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Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggests that an unusual experimental drug can reduce breast-cancer aggressiveness, reverse resistance to the drug fulvestrant and perhaps improve the effectiveness of other breast-cancer drugs.

23 Apr 2013

GeneCapture developing new device with one-hour pathogen testing capabilities

A company hatched as a partnership between The University of Alabama in Huntsville and chemical engineering professor Dr. Krishnan Chittur is in the design phase for a device that can provide physicians one-hour pathogen testing capabilities.

23 Apr 2013

Researchers urge doctors to consider Lyme disease as cause when presented with skin lesions

When a person contracts Lyme disease, quick diagnosis and treatment are essential to avoiding long term complications. But the diagnostic process may be delayed if a physician does not recognize a skin rash caused by Lyme disease because it does not have the bull's-eye appearance that is best known to physicians and the public.

23 Apr 2013

TSRI scientists find way to directly turn bone marrow stem cells into brain cells

In a serendipitous discovery, scientists at The Scripps Research Institute have found a way to turn bone marrow stem cells directly into brain cells.

23 Apr 2013

$Johns Hopkins researchers find that diagnostic errors accounted for largest fraction of claims$

Johns Hopkins researchers find that diagnostic errors accounted for largest fraction of claims

In reviewing 25 years of U.S. malpractice claim payouts, Johns Hopkins researchers found that diagnostic errors — not surgical mistakes or medication overdoses — accounted for the largest fraction of claims, the most severe patient harm, and the highest total of penalty payouts.

23 Apr 2013

DNAzymes, gold nanoparticles and disease detection: an interview with Dr Chan and Kyryl Zagorovsky, University of Toronto

Gold nanoparticles are tiny spherical particles made out of gold atoms with sizes on nanometre scale. This is around 1,000 times smaller than the thickness of human hair.

23 Apr 2013

BioInvent starts BI-505 phase II study in patients with smoldering multiple myeloma

BioInvent International announced today that the first patient has been treated in a phase II study of the drug candidate BI-505, developed for the treatment of multiple myeloma.

23 Apr 2013

University of Utah researchers develop novel technique to identify RNA cytosine methyltransferases

Researchers from Huntsman Cancer Institute at the University of Utah have developed a novel and powerful technique to identify the targets for a group of enzymes called RNA cytosine methyltransferases in human RNA.

23 Apr 2013

New study of Antarctic clams reveals age matters when it comes to adapting to effects of climate change

A new study of Antarctic clams reveals that age matters when it comes to adapting to the effects of climate change. The research provides new insight and understanding of the likely impact of predicted environmental change on future ocean biodiversity.

22 Apr 2013

Discovery reverses the prevailing model of how dividing cells monitor equal distribution of chromosomes

Ludwig researchers Arshad Desai and Christopher Campbell, a post-doctoral fellow in his laboratory, were conducting an experiment to parse the molecular details of cell division about three years ago, when they engineered a mutant yeast cell as a control that, in theory, had no chance of surviving. Apparently unaware of this, the mutant thrived.

22 Apr 2013

New licensing agreement to promote discovery in health IT and improve economic Growth

The Regenstrief Institute Inc., an international leader in electronic medical records and health information exchange research, development and operations, is licensing its Indiana Network for Patient Care and DOCS4DOCS clinical results delivery software to a subsidiary of the Indiana Health Information Exchange. This licensing agreement represents the single most significant transfer of discovery out of an academic medical informatics research setting to a commercial enterprise in the history of Indiana's health information technology sector and the national evolution of health information exchange.

22 Apr 2013

Researchers win Jacob Heskel Gabbay Award in Biotechnology and Medicine

Karl Deisseroth of Stanford University, Gero Miesenb-ck of the University of Oxford and Edward S. Boyden of the Massachusetts Institute of Technology have been awarded Brandeis University's 16th Annual Jacob Heskel Gabbay Award in Biotechnology and Medicine.

22 Apr 2013

Photoacoustic imaging helps preserve healthy nodes in patients with metastasized cancer

If a tumour has spread through the lymph nodes, the decision is often taken to exercise caution and remove extra tissue, to prevent it from spreading further. This often involves the removal of healthy lymph nodes.

22 Apr 2013

3D image of cell signaling molecules indicates a trippable power switch

A three-dimensional image of one of the proteins that serves as an on-off switch as it binds to receptors on the surface of a cell suggests there may be a sort of main power switch that could be tripped. These surface receptors are responsible for helping cells discern light, set the heart racing, or detect pain.

22 Apr 2013

Researchers use contrast-computed tomography for anatomical reconstruction of human heart

On April 18th JoVE (Journal of Visualized Experiments) will publish a new video article by Dr. Paul A Iaizzo demonstrating the anatomical reconstruction of an active human heart. The research uses contrast-computed tomography (CT) to allow in-depth 3-D computer modeling of hearts that can be used for prolonged archiving.

22 Apr 2013

Edible malarial vaccine may work against other viral and bacterial infections

Can scientists rid malaria from the Third World by simply feeding algae genetically engineered with a vaccine? That's the question biologists at UC San Diego sought to answer after they demonstrated last May that algae can be engineered to produce a vaccine that blocks malaria transmission.

22 Apr 2013

Sleep related breathing disorders associated with cognitive and behavioral impairment in children

People lobbying for gun control may want to consider another culprit in the post-Newtown search for the answer to our unfathomable questions.

22 Apr 2013

Study identifies potential drug targets that interfere with cancer metabolism

A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer.

22 Apr 2013

Research reveals how three-dimensional, volumetric, space is perceived in mammalian brains

Animals navigate and orient themselves to survive - to find food and shelter or avoid predators, for example. Research conducted by Dr. Nachum Ulanovsky and research student Michael Yartsev of the Weizmann Institute's Neurobiology Department, published today in Science, reveals for the first time how three-dimensional, volumetric, space is perceived in mammalian brains.

22 Apr 2013

Researchers decipher the underlying mechanism of antiviral drug

A long-forgotten candidate for antiviral therapy is undergoing a renaissance: Since the 1970s, the small molecule CMA has been considered a potent agent against viral infections, yet it was never approved for clinical use.

22 Apr 2013

Laboratory News and Research

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

GeneCapture developing new device with one-hour pathogen testing capabilities

Researchers urge doctors to consider Lyme disease as cause when presented with skin lesions

TSRI scientists find way to directly turn bone marrow stem cells into brain cells

Johns Hopkins researchers find that diagnostic errors accounted for largest fraction of claims

DNAzymes, gold nanoparticles and disease detection: an interview with Dr Chan and Kyryl Zagorovsky, University of Toronto

BioInvent starts BI-505 phase II study in patients with smoldering multiple myeloma

University of Utah researchers develop novel technique to identify RNA cytosine methyltransferases

New study of Antarctic clams reveals age matters when it comes to adapting to effects of climate change

Discovery reverses the prevailing model of how dividing cells monitor equal distribution of chromosomes

New licensing agreement to promote discovery in health IT and improve economic Growth

Researchers win Jacob Heskel Gabbay Award in Biotechnology and Medicine

Photoacoustic imaging helps preserve healthy nodes in patients with metastasized cancer

3D image of cell signaling molecules indicates a trippable power switch

Researchers use contrast-computed tomography for anatomical reconstruction of human heart

Edible malarial vaccine may work against other viral and bacterial infections

Sleep related breathing disorders associated with cognitive and behavioral impairment in children

Study identifies potential drug targets that interfere with cancer metabolism

Research reveals how three-dimensional, volumetric, space is perceived in mammalian brains

Researchers decipher the underlying mechanism of antiviral drug

Lab Diagnostics and Automation - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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