Lab on a Chip News and Research

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Advances in the field of nanotechnology have led to the development of miniaturized devices called lab-on-a-chip (LOC). Lithography, in particular, has helped create nanoscale impressions on the surface of metals and semiconductors.

New cell analysis platform developed - commercial partners sought

Sandia National Laboratories is seeking commercial partners to license or contribute to the continued development of a new lab-on-a-chip platform for high-throughput manipulation and interrogation of individual cells, one that enables quantitative analysis of cellular behaviors with unprecedented speed, resolution, sensitivity, and multiplexing.

1 Dec 2008

$2 egg-beater - low-cost centrifuge replacement - could save lives in developing countries

Plastic tubing taped to a handheld egg-beater could save lives in developing countries, the Royal Society of Chemistry's journal Lab on a Chip reports.

16 Oct 2008

Scientists develop ultra-sensitive optical protein sensor, a first for a salivary diagnostic test

For people who dislike needles, medical tests that require a drop of saliva instead of a vial of blood will one day make a trip to a doctor or dentist much easier. But as scientists now construct the first of these saliva tests for early signs of cancer and other diseases, they continue to push the technological envelope in interesting ways.

3 Aug 2008

A micro-sized sewing machine for DNA

Japanese scientists have made a micro-sized sewing machine to sew long threads of DNA into shape. The work published in the Royal Society of Chemistry journal Lab on a Chip demonstrates a unique way to manipulate delicate DNA chains without breaking them.

10 Jul 2008

Disease-detecting lab-on-a-chip

Detecting food-borne diseases such as campylobacter and salmonella long before they enter the food chain would help ensure that the dinner on your table is safe to eat.

1 Jul 2008

Chip-based device measures drug resistance in tumor cells

Multiple drug resistance is a major cause of anticancer therapy failure. Most drug-resistance cancer cells develop this unfortunate characteristic due to a drug-pumping protein known as P-glycoprotein.

20 May 2008

A biosensing nanodevice to revolutionize health screenings

One day soon a biosensing nanodevice developed by Arizona State University researcher Wayne Frasch may eliminate long lines at airport security checkpoints and revolutionize health screenings for diseases like anthrax, cancer and antibiotic resistant Staphylococcus aureus (MRSA).

26 Mar 2008

Lab on a chip mimics chemical complexities of the brain

Johns Hopkins researchers from the Whiting School of Engineering and the School of Medicine have devised a micro-scale tool - a lab on a chip - designed to mimic the chemical complexities of the brain.

13 Feb 2008

Light beams used as tweezers to manipulate cells

In a feat that seems like something out of a microscopic version of Star Trek, MIT researchers have found a way to use a "tractor beam" of light to pick up, hold, and move around individual cells and other objects on the surface of a microchip.

31 Oct 2007

New magnetic separation 'traveling wave magnetophoresis' might detect multiple pathogens at once

A magnetic separation technique developed by researchers at Duke University's Pratt School of Engineering and Purdue University makes it relatively simple to sort through beads hundreds of times smaller than the period at the end of this sentence.

29 Oct 2007

New imaging technique ensures rapid profiling of autoantibodies in rheumatoid arthritis

Using a new imaging technique, a fast and accurate profile of autoantibodies present in the blood serum of rheumatic patients can be made.

25 Oct 2007

New test detects the presence of biogenic amines

Researchers in California are reporting development of a fast, inexpensive test suitable for home use that could help millions of people avoid those 'out of the blue' headaches that may follow consumption of certain red wines, cheese, chocolate, and other aged or fermented foods.

2 Oct 2007

When biological molecules kiss, a new kind of biosensor can tell

A new and deceptively simple technique has been developed by chemists at Vanderbilt University that can measure the interactions between free-floating, unlabeled biological molecules including proteins, sugars, antibodies, DNA and RNA.

21 Sep 2007

Microfluidic chambers advance the science of growing neurons

Researchers at the University of Illinois have developed a method for culturing mammalian neurons in chambers not much larger than the neurons themselves.

30 Aug 2007

Cell-based sensor for analysis of EGFR biomarker expression in oral cancer

Using a microfluidic device designed to capture and enrich cells from biological samples, a research team at The University of Texas at Austin has developed a test that can detect an important early marker for oral squamous cell carcinoma, which accounts for more than 90 percent of oral cancers. Oral cancer is the sixth most common cancer worldwide and is difficult to detect early enough to treat successfully.

22 Aug 2007