Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

GWA Study helps scientists identify genetic variant that increases tuberculosis susceptibility in African populations

Scientists have identified a genetic variant which increases susceptibility to tuberculosis (TB) in African populations using a technique known as a genome-wide association (GWA) study. This is the first novel disease variant to be identified using this technique in Africans and demonstrates that such studies are viable in African populations, which have a high degree of genetic diversity.

9 Aug 2010

ASEBIO to host Biospain 2010

The Spanish Bioindustry Association (ASEBIO), in collaboration with the Navarre Society of Development (SODENA), and the government of Navarre, will host BioSpain 2010 the biennial international gathering of experts in the biotechnology sector, in Pamplona from September 29th to October 1st. BioSpain 2010 is honoured to welcome three lecturers of international prestige: Mr. Carlos Cordon-Cardo, Vice-Chair of Pathology & Professor, Columbia University; Mr. Larry Fritz, President & CEO, Covella Pharmaceuticals Inc. and Life Science Venture Partner, Westfield Capital Management Company LP; and Mr. Conny Bogentoft, CEO Karolinska Development AB.

8 Aug 2010

Agendia inaugurates new clinical genomics laboratory

Agendia, a world leader in molecular cancer diagnostics, today announced the inauguration of a new state-of-the-art clinical genomics laboratory in Irvine, CA. Previously, Agendia's offices and laboratory were located in Huntington Beach, CA. The new laboratory will further increase capacity to support Agendia's strong commercial expansion in the U.S. market, as well as the use of multiple Agendia tests in clinical research. MammaPrint, the company's lead product and the only FDA-cleared breast cancer recurrence test, is reimbursed by an increasing number of payers, covering some 100 million lives today.

6 Aug 2010

WaferGen launches SmartChip System for discovery, validation of biomarkers

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genomic analysis systems, today announced it has launched the breakthrough WaferGen SmartChip Real-Time PCR System, the next-generation Real-Time PCR system for discovery and validation of biomarkers, or gene expression patterns, on a single platform. The SmartChip System is designed to provide accurate, highly sensitive and high-throughput gene expression profiling capabilities to researchers, clinicians and pharmaceutical companies.

6 Aug 2010

Life Technologies, UCSD Moores Cancer Center to use SOLiD 4 technology to study CLL

Life Technologies Corporation and the University of California at San Diego Moores Cancer Center today announced a partnership to use SOLiD 4 genomic analysis technology in a research program to study chronic lymphocytic leukemia, a cancer of the white blood cells. The CLL research is made possible by funding from the National Institutes of Health and will enable scientists to survey the whole transcriptomes of 96 CLL tumor samples for potential biomarkers.

5 Aug 2010

Genomic sequence of living marine sponge reveals some basic information about cancer: Scientists

This week's publication of the complete genomic sequence of a living marine sponge reveals genes dating back hundreds of millions of years -- a result far exceeding the expectations of the scientific world.

5 Aug 2010

Alnylam second-quarter revenues increase to $26.6 million

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, today reported its consolidated financial results for the second quarter ended June 30, 2010, and company highlights.

5 Aug 2010

Sigma-Aldrich, NHLBI and BU collaborate in atherosclerotic cardiovascular disease research

Sigma-Aldrich® today announced it has entered into an agreement with the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, and Boston University (BU) to develop methods to measure several potential biomarkers of atherosclerotic cardiovascular disease (CVD) using plasma samples from the NHLBI's Framingham Heart Study (FHS), one of the most prestigious clinical studies in medicine. Funding for the project is provided by the NHLBI to Sigma-Aldrich under a research subaward agreement with BU.

5 Aug 2010

SORT1 pathway holds promise as new target for therapeutic intervention for LDL cholesterol reduction

The true power of genomic research lies in its ability to help scientists understand biological processes, particularly those that - when altered - can lead to disease. This power is demonstrated dramatically in a pair of papers published today in the journal Nature. In the first, a global team of researchers describes 95 different variations across the genome that contribute in different degrees to alterations in blood cholesterol and triglyceride levels in multiple human populations. In the second report, close examination of just one of these common variants not only reveals the involvement of an unexpected genetic pathway in lipid metabolism but also provides a blueprint for using genomic findings to unravel biological connections between lipid levels and coronary heart disease.

5 Aug 2010

Study links sea sponge genome sequence with first animals and cancer

The sponge, which was not recognized as an animal until the 19th century, is now the simplest and most ancient group of animals to have their genome sequenced. In a paper appearing in the August 5 issue of the journal Nature, a team of researchers led by Daniel Rokhsar of the University of California, Berkeley, and the Department of Energy's Joint Genome Institute (JGI), report the draft genome sequence of the sea sponge Amphimedon queenslandica and several insights the genome gives into the origins of both the first animals and cancer.

5 Aug 2010

QCMG selects SGI LiveArc storage solution for cancer genome sequence data processing

SGI, a global leader in HPC and data center solutions, today announced that the Queensland Centre for Medical Genomics at the University of Queensland has selected SGI LiveArc storage solution to increase its ability to store, manage and process human cancer genome sequence data. This project will contribute to mapping the genetic changes that lead to cancer, providing better understanding of such cancers and potentially helping to combat the disease.

4 Aug 2010

Caliper Life Sciences second-quarter GAAP revenue decreases 10% to $29.0 million

Caliper Life Sciences, Inc., today reported results for its second quarter ended June 30, 2010. Second quarter GAAP revenue decreased 10% to $29.0 million from $32.1 million in the same period in 2009 as a result of divestitures in 2010 and 2009. Revenue from on-going business increased 4% on a reported basis and 6% on an organic basis (which assumes constant currency).

3 Aug 2010

Mount Sinai joins MMRC to develop new treatments for multiple myeloma

The Multiple Myeloma Research Consortium (MMRC) and Mount Sinai School of Medicine today announced that Mount Sinai has become the newest Member Institution to join the MMRC to accelerate the development of new treatments for multiple myeloma.

3 Aug 2010

Researchers identify new genetic route to treat epilepsy

New research points to a genetic route to understanding and treating epilepsy. Timothy Jegla, an assistant professor of biology at Penn State University, has identified an ancient gene family that plays a role in regulating the excitability of nerves within the brain.

2 Aug 2010

Complete Genomics files registration statement on Form S-1 with SEC

Complete Genomics, Inc. announced today that it has filed a registration statement on Form S-1 with the U.S. Securities and Exchange Commission relating to the proposed initial public offering of shares of its common stock. The shares of common stock to be sold in this offering are proposed to be sold solely by Complete Genomics, Inc.

31 Jul 2010

AMP conducts survey on Genetic Test Registry

Today, the Association for Molecular Pathology (AMP) submitted written comments in response to the Request for Information made by the National Institutes of Health (NIH) for its Genetic Test Registry (GTR). AMP conducted a survey of its membership to formulate a comprehensive response to the RFI. "With the vast majority of respondents working in a clinical laboratory setting, AMP is able to inform the NIH on the general reaction to the GTR, including insight to the community's concerns and guidance to ensure the GTR is a valued resource," said Dr. Karen Mann, President of AMP.

31 Jul 2010

Researchers find new pathway that leads to brain cell death in neurodegenerative disorders

Although their genetic underpinnings differ, Alzheimer's disease, Parkinson's disease and Huntington's disease are all characterized by the untimely death of brain cells. What triggers cell death in the brain? According to a new study published by researchers at Sanford-Burnham Medical Research Institute in the July 30 issue of Molecular Cell, the answer in some cases is the untimely transfer of a gaseous molecule (known as nitric oxide, or NO) from one protein to another.

30 Jul 2010

Researchers identify genetic mutation for Uner Tan Syndrome

A team of researchers from leading universities in Turkey and the United States have reported that they have identified the genetic mutation responsible for the Uner Tan Syndrome (UTS) using advanced genetic capture and sequencing technologies from Roche. The combined genomic technologies enabled the team of scientists to identify the causative mutation of this debilitating disease after years of mystery.

30 Jul 2010

AVEO second-quarter total revenues increase to $15.6 million

AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics, today provided an update on recent research and development (R&D) and business accomplishments, and announced financial results for the quarter ended June 30, 2010.

29 Jul 2010

Scientists identify new targets to develop treatment for HD

Scientists at the Buck Institute for Age Research have discovered that a particular family of enzymes are involved in the breakdown of proteins that modify the production of toxic fragments that lead to the pathology of Huntington's disease. These enzymes, matrix metalloproteinases, provide new targets for drug therapies for the disease - targets that have already been shown to respond to cancer drugs currently in clinical development.

29 Jul 2010

Genomics News and Research

Further Reading

GWA Study helps scientists identify genetic variant that increases tuberculosis susceptibility in African populations

ASEBIO to host Biospain 2010

Agendia inaugurates new clinical genomics laboratory

WaferGen launches SmartChip System for discovery, validation of biomarkers

Life Technologies, UCSD Moores Cancer Center to use SOLiD 4 technology to study CLL

Genomic sequence of living marine sponge reveals some basic information about cancer: Scientists

Alnylam second-quarter revenues increase to $26.6 million

Sigma-Aldrich, NHLBI and BU collaborate in atherosclerotic cardiovascular disease research

SORT1 pathway holds promise as new target for therapeutic intervention for LDL cholesterol reduction

Study links sea sponge genome sequence with first animals and cancer

QCMG selects SGI LiveArc storage solution for cancer genome sequence data processing

Caliper Life Sciences second-quarter GAAP revenue decreases 10% to $29.0 million

Mount Sinai joins MMRC to develop new treatments for multiple myeloma

Researchers identify new genetic route to treat epilepsy

Complete Genomics files registration statement on Form S-1 with SEC

AMP conducts survey on Genetic Test Registry

Researchers find new pathway that leads to brain cell death in neurodegenerative disorders

Researchers identify genetic mutation for Uner Tan Syndrome

AVEO second-quarter total revenues increase to $15.6 million

Scientists identify new targets to develop treatment for HD

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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