Genetic Engineering News and Research

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Genetically modifying zebrafish provides numerous, highly accurate disease models

Research published today describes how zebrafish can be genetically engineered to produce more accurate models of human disease.

18 Oct 2018

Number of VHA facilities offering acupuncture has increased rapidly

Acupuncture is an increasingly important and effective component of chronic pain management and other areas of care in the Veterans Health Administration.

16 Oct 2018

Research points to potential new treatment for hearing loss

Researchers have taken an important step toward what may become a new approach to restore the hearing loss. In a new study, out today in the European Journal of Neuroscience, scientists have been able to regrow the sensory hair cells found in the cochlea - a part of the inner ear - that converts sound vibrations into electrical signals and can be permanently lost due to age or noise damage.

15 Oct 2018

Extension trial assesses benefit of switching from flash monitoring to RT-CGM for hypoglycemia

In follow-up to the I HART CGM study, which showed the benefit of real-time continuous glucose monitoring compared to flash monitoring for time spent in hypoglycemia among adults with type 1 diabetes at high hypoglycemia risk, researchers conducted an extension trial that assessed the effects of continuing RT-CGM or switching from flash to RT-CGM of the subsequent 8 weeks.

15 Oct 2018

Researchers develop two-pronged approach for targeting Ebola virus

In a new study researchers have developed a two-pronged approach for targeting Ebola virus infection using linked nucleic acid (LNA) antisense oligonucleotides (ASOs)designed to interfere both genes essential for translation of Ebola virus genes and to block production of an intracellular human protein needed for the virus to enter cells.

12 Oct 2018

Using pulsed electric fields in cancer therapy

Pulsed electric fields are helping fight cancer, whether by inducing tumor cell death or by stimulating the immune system.

11 Oct 2018

A new way to create customized mouse models for studying brain development

Scientists studying how genetics impact brain disease have long sought a better experimental model. Cultures of genetically-modified cell lines can reveal some clues to how certain genes influence the development of psychiatric disorders and brain cancers.

11 Oct 2018

Carnegie scientist awarded NIH grant to identify novel medicines for cardiovascular disease

Carnegie's Department of Embryology scientist Steven Farber and team have been awarded a 5-year $3.3-million NIH grant to identify novel pharmaceuticals for combatting a host of diseases associated with altered levels of lipoproteins like LDL ("bad cholesterol").

11 Oct 2018

Bridge-like structure within estrogen receptor could serve as new drug target for breast cancer

Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis.

10 Oct 2018

CDC’s Systemic Review analyzes HIV-related stigma among US healthcare providers

A Systemic Review from the U.S. Centers for Disease Control and Prevention analyzed studies of HIV-related stigma among healthcare provider and identified three main themes: attitudes, beliefs, and behaviors; quality of patient care; and education and training.

10 Oct 2018

Researchers devise a simple way to boost efficacy of malarial TBVs

For decades, scientists have been trying to develop a vaccine that prevents mosquitoes from spreading malaria among humans.

9 Oct 2018

'Supercharged' immune cells could help fight cancer

A type of 'supercharged' immune cell could be mass-produced to help fight cancer.

9 Oct 2018

Study suggests novel approach to treating adults with autism spectrum disorder

A team of scientists at Florida Atlantic University has uncovered a brain-signaling pathway that can be pharmacologically manipulated in genetically engineered mice to reverse an autism-related pathway.

8 Oct 2018

DFG publishes new position paper on synthetic biology

Scientific developments in the field of synthetic biology have often given rise to public debate on the possible need for additional regulation. In response, the Permanent Senate Commission on Genetic Research of the Deutsche Forschungsgemeinschaft has published a position paper on synthetic biology, in which it describes key scientific advancements in the field within the context of current public discourse.

8 Oct 2018

Researchers identify neurons essential for normal sleep

Two decades ago, Clifford B. Saper, MD/PhD, Chairman of the Department of Neurology at Beth Israel Deaconess Medical Center, and colleagues discovered a set of nerve cells they thought might be the switch that turns the brain off, allowing it to sleep.

8 Oct 2018

USDA scientist tries to naturally enhance minerals of wheat flours

Is biofortification the best thing since sliced bread? Well, biofortified wheat could certainly make it easier to help some humans get proper nutrition.

3 Oct 2018

Carnegie professor receives NIH Director's New Innovator Award

Kathryn Whitehead, assistant professor of chemical engineering at Carnegie Mellon University, has been awarded a 2018 National Institutes of Health (NIH) Director's New Innovator Award for her project titled "Fate, Function, and Genetic Engineering of Breast Milk Cells for Infant Therapy."

3 Oct 2018

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

New tool provides improved in vivo imaging of atherosclerotic plaque development

Atherosclerosis, involving the buildup of plaque in the arteries and an associated reduction in the flow of blood, is a major feature of cardiovascular diseases.

28 Sep 2018

Genetic Engineering News and Research

Genetically modifying zebrafish provides numerous, highly accurate disease models

Number of VHA facilities offering acupuncture has increased rapidly

Research points to potential new treatment for hearing loss

Extension trial assesses benefit of switching from flash monitoring to RT-CGM for hypoglycemia

Researchers develop two-pronged approach for targeting Ebola virus

Using pulsed electric fields in cancer therapy

A new way to create customized mouse models for studying brain development

Carnegie scientist awarded NIH grant to identify novel medicines for cardiovascular disease

Bridge-like structure within estrogen receptor could serve as new drug target for breast cancer

CDC’s Systemic Review analyzes HIV-related stigma among US healthcare providers

Researchers devise a simple way to boost efficacy of malarial TBVs

'Supercharged' immune cells could help fight cancer

Study suggests novel approach to treating adults with autism spectrum disorder

DFG publishes new position paper on synthetic biology

Researchers identify neurons essential for normal sleep

USDA scientist tries to naturally enhance minerals of wheat flours

Carnegie professor receives NIH Director's New Innovator Award

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Researchers deplete key protein for DNA replication using protein degradation system

New tool provides improved in vivo imaging of atherosclerotic plaque development

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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