Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Sensor protein that identifies DNA breaks and activates the p53 cell-death program has been identified

DNA breaks from radiation, toxic chemicals, or other environmental causes occur routinely in cells and, unless promptly and properly repaired, can lead to cancer-causing mutations.

4 Nov 2004

Diabetic or obese patients suffering advanced heart failure have higher levels of fat embedded in their hearts

Heart failure, progressive and potentially fatal weakening of the heart muscle, is associated with both obesity and diabetes, but the mechanisms by which damage occurs are not well-understood, said senior author Heinrich Taegtmeyer, M.D., Ph.D., professor of cardiology.

1 Nov 2004

Micro-array technology is revolutionising current drug development

Gene expression micro-array technology is benefiting all phases of the discovery, development and subsequent use of new cancer therapeutics

29 Oct 2004

Study could lead to new, more effective treatments for urinary tract infections

Anyone who thinks scientists lead a glamorous, exciting life should talk to Jennifer Snyder, a graduate student at the University of Maryland’s School of Medicine.

25 Oct 2004

Genetic predictions may bring “quantum leap” in breast cancer treatment success

Researchers at Virginia Commonwealth University’s Massey Cancer Center received a prestigious award and a $600,000 grant from the V Foundation for Cancer Research, one of the nation’s leading organizations devoted exclusively to funding cancer research.

20 Oct 2004

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Brain cells become increasingly unable to regulate calcium loads as they age, becoming more vulnerable to injury and premature death, according to new findings that Virginia Commonwealth University researchers will present at an international conference this month.

20 Oct 2004

Comprehensive study raises questions about "demethylation" agents

Agents believed to selectively "restart" genes that limit cancer's growth -- a potential treatment option already in early clinical studies -- instead turn off as many genes as they turn on, a team of researchers from the National Cancer Institute and Johns Hopkins has discovered.

18 Oct 2004

Benitec receives exclusive rights to use DNA technology pioneered at Stanford University for all RNAi therapeutic uses

Benitec has announced an exclusive licensing deal with Stanford University. Under the license, Benitec receives exclusive rights to use the Minicircle DNA technology pioneered at Stanford University for all RNAi therapeutic uses, with sub-licensing rights.

18 Oct 2004

Researchers stimulate the body to repair tissue damaged by peripheral arterial obstructive disease

Duke University Medical Center researchers have shown that they can stimulate the body to produce its own naturally occurring growth factors to promote blood vessel growth into tissue damaged by peripheral arterial obstructive disease (PAOD).

13 Oct 2004

Estrogen protects male rats from aortic aneurysms

When it comes to abdominal aortic aneurysms – life-threatening bulges or weak areas in the main artery feeding blood to the lower half of the body – new U-M research shows that it is definitely better to be female.

12 Oct 2004

Dietary iron imbalances increase the odds of developing Parkinson's disease

You might want to toss those iron-fortified vitamins, because absent a diagnosed deficiency too much of a good thing can be bad.

12 Oct 2004

New study offers rare glimpse of how the smallpox virus attacks its victims

Results of a new study in monkeys offer scientists a rare glimpse of how, on a molecular level, the smallpox virus attacks its victims. The findings shed light on how the virus caused mass death and suffering, and will help point the way to new diagnostics, vaccines and drugs that would be needed in the event of a smallpox bioterror incident.

12 Oct 2004

Study sheds light on events orchestrating the changes when mammalian eggs are fertilized and become embryos

A new study sheds light on events orchestrating the changes when mammalian eggs are fertilized and become embryos. Researchers have discovered that expression of genes in mouse eggs and very early embryos is activated in part by regions of DNA called retrotransposons, which may have originated from retroviruses.

11 Oct 2004

University of Florida researchers reveal secret lives of genes during spinal injury

The body attempts to heal a damaged spinal cord in much the same way it repairs skin after simple cuts and scrapes, an insight that may lead to new treatments for the thousands of people paralyzed each year because of spinal cord injuries, say scientists at the University of Florida Health Science Center.

5 Oct 2004

Gene Expression News and Research

Further Reading

Sensor protein that identifies DNA breaks and activates the p53 cell-death program has been identified

Diabetic or obese patients suffering advanced heart failure have higher levels of fat embedded in their hearts

Micro-array technology is revolutionising current drug development

Study could lead to new, more effective treatments for urinary tract infections

Genetic predictions may bring “quantum leap” in breast cancer treatment success

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Comprehensive study raises questions about "demethylation" agents

Benitec receives exclusive rights to use DNA technology pioneered at Stanford University for all RNAi therapeutic uses

Researchers stimulate the body to repair tissue damaged by peripheral arterial obstructive disease

Estrogen protects male rats from aortic aneurysms

Dietary iron imbalances increase the odds of developing Parkinson's disease

New study offers rare glimpse of how the smallpox virus attacks its victims

Study sheds light on events orchestrating the changes when mammalian eggs are fertilized and become embryos

University of Florida researchers reveal secret lives of genes during spinal injury

Significant progress in development of an animal model of smallpox that closely resembles human disease

Artificial neural networks and DNA microarrays to successfully predict clinical outcomes of neuroblastoma patients

First generation of human retinal cells in the laboratory from human embryonic stem cells

Zebrafish atlas will help research community to model human disease

Liver cancer genes cluster into two subsets that correlate to survival

Missing genes may help explain why plague bacteria are so deadly

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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