Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Decoding the differences between two vital RNA transport complexes

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

8 Feb 2024

Enzyme released by immune cells may play role in depression

Mount Sinai researchers have shown for the first time that immune cells called monocytes, derived in the bone marrow and released into the bloodstream, can be drawn during stress into sites in the brain that control emotional behaviors.

8 Feb 2024

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial role in tumor progression.

7 Feb 2024

Immune cell networks key to success of personalized cancer treatment

Through an analysis of tumor samples collected over time from patients with advanced melanoma, a Ludwig Cancer Research study has identified a set of preexisting conditions in tumors that predict whether such patients are likely to respond to a personalized immunotherapy known as adoptive T cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL).

7 Feb 2024

New study sheds light on sex differences in allergic airway inflammation

Researchers explored how sex hormones and chromosomes influence allergic inflammation and gene expression in four-core genotype (FCG) mice exposed to house dust mites (HDMs).

7 Feb 2024

Researchers uncover how deadly MRSA pneumonia inhibits body's antimicrobial activity

Researchers examined how heparan sulfate (HS) shedding impacts cathelicidin efficacy in Methicillin-Resistant Staphylococcus aureus (MRSA) pneumonia.

7 Feb 2024

Researchers develop new approach to improve the accuracy of RNA sequencing

A team at NDORMS, University of Oxford has developed a new approach to significantly improve the accuracy of RNA sequencing.

7 Feb 2024

Extra fingers and double hearts: Scientists decode how tiny mutations can derail development

Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.

6 Feb 2024

Single-cell study reveals clues to epigenetic drug response in Myelodysplastic Syndrome

Researchers from the Josep Carreras Leukaemia Research Institute, spearheaded by the Cancer Epigenetics group led by Dr. Manel Esteller, described the effects of chemotherapy at the single cell resolution in the bone marrow of Myelodysplastic Syndrome patients.

6 Feb 2024

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study demonstrates Resveratrol's ability to mitigate Alzheimer's Disease (AD) symptoms by inhibiting proinflammatory responses and promoting antioxidant enzyme expression in microglial cell lines, offering insights into its neuroprotective mechanisms.

5 Feb 2024

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

Researchers uncover that the Xist ribonucleoprotein complex, unique to females, is a key driver of sex-biased autoimmunity, offering new insights into autoimmune disorders' higher prevalence in women.

4 Feb 2024

Researchers discover mechanism that protects tissue after faulty gene expression

The genetic material, in the form of DNA, contains the information that is crucial for the correct functioning of every human and animal cell.

2 Feb 2024

Study reveals the spatial connectivity patterns of mouse hippocampal neurons

A study published in Science on Feb. 1 reported a comprehensive database of single-neuron projectomes consisting of over 10,000 mouse hippocampal neurons, thus revealing the spatial connectivity patterns of mouse hippocampal neurons at the mesoscopic level.

2 Feb 2024

A promising approach for aging research

In mid-January 2024, the Friedrich Schiller University Jena made an important discovery public: A team of researchers from the universities of Jena and Shenzhen (China), as well as the Jena University Hospital, decoded a molecular mechanism that plays a crucial role in the development of breast cancer.

1 Feb 2024

Study observes rapid immune response in individuals switching to vegan and keto diets

Researchers evaluated the impact of vegan and ketogenic diets on immune response and gut microbiota in humans.

1 Feb 2024

Is there an association between vitamin D, immunocompetence, and aging?

The role of an individual’s immunocompetence in the responsiveness to vitamin D.

1 Feb 2024

Immune protein Ku70 key in fighting bowel cancer

Study establishes Ku70's role in tumor suppression, showing that reduced expression or mutations in this DNA repair protein significantly increase intestinal cancer risk.

30 Jan 2024

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis."

30 Jan 2024

Study unmasks secrets of glioma's invasive margins

High-grade gliomas are cancerous tumors that spread quickly in the brain or spinal cord.

30 Jan 2024

Gut microbiome may hold key to fighting common respiratory viruses

The composition of microbiota found in the gut influences how susceptible mice are to respiratory virus infections and the severity of these infections, according to researchers from the Center for Translational Antiviral Research in the Institute for Biomedical Sciences at Georgia State University.

30 Jan 2024