Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Scientists devise new strategy to prevent spread of drug-resistant bacteria

A team of scientists from the University of Oxford, U.K. have taken lessons from Adam Smith and Charles Darwin to devise a new strategy that could one day slow, possibly even prevent, the spread of drug-resistant bacteria. In a new research report published in the March 2011 issue of GENETICS, the scientists show that bacterial gene mutations that lead to drug resistance come at a biological cost not borne by nonresistant strains.

19 Mar 2011

New tool for studying microRNA expression in zebrafish

A new research tool for studying microRNA expression in zebrafish will help researchers study the effects of miRNA on the early development of this model organism and better understand developmental and disease mechanisms in humans, as described in Zebrafish, a peer-reviewed journal published by Mary Ann Liebert, Inc.

18 Mar 2011

Fuz expression critical for craniofacial and tooth development: Study

Today, during the 89th General Session & Exhibition of the International Association for Dental Research, held in conjunction with the 40th Annual Meeting of the American Association for Dental Research and the 35th Annual Meeting of the Canadian Association for Dental Research, lead researcher Z. Zhang will hold an oral presentation on a study titled "Fuz is Essential for Craniofacial and Tooth Development."

18 Mar 2011

Individualized dentritic cell vaccine may increase survival time in patients with glioblastoma

A dendritic cell vaccine personalized for each individual based on the patient's own tumor may increase median survival time in those with a deadly form of brain cancer called glioblastoma, an early phase study at UCLA's Jonsson Comprehensive Cancer Center has found.

18 Mar 2011

Gene therapy for Parkinson’s: It works!

A latest study has shown that gene therapy may be successful in treating the dreaded brain degenerative disease – Parkinson’s disease. Neurologists are hopeful that it could be useful in other neurologic disorders too.

17 Mar 2011

Personalized dendritic cell vaccine may increase median survival in mesenchymal glioblastoma patients

17 Mar 2011

New findings help explain why toxoplasmosis causes serious disease

Providing clues into why the severity of a common parasitic infection can vary greatly from person to person, a new Johns Hopkins study shows that each one of three strains of the cat-borne parasite Toxoplasma gondii sets off a unique reaction in the nerve cells it invades.

15 Mar 2011

WaferGen Biosystems 2010 revenue exceeds guidance

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genomic analysis systems, today reported financial results for the three months and year ended December 31, 2010.

14 Mar 2011

ChronTech initiates ChronVac-C DNA vaccine Phase IIb study against HCV

Inovio Pharmaceuticals, Inc., a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today that its partner, ChronTech Pharma AB, has initiated a Phase IIb clinical study of its ChronVac-C DNA vaccine for hepatitis C virus, delivered by Inovio's proprietary electroporation DNA vaccine delivery technology, in combination with standard of care.

14 Mar 2011

Study to identify drug targets for rheumatoid arthritis patients not responding to anti-TNF therapies

GNS Healthcare, Inc., (GNS) the leading healthcare analytics company focused on enabling personalized medicine to improve human health, today announced the publication of results from a study focused on identifying novel drug targets for the one-third of rheumatoid arthritis patients who do not respond to leading anti-TNF therapies.

11 Mar 2011

Genetic variant contributes to higher risk of lung cancer, increases tendency to smoke more

Norwegian researchers have discovered genes that increase not only one's risk of lung cancer, but perhaps one's urge to smoke as well. Now these researchers are working on developing a blood test for lung cancer.

11 Mar 2011

Fluidigm fourth quarter revenue increases to $10.4 million

Fluidigm Corporation today announced its financial results for the fourth quarter and full year ended December 31, 2010.

9 Mar 2011

Autoimmune response mediated by T lymphocytes may play vital role in pathogenesis of biliary atresia

Biliary atresia (BA) is an inflammatory obliterative cholangiopathy with unknown etiology, leading to progressive fibrosis and cirrhosis. Microarray technology, emerged as an indispensable research tool for gene expression profiling, has been used to study the mechanism underlying BA, and allows the simultaneous analysis of thousands of transcripts within a single experiment.

9 Mar 2011

Study shows how individual cells behave during blood vessel formation

Biologists tend to look at cells in bulk, observing them as a group and taking the average behavior as the norm - the assumption is that genetically identical cells all behave the same way.

8 Mar 2011

Scientist discovers new mechanism for regulation of gene expression

Dr. David Levin, Professor of Molecular & Cell Biology at Boston University Henry M. Goldman School of Dental Medicine and Professor of Microbiology at Boston University School of Medicine discovered recently a novel, evolutionarily conserved mechanism for the regulation of gene expression.

4 Mar 2011

Sangamo's preclinical ZFN-gene modification studies for HIV/AIDS treatment presented at CROI

Sangamo BioSciences, Inc. announced that data from its programs to develop ZFN-based therapeutic approaches for the treatment of HIV/AIDS were discussed in four oral presentations at the 18th Conference on Retroviruses and Opportunistic Infections, held in Boston from February 27 to March 2, 2011.

4 Mar 2011

New study finds liver instead of the brain as source of Alzheimer’s plaques

Unexpected results from a Scripps Research Institute and ModGene, LLC study could completely alter scientists' ideas about Alzheimer's disease—pointing to the liver instead of the brain as the source of the "amyloid" that deposits as brain plaques associated with this devastating condition. The findings could offer a relatively simple approach for Alzheimer's prevention and treatment.

4 Mar 2011

Scientists discover genetic process that may allow ovarian cancer to resist chemotherapy

York University researchers have zeroed in on a genetic process that may allow ovarian cancer to resist chemotherapy.

3 Mar 2011

ASU receives W. M. Keck $1 million grant to build next-generation 3D imaging microscope

The W. M. Keck Foundation has awarded Arizona State University a $1 million grant to the team of scientists led by Deirdre Meldrum, Ph.D., at the Biodesign Institute.

2 Mar 2011

Genetic switch increases blood vessels in skeletal muscle of non-exercising mice

Many people suffer from a devastating condition known as critical limb ischemia (CLI) that can lead to muscle wasting and even amputation. The disease is linked to the blockage of blood flow to the skeletal muscle and current treatment options include rehabilitative exercise and surgical bypass of blood vessels. New preclinical research suggests there may be a way to restore blood supply in skeletal muscle without traditional intervention.

2 Mar 2011

Gene Expression News and Research

Further Reading

Scientists devise new strategy to prevent spread of drug-resistant bacteria

New tool for studying microRNA expression in zebrafish

Fuz expression critical for craniofacial and tooth development: Study

Individualized dentritic cell vaccine may increase survival time in patients with glioblastoma

Gene therapy for Parkinson’s: It works!

Personalized dendritic cell vaccine may increase median survival in mesenchymal glioblastoma patients

New findings help explain why toxoplasmosis causes serious disease

WaferGen Biosystems 2010 revenue exceeds guidance

ChronTech initiates ChronVac-C DNA vaccine Phase IIb study against HCV

Study to identify drug targets for rheumatoid arthritis patients not responding to anti-TNF therapies

Genetic variant contributes to higher risk of lung cancer, increases tendency to smoke more

Fluidigm fourth quarter revenue increases to $10.4 million

Autoimmune response mediated by T lymphocytes may play vital role in pathogenesis of biliary atresia

Study shows how individual cells behave during blood vessel formation

Scientist discovers new mechanism for regulation of gene expression

Sangamo's preclinical ZFN-gene modification studies for HIV/AIDS treatment presented at CROI

New study finds liver instead of the brain as source of Alzheimer’s plaques

Scientists discover genetic process that may allow ovarian cancer to resist chemotherapy

ASU receives W. M. Keck $1 million grant to build next-generation 3D imaging microscope

Genetic switch increases blood vessels in skeletal muscle of non-exercising mice

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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