced that Rusty Gage, Salk professor in the Laboratory of Genetics, has been selected as one of five recipients of the Paul G. Allen Family Foundation's Allen Distinguished Investigator (ADI) program and will be awarded $1.5 million to conduct his research. These researchers have projects aimed at uncovering the elusive biological foundations of Alzheimer's disease.

15 Jul 2015

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

The Paul G. Allen Family Foundation announced today the award of Allen Distinguished Investigator (ADI) grants to five teams of researchers with projects that will open new and innovative avenues of research in Alzheimer's disease by uncovering its elusive biological roots.

14 Jul 2015

Novel gene therapy control system regulates expression of therapeutic transgenes

Korean researchers have described a novel control system to regulate the expression of a therapeutic transgene by targeting the passenger strand of a microRNA (miR-122) linked to the transgene.

14 Jul 2015

New understanding of keratin 17 protein could lead to development of better ways to prevent cancer

New research from the Johns Hopkins Bloomberg School of Public Health suggests that the protein keratin 17 - the presence of which is used in the lab to detect and stage various types of cancers - is not just a biomarker for the disease, but may play a critical role in tumor growth.

14 Jul 2015

Study discovers potential link between inherited genome-wide DNA sequences and CAD

A study to examine recessively inherited genome-wide DNA sequences has for the first time discovered a potential link with Britain's biggest killer - Coronary Artery Disease (CAD).

10 Jul 2015

Four young scientists named recipients of Damon Runyon-Sohn Pediatric Cancer Research Fellowship Award

The Damon Runyon Cancer Research Foundation has named four outstanding young scientists as recipients of the prestigious Damon Runyon-Sohn Pediatric Cancer Research Fellowship Award, committing nearly $875,000 to help address a critical shortage of funding for pediatric cancer research.

10 Jul 2015

Chromosomal abnormalities in embryos created for IVF can be predicted at earliest stage of human development

Scientists at Oregon Health & Science University, Stanford University, University of Valencia and IGENOMIX have discovered that chromosomal abnormalities in human embryos created for in vitro fertilization, or IVF, can be predicted within the first 30 hours of development at the cell-1 stage which results from the union of a female egg and male sperm.

8 Jul 2015

MU scientists develop RNAMiner tool to make genetic science easier

Technology rapidly is advancing the study of genetics and the search for causes of major diseases. Analysis of genomic sequences that once took days or months now can be performed in a matter of hours. Yet, for most genetic scientists, the lack of access to computer servers and programs capable of quickly handling vast amounts of data can hinder genetic advancements.

8 Jul 2015

UC researcher awarded NCI grant to study effect of MED1 protein on HER2-positive breast cancer

Xiaoting Zhang, PhD, associate professor in the Department of Cancer Biology at the University of Cincinnati College of Medicine, has received a $1.8 million, five-year, R01 award (R01CA197865) from the National Cancer Institute to continue breast cancer research focusing on the function of the protein MED1 on HER2-positive breast cancer.

8 Jul 2015

Scientists identify mechanism that reveals why stem cells undergo self-renewing divisions

UT Southwestern Medical Center scientists collaborating with University of Michigan researchers have found a previously unidentified mechanism that helps explain why stem cells undergo self-renewing divisions but their offspring do not.

2 Jul 2015

Gene Expression News and Research

Further Reading

Moffitt researchers develop genetic test that analyzes sensitivity of tumors to radiation therapy

UC San Diego researchers identify pivotal player in diabetic kidney disease

Adaptimmune’s NY-ESO-1 TCR-engineered T-cell therapy mediates sustained antitumor effects in multiple myeloma patients

RepliCel obtains two important approvals to conduct RCS-01 phase 1 human clinical trial

Patients' own genetically engineered immune cells show significant success against multiple myeloma

Study findings provide basis for potential development of new methods to control HIV infection

Virginia Tech scientist uses mathematical model to show how bacteria can control behavior of robots

TSRI scientists awarded two grants to develop new therapeutic target to reduce latent HIV infection

Study shows that 14-3-3 sigma opposes, reverses tumor-promoting metabolic programs

Salk researchers move one step closer to making cures for genetic diseases a reality

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

Novel gene therapy control system regulates expression of therapeutic transgenes

New understanding of keratin 17 protein could lead to development of better ways to prevent cancer

Study discovers potential link between inherited genome-wide DNA sequences and CAD

Four young scientists named recipients of Damon Runyon-Sohn Pediatric Cancer Research Fellowship Award

Chromosomal abnormalities in embryos created for IVF can be predicted at earliest stage of human development

MU scientists develop RNAMiner tool to make genetic science easier

UC researcher awarded NCI grant to study effect of MED1 protein on HER2-positive breast cancer

Scientists identify mechanism that reveals why stem cells undergo self-renewing divisions

Sensing a Healthier Future

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Expanding research and clinical options for children with cancer

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