Gene Transfer News and Research

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Gene Transfer is the insertion of genetic material into a cell.

Debate over safety of gene therapy trials focuses on issue of informed consent

Can a patient who agrees to participate in a safety study of a gene therapy protocol give truly informed consent and understand the risks involved when the consent forms are highly technical and the physician or institution seeking their consent has a stake in the study and its outcome?

23 Jan 2008

Lymphatic vessel and lymph node function are restored with growth factor treatment

The frequent spread of certain cancers to lymph nodes often necessitates surgery or radiation therapy that damages the lymphatic system and can cause lymphedema, a condition of localized fluid retention that often increases susceptibility to infections.

4 Dec 2007

Gene-transfer technique trial for childhood blindness under way

Three decades have passed since gene therapy pioneer William W. Hauswirth, Ph.D., and his colleagues at the University of Florida began work on a virus that could safely deliver corrective genes into living animals.

19 Nov 2007

Massive reanalysis of genome data solves case of the lethal genes

It is better to be looked over than overlooked, Mae West supposedly said. These are words of wisdom for genome data-miners of today.

19 Oct 2007

One species' entire genome discovered inside another's

Scientists at the University of Rochester and the J. Craig Venter Institute have discovered a copy of the entire genome of a bacterial parasite residing inside the genome of its host species.

30 Aug 2007

Scientists tackle gene doping in athletes

Gene doping has the potential to spawn athletes capable of out-running, out-jumping and out-cycling the strongest of champions.

7 Aug 2007

New minimally invasive method of treating cancer

A team of biomedical engineers at Virginia Tech and the University of California at Berkeley has developed a new minimally invasive method of treating cancer, and they anticipate clinical trials on individuals with prostate cancer will begin soon.

9 Jul 2007

Real-time, direct MRI monitoring of vector distribution within the brain

A team of scientists, led by Dr. Krystof Bankiewicz, University of California-San Francisco, presented this significant advance, which allows, for the first time, to adjust parameters of vector infusion while delivering gene therapy, giving surgeon full control over gene transfer technology.

3 Jun 2007

Novel technologies show promise for future of gene transfer

Several new technologies that could significantly impact the future of gene transfer applications were presented at a conference at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

New platform for regulating the expression of therapeutic genes

A new platform for regulating the expression of therapeutic genes, which will have major implications for gene and cell therapy, was presented at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

Could the food we eat be contributing to the continuing rise of antibiotic-resistant infections?

Harmless and even beneficial bacteria that exist in our food supply may also be carrying genes that code for antibiotic resistance.Once in our bodies, could they transmit the resistance genes to disease-causing bacteria?

24 May 2007

Researchers develop way to calculate rate of gene transfer among bacteria in the environment

Scientists from the University of California-Davis recently developed a mathematical model of the rate of gene transfer among bacteria in the environment.

16 May 2007

Gene therapy to treat erectile dysfunction shows promise

The first human study using gene transfer to treat erectile dysfunction (ED) shows promising results and suggests the potential for using the technology to treat overactive bladder, irritable bowel syndrome and asthma, according to the researchers.

2 Dec 2006

New way of delivering corrective genes holds promise for hereditary diseases of the heart

A new way of delivering corrective genes with a single injection into a vein holds promise for long-lasting treatments of hereditary diseases of the heart, University of Florida researchers report.

6 Aug 2006

Transgenic goat's milk could help tackle children's intestinal disease

Milk produced by transgenic goats, which carry the gene for an antibacterial enzyme found in human breast milk, altered the intestinal bacteria in young goats and pigs that were fed the milk.

4 Aug 2006

Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain

Chronic widespread pain, a common medical condition, can be difficult to treat and is often associated with fatigue, poor sleep and depression.

26 Jul 2006

Researchers use proteins to 'switch on' heart tissue repair system

Researchers at the University of Pennsylvania School of Medicine are utilizing a protein to "switch on" the ability to repair damaged heart tissue.

9 Jul 2006

Therapeutic gene suspected to cause cancer

One of the few gene therapy studies that had ever been successful was terminated in 2003, because several of the treated children had developed leukemia.

3 May 2006

New Hybrid virus may aid treatment of cancer

Researchers at The University of Texas M. D. Anderson Cancer Center have created a new class of hybrid virus and demonstrated its ability to find, highlight, and deliver genes to tumors in mice.

26 Apr 2006

First gene therapy human trial in the United States for a form of muscular dystrophy under way

The clinical trial for Duchenne muscular dystrophy (DMD) tests the safety and effectiveness of a therapy that was developed over two decades by scientists at the University of North Carolina Chapel Hill's School of Medicine and the University of Pittsburgh.

16 Apr 2006