Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Molecule delivery method improves stem cell differentiation

Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease.

10 Apr 2008

Method to deliver molecules within embryonic stem cells improves differentiation

Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease.

10 Apr 2008

A diaphanous control during embryo formation

The research now published in the journal Development shows how Dia mutations in fruit flies embryos result in a serious of defects during morphogenesis (process by which cells differentiate into tissues and structures), including loss of adhesion, abnormal movements and even migration of cells from one tissue to another.

9 Apr 2008

Pregnant mothers' diet linked to baby's obesity

Pregnant and lactating rats fed on a diet of hydrogenated fat during pregnancy and lactation had babies who were fatter than rats fed a normal diet, according to research published in Lipids in Health and Disease.

4 Apr 2008

HDAC inhibitors show potential as therapeutic agents in treating alcoholism

Reshaping of the DNA scaffolding that supports and controls the expression of genes in the brain may play a major role in the alcohol withdrawal symptoms, particularly anxiety, that make it so difficult for alcoholics to stop using alcohol.

3 Apr 2008

A new way to test for lung cancer

Researchers from Boston University School of Medicine have developed a new “clinicogenomic model” to accurately test for lung cancer.

2 Apr 2008

Newly identified gene may prompt pancreas cells to form

Before a pancreas is a pancreas, it?s part of the endoderm, one of three layers of cells in a developing embryo that eventually form its organs.

2 Apr 2008

New breakthrough discovery on TB

Medical scientists from the University of Leicester, together with colleagues from St Georges, University of London, funded principally by the Medical Research Council (MRC) and The Wellcome Trust, have published details of a new breakthrough discovery on TB.

1 Apr 2008

Brain scientist shedding light on learning, memory

Neurons spoke to Dr. Joe Z. Tsien when he was a sophomore college student searching for some meaningful extracurricular activity.

28 Mar 2008

REST protein protects embryonic stem cells' versatility and self-renewal

A protein known as REST blocks the expression of a microRNA that prevents embryonic stem cells from reproducing themselves and causes them to differentiate into specific cell types, scientists at The University of Texas M. D. Anderson Cancer Center report in the journal Nature.

25 Mar 2008

MRI opens up promising new avenues for non-invasive diagnoses and classification of cancer

Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surgery.

25 Mar 2008

Deadly genetic disease prevented before birth in zebrafish with genetic patch

By injecting a customized "genetic patch" into early stage fish embryos, researchers at Washington University School of Medicine in St. Louis were able to correct a genetic mutation so the embryos developed normally.

24 Mar 2008

Neuronal regulators offer potential targets for cancer

Being too brainy can be a bad thing in a junior high cafeteria, where the social hierarchy favors other traits. "Braininess" also causes problems for cells.

20 Mar 2008

More efficient gene targeting improves prospects for gene therapy

The Nobel prize-winning MRC scientist Sir Aaron Klug and a team from an American company, Sangamo BioSciences, have announced a new way to target genes that may revolutionise medical research and pave the way for new treatments.

20 Mar 2008

What change does prokineticin 2/Bv8 have in human hepatocellular carcinoma?

Liver hepatocarcinoma is a highly vascularized cancer, and more and more research is focused on the molecules controlling angiogenesis.

19 Mar 2008

Silencing gene in tobacco plants reduces harmful carcinogens

In large-scale field trials, scientists from North Carolina State University have shown that silencing a specific gene in burley tobacco plants significantly reduces harmful carcinogens in cured tobacco leaves.

19 Mar 2008

Role for microRNAs in limb regeneration

In the March 15th issue of G&D, Dr. Kenneth Poss (Duke University Medical Center) and colleagues reveal that microRNA depletion is a necessary step in tissue regeneration - a discovery with interesting implications for their use in regenerative medicine.

17 Mar 2008

deCODE obesity study sheds light on how genetic factors contribute to major public health problems

In a paper published online in the journal Nature, a team of deCODE scientists detail a major mechanism through which genetic factors contribute to major public health problems.

17 Mar 2008

Damaged veins heal faster with heparin treatment, laboratory study finds

A commonly used medication that prevents blood clots from forming may also prevent existing clots from damaging delicate vein walls and may accelerate healing in a clot-damaged area of vein wall, according to new research from the University of Michigan Cardiovascular Center.

14 Mar 2008