Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Small animal imaging facility is big boon to research

When powerful magnets line up the body's protons before radiofrequency waves can grab their attention away, it's called spin physics.

30 Aug 2007

Researchers chart the level of gene expression in melanoma cell lines

Other than visually inspecting the disease, doctors have no genetic blueprint to classify melanomas, a lethal form of skin cancer.

30 Aug 2007

Gene regulation in humans is closer than expected to simple organisms

Gene networks are some of the most basic features of a living organism. An external or internal stimulus activates some genes, which in turn control others genes whose activity turns on or off various biological processes (such as the cell cycle, energy production, DNA repair, cellular suicide etc).

30 Aug 2007

Researchers discover what makes lymphomas tick

University of Pennsylvania researchers and their colleagues at the Wistar Institute and University of Oxford have discovered the molecular process by which the PAX5 protein, necessary for lymphocyte development, promotes the growth of common lymphomas, thereby unveiling a potential new target in the fight against cancer.

30 Aug 2007

New understanding of factor YY1 in gene expression

The Conaway Lab - led by Joan Conaway, Ph.D., and Ron Conaway, Ph.D., Investigators - has published findings that shed light on the role of the much-studied transcription factor YY1 in gene expression.

28 Aug 2007

Brain function is even more impaired in cirrhotic than non-cirrhotic alcoholics

Sustained exposure to alcohol can cause scarring and dysfunction of the liver, referred to as cirrhosis.

28 Aug 2007

Scientists reveal the actions of a key player in colorectal cancer

Colorectal cancer is one of the most prevalent cancers in the Western world. The tumor starts off as a polyp but then turns into an invasive and violent cancer, which often spreads to the liver.

28 Aug 2007

Smoking turns on genes

Smoking tobacco is no longer considered sexy, but it may prove a permanent turn on for some genes.

26 Aug 2007

New clue to mechanisms of gene signaling and regulation

Scientists have discovered a pattern in the DNA sequence of the mouse genome that may play a fundamental part in the way DNA molecules regulate gene expression.

24 Aug 2007

Discovery of new gene family essential for embryonic development

The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of the development of cancer.

24 Aug 2007

All eukaryotic kinases share 1 common set of substrates

Kinase mediated phosphorylation is generally recognised as the major regulator of virtually all metabolic activities in eukaryotic cells including proliferation, gene expression, motility, vesicular transport and programmed cell death.

24 Aug 2007

Reactivating a critical gene lost in kidney cancer reduces tumor growth

Researchers at Mayo Clinic Jacksonville, have found that a key gene is often silenced in clear cell renal cell carcinoma, the most common type of kidney cancer, and when they restored that gene in human kidney cancer cells in culture and animal experiments, tumors stopped growing and many disappeared.

17 Aug 2007

Green tea for cancer prevention

Concentrated chemicals derived from green tea dramatically boosted production of a group of key detoxification enzymes in people with low levels of these beneficial proteins, according to researchers at Arizona Cancer Center.

13 Aug 2007

New drug targets for multiple myeloma

Research investigators have identified molecular changes in multiple myeloma cells that activate an important biological pathway associated with cell growth and survival, thereby revealing potential new targets for drugs to treat this cancer.

13 Aug 2007

Researchers discover how Bcl-3 protein stops inflammation

Researchers at the University of Pennsylvania School of Medicine recently identified how a regulatory protein called Bcl-3 helps to control the body's inflammation response to infection by interfering a critical biochemical process called ubiquitination.

12 Aug 2007

New insights into cell division process

Which genes are passed on from mother to child is decided very early on during the maturation of the egg cell in the ovary.

12 Aug 2007

Almac Diagnostics announces major study analysing ductal carcinoma in situ tissue samples

Today Almac Diagnostics announced a major study analysing ductal carcinoma in situ tissue samples using its novel Breast Cancer DSA microarray.

9 Aug 2007

Scientists produce functioning neurons from human embryonic stem cells

Scientists with the Institute of Stem Cell Biology and Medicine at UCLA were able to produce from human embryonic stem cells a highly pure, large quantity of functioning neurons that will allow them to create models of and study diseases such as Alzheimer's, Parkinson's, prefrontal dementia and schizophrenia.

8 Aug 2007

Bcl-3 protein regulates inflammation by blocking ubiquitination

8 Aug 2007

New research may lead to future gene therapies for patients with sickle cell anemia and beta-thalassemia

Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.

7 Aug 2007