Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Human MicroRNA Panel for gene-expression profiling to be launched by WaferGen Biosystems

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genetic analysis systems, today announced that it will be launching the Human MicroRNA Panel for its innovative service for gene-expression profiling using its SmartChip(TM) Real-Time PCR System.

17 Dec 2009

Ivy Foundation awards nearly $10M for new patient-focused brain cancer research projects

Today, the Ben and Catherine Ivy Foundation (Ivy Foundation), announced that it is funding roughly $10 million for four new patient-focused research projects. As with all Ivy Foundation awards, these projects focus on improving the survival and quality of life for people with brain tumors but also specifically address new strategies to improve treatment development.

16 Dec 2009

Genes work together by huddling in clusters inside nucleus, research reveals

Research from the Babraham Institute has revealed for the first time that genes work together by huddling in clusters inside the nucleus - the information centre of a cell. These findings, published in the online edition of the journal Nature Genetics, represent a paradigm shift in our understanding of how the genome is spatially organised in relation to gene expression.

16 Dec 2009

Preclinical study of Arno Therapeutics' drug candidate AR-42 presented at ASH 2009

Arno Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on oncology therapeutics, today announced the presentation of a poster at the annual American Society of Hematology (ASH) meeting that describes the preclinical activity of Arno’s drug candidate AR-42 against leukemia stem cells (LSCs).

16 Dec 2009

Life Technologies completes previously announced acquisition of BioTrove

Life Technologies Corporation, a provider of innovative life science solutions, today announced that it has completed the previously announced acquisition of BioTrove, Inc. for an undisclosed amount.

16 Dec 2009

Results from five new studies on Genomic Health's Oncotype DX breast cancer test announced

Genomic Health, Inc. today announced results from five new studies on its Oncotype DX® breast cancer test, a multi-gene expression test that physicians currently use to predict the likelihood of chemotherapy benefit and recurrence risk for patients with early-stage breast cancer.

16 Dec 2009

Femta Pharmaceuticals, Lonza Group collaborate in cGMP production of FM101 antibody

Femta Pharmaceuticals and Lonza Group Ltd jointly announce the execution of a manufacturing services agreement to facilitate the development and cGMP manufacturing of FM101. FM101 is a high affinity monoclonal antibody in late pre-clinical development for the treatment of Rheumatoid Arthritis.

15 Dec 2009

Pure populations of immature cells that enable male reproduction isolated and transplanted

Reproductive researchers from the University of Pennsylvania and The Children's Hospital of Philadelphia have succeeded in isolating and transplanting pure populations of the immature cells that enable male reproduction in two species-human spermatogonia and mouse gonocytes. These germline stem cells, taken from testis biopsies, demonstrated viability following transplantation to mouse testes within a controlled laboratory setting.

15 Dec 2009

Tel Aviv University researchers unravel the mysteries of DNA packaging

The RNA "spools" that make up DNA in our genes need careful editing, too. Genes are composed of meaningful sequences, called exons, separated by meaningless junk sections called introns.

15 Dec 2009

Preclinical graft study supports Cytori’s proposed mechanism of action

Cytori Therapeutics reported results from a preclinical cell-enriched fat grafting study supporting the safety and efficacy of Cytori’s method for enriching fat grafts with adipose-derived regenerative cells (ADRCs).

14 Dec 2009

Texas researchers identify new detection method for circulating tumor cells

Circulating metastatic breast cancer cells can lose their epithelial receptors, a process that enables them to travel through the bloodstream undetected, according to research from The University of Texas M. D. Anderson Cancer Center.

14 Dec 2009

Results from clinical survey of Oncotype DX on patients with node-positive breast cancer announced

Genomic Health, Inc. today announced results from a clinical survey evaluating the impact of the Oncotype DX® Recurrence Score® result on physicians' adjuvant treatment recommendations for patients with node-positive, hormone receptor-positive breast cancer.

12 Dec 2009

microRNA-206 plays crucial role in the progression of ALS

miRagen Therapeutics, Inc., a biopharmaceutical company focused on improving patients' lives by developing innovative microRNA-based therapeutics for cardiovascular and muscle disease, today announced the publication of data demonstrating that microRNA-206 (miR-206) plays a crucial role in the progression of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and in neuromuscular synaptic regeneration in mice.

11 Dec 2009

Regulus Therapeutics to host educational webinar about microRNA biology

Regulus Therapeutics Inc., founded by Alnylam Pharmaceuticals, Inc., and Isis Pharmaceuticals, Inc., unveiled plans for an educational webinar about microRNA biology that will highlight several recent exciting discoveries in the field and showcase the therapeutic strategies based on microRNA.

10 Dec 2009

CPRIT awards $2 million grant to study prostate cancer

The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded its initial grant for a First-Time, Tenure Track Faculty Member to the University of Texas Southwestern Medical Center in Dallas.

10 Dec 2009

Scientists identify potential drug development target for epilepsy seizures

A team of scientists from The University of Alabama used worms to reel in information that they hope will lead to a greater understanding of cellular mechanisms that may be exploited to treat epilepsy.

10 Dec 2009

Preliminary data from Phase 2 clinical trial of ZFP Therapeutic program presented

Sangamo BioSciences, Inc. announced today the presentation of preliminary data from the Phase 2 clinical trial of its ZFP Therapeutic(TM) program to develop SB-509 as a treatment for amyotrophic lateral sclerosis (ALS) at a Work in Progress session at the 20th International Symposium on ALS/MND held in Berlin, Germany.

9 Dec 2009

Multi-institutional study identifies potential treatment target for ovarian cancer

A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer. In the December 8 issue of Cancer Cell, the research team describes finding that a gene called MAGP2 - not previously associated with any type of cancer - was overexpressed in papillary serous ovarian tumors of patients who died more quickly. They also found evidence suggesting possible mechanisms by which MAGP2 may promote tumor growth.

9 Dec 2009

Xanthohumol compound may aid in preventing prostate cancer

The natural compound xanthohumol blocks the effects of the male hormone testosterone, therefore aiding in the prevention of prostate cancer.

9 Dec 2009

CombinatoRx presents encouraging results from its A2A and b2AR agonist programs for B-cell malignancies

CombinatoRx, Incorporated today announced that preclinical data from its Adenosine A2A receptor (A2A) and Beta-2 Adrenergic Receptor (b2AR) Agonist oncology programs demonstrated synergistic anti-cancer activity when combined with standard-of-care therapies in multiple myeloma and other B-cell malignancies.

8 Dec 2009

Gene Expression News and Research

Further Reading

Human MicroRNA Panel for gene-expression profiling to be launched by WaferGen Biosystems

Ivy Foundation awards nearly $10M for new patient-focused brain cancer research projects

Genes work together by huddling in clusters inside nucleus, research reveals

Preclinical study of Arno Therapeutics' drug candidate AR-42 presented at ASH 2009

Life Technologies completes previously announced acquisition of BioTrove

Results from five new studies on Genomic Health's Oncotype DX breast cancer test announced

Femta Pharmaceuticals, Lonza Group collaborate in cGMP production of FM101 antibody

Pure populations of immature cells that enable male reproduction isolated and transplanted

Tel Aviv University researchers unravel the mysteries of DNA packaging

Preclinical graft study supports Cytori’s proposed mechanism of action

Texas researchers identify new detection method for circulating tumor cells

Results from clinical survey of Oncotype DX on patients with node-positive breast cancer announced

microRNA-206 plays crucial role in the progression of ALS

Regulus Therapeutics to host educational webinar about microRNA biology

CPRIT awards $2 million grant to study prostate cancer

Scientists identify potential drug development target for epilepsy seizures

Preliminary data from Phase 2 clinical trial of ZFP Therapeutic program presented

Multi-institutional study identifies potential treatment target for ovarian cancer

Xanthohumol compound may aid in preventing prostate cancer

CombinatoRx presents encouraging results from its A2A and b2AR agonist programs for B-cell malignancies

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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