Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Cellzome, GSK form second major alliance to develop new anti-inflammatory drugs

Cellzome today announced that it has formed a second strategic alliance with GlaxoSmithKline (GSK). This new collaboration gives GSK exclusive access to Cellzome's proprietary Episphere(TM) technology in the emerging field of epigenetics as applied to immunoinflammatory disease. Epigenetic mechanisms play a key role in controlling immune cell differentiation and inflammatory gene expression during an excessive inflammatory response.

10 Mar 2010

ZenBio to be commercial source for popular murine 3T3-L1 cell line

ZenBio announce that they will be a commercial source for the popular murine 3T3-L1 cell line, which has been fundamental in metabolic disease research for 30 years.

10 Mar 2010

Exposure to BPA during pregnancy causes permanent abnormalities in uterus of offspring

Researchers at Yale School of Medicine have discovered that exposure during pregnancy to Bisphenol A (BPA), a common component of plastics, causes permanent abnormalities in the uterus of offspring, including alteration in their DNA. The findings were reported in the March issue of Journal of the Federation of American Societies for Experimental Biology.

8 Mar 2010

Entelos, RegeneMed release iToxFX to screen novel compounds for potential toxicity issues

Entelos, Inc., a simulation and modeling company focused on human health, and RegeneMed, Inc., a tissue-based drug discovery and regenerative medicine company, announced today the release of iToxFX™.

8 Mar 2010

Scientists devise software algorithm to detect medically useful information from whole-blood samples

Scientists at the Stanford University School of Medicine have devised a software algorithm that could enable a common laboratory device to virtually separate a whole-blood sample into its different cell types and detect medically important gene-activity changes specific to any one of those cell types.

8 Mar 2010

Researchers discuss possibility of using food to prevent individual's genes from expressing disease

Personal health recommendations and diets tailored to better prevent diseases may be in our future, just by focusing on genetics.

6 Mar 2010

Scientists succeed in mapping entire network of DNA-binding transcription factors

In a significant leap forward in the understanding of how specific types of tissue are determined to develop in mammals, an international team of scientists has succeeded in mapping the entire network of DNA-binding transcription factors and their interactions. This global network, indicating which factors can combine to determine cell fate, will be published in the March 5 issue of the journal Cell.

6 Mar 2010

68th AAD Annual Meeting reveals science behind skin care

Research presented by P&G Beauty & Grooming scientists at the 68th Annual Meeting of the American Academy of Dermatology (Miami Beach, FL, March 5-9) examines skin care science from multiple perspectives, offering insights into how ingredient formulations, care regimens and gene expressions impact skin condition.

6 Mar 2010

Investigators disprove reports that well-fed children are more vulnerable to dengue virus

A new study led by St. Jude Children's Research Hospital investigators disproves reports that well-fed children are more vulnerable to the dengue virus. Mosquitoes spread the virus, which can cause severe flu-like symptoms and sometimes lethal complications.

5 Mar 2010

Inovio Biomedical introduces new CELLECTRA-SP series of hand-held, cordless electroporation devices

Inovio Biomedical Corporation, a leader in DNA vaccine design, development and delivery, has unveiled its new CELLECTRA®-SP series of hand-held, cordless electroporation devices at the DNA Vaccines 2010 conference being held in New Orleans, LA.

3 Mar 2010

Affymetrix introduces GeneAtlas System for processing arrays and characterizing changes in gene expression

Affymetrix, Inc. today announced the launch of the GeneAtlas™ System, a complete, personal solution for processing Affymetrix arrays and characterizing changes in gene expression in a variety of research applications.

2 Mar 2010

Inovio Biomedical's SynCon preventive DNA vaccine receives approval in Korea for Phase I clinical trial

Inovio Biomedical Corporation, a leader in DNA vaccine design, development and delivery, announced today that its affiliate VGX International Inc. has received approval in Korea to begin a Phase I clinical trial in healthy volunteers for Inovio’s SynCon™ preventive DNA vaccine (VGX-3400) targeting H5N1 avian influenza.

2 Mar 2010

ZyGEM introduces new RNAGEM Tissue RNA extraction kits

ZyGEM Corp. Ltd., a provider of innovative enzyme-based products for DNA and RNA extraction and other life sciences applications, today announced the launch of its new RNAGEM™ Tissue RNA extraction kits. This product represents a significant advance in sample preparation for RNA-based testing and analysis.

2 Mar 2010

$28M grant to examine neural and behavioral profiles of healthy cognitive aging

The Research Partnership in Cognitive Aging, a public-private effort to promote the study of brain function with age, will award up to $28 million over five years to 17 research grants to examine the neural and behavioral profiles of healthy cognitive aging and explore interventions that may prevent, reduce or reverse cognitive decline in older people.

2 Mar 2010

Researchers find gene regulator that plays key role in DS-AMKL

Between 5 and 10 percent of babies with Down syndrome develop a transient form of leukemia that usually resolves on its own. However, for reasons that haven't been clear, 20 to 30 percent of these babies progress to a more serious leukemia known as Down syndrome acute megakaryoblastic leukemia (DS-AMKL), which affects the blood progenitor cells that form red blood cells and platelets.

1 Mar 2010

Precise immune disturbances leading to Coeliac disease: More insight

New research has identified four aspects of immune system disturbance which lead to the development of coeliac disease. Nearly 40 different inherited risk factors which predispose to the disease have now been identified. These latest findings could speed the way towards improved diagnostics and treatments for the autoimmune complaint that affects 1 in 100 of the population, and lead to insights into related conditions such as type 1 diabetes.

28 Feb 2010

iBioLaunch platform technology to be licensed for plant-expressed influenza vaccines project

iBio, Inc. announced today that it has agreed in principle to license its technology, the iBioLaunch™ platform, and provide technology transfer services to G-Con, LLC, a private Texas company, and its affiliates, for the development and manufacture of plant-expressed influenza vaccines at a new facility being constructed in Bryan, Texas. The “GreenVax Project” will show proof of concept for a large-scale vaccine production facility using Nicotiana plants grown hydroponically in a contained environment.

27 Feb 2010

imaGenes GmbH passes certification process to qualify as Roche NimbleGen CSP for DNA Methylation Analysis

Roche NimbleGen is pleased to announce that imaGenes GmbH, located in Berlin, Germany, has passed the certification process to qualify as a Roche NimbleGen Certified Service Provider for DNA Methylation Analysis. imaGenes is a solution provider for functional genomics and proteomics with a comprehensive portfolio of high-quality services for molecular life sciences.

26 Feb 2010

BPA exposure during pregnancy may cause permanent reproduction problems for female offspring

Here's more evidence that "safe" plastics are not as safe as once presumed: New research published online in The FASEB Journal suggests that exposure to Bisphenol A (BPA) during pregnancy leads to epigenetic changes that may cause permanent reproduction problems for female offspring. BPA, a common component of plastics used to contain food, is a type of estrogen that is ubiquitous in the environment.

26 Feb 2010

Regulus Therapeutics, GSK announce new collaboration on microRNA therapeutics targeting microRNA-122

Regulus Therapeutics Inc. today announced the establishment of a new collaboration with GlaxoSmithKline (GSK) to develop and commercialize microRNA therapeutics targeting microRNA-122 in all fields with Hepatitis C Viral infection (HCV) as the lead indication. Under the terms of the new collaboration, Regulus will receive additional upfront and early-stage milestone payments with the potential to earn more than $150 million in miR-122-related combined payments, and tiered royalties up to double digits on worldwide sales of products.

25 Feb 2010

Gene Expression News and Research

Further Reading

Cellzome, GSK form second major alliance to develop new anti-inflammatory drugs

ZenBio to be commercial source for popular murine 3T3-L1 cell line

Exposure to BPA during pregnancy causes permanent abnormalities in uterus of offspring

Entelos, RegeneMed release iToxFX to screen novel compounds for potential toxicity issues

Scientists devise software algorithm to detect medically useful information from whole-blood samples

Researchers discuss possibility of using food to prevent individual's genes from expressing disease

Scientists succeed in mapping entire network of DNA-binding transcription factors

68th AAD Annual Meeting reveals science behind skin care

Investigators disprove reports that well-fed children are more vulnerable to dengue virus

Inovio Biomedical introduces new CELLECTRA-SP series of hand-held, cordless electroporation devices

Affymetrix introduces GeneAtlas System for processing arrays and characterizing changes in gene expression

Inovio Biomedical's SynCon preventive DNA vaccine receives approval in Korea for Phase I clinical trial

ZyGEM introduces new RNAGEM Tissue RNA extraction kits

$28M grant to examine neural and behavioral profiles of healthy cognitive aging

Researchers find gene regulator that plays key role in DS-AMKL

Precise immune disturbances leading to Coeliac disease: More insight

iBioLaunch platform technology to be licensed for plant-expressed influenza vaccines project

imaGenes GmbH passes certification process to qualify as Roche NimbleGen CSP for DNA Methylation Analysis

BPA exposure during pregnancy may cause permanent reproduction problems for female offspring

Regulus Therapeutics, GSK announce new collaboration on microRNA therapeutics targeting microRNA-122

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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