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DNAzymes and gold nanoparticles used to detect infectious diseases

Infectious diseases such as malaria and syphilis can be diagnosed rapidly and reliably in the field by using a simple test developed by Canadian scientists. The test is based on the use of DNAzymes and gold nanoparticles. As the researchers report in the journal Angewandte Chemie, their test allows for the sensitive detection of bacteria, viruses, and parasites.

12 Feb 2013

Metastatic renal cell carcinoma (mRCC) therapy: an interview with Charles A. Nicolette, Ph.D., CSO of Argos Therapeutics

Metastatic renal cell carcinoma is a devastating disease. There are roughly 20-25,000 new cases per year in the United States and it is increasing for some reason.

12 Feb 2013

Berkeley Lab researchers resolve EGFR activation mystery

Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have provided important new details into the activation of the epidermal growth factor receptor (EGFR), a cell surface protein that has been strongly linked to a large number of cancers and is a major target of cancer therapies.

12 Feb 2013

Cholera cases confirmed in northern Mozambique after heavy rains, flooding

"In the last 10 days, 22 cases of the waterborne disease cholera have been confirmed by laboratory testing in three areas in and around the northern Mozambique town of Pemba, in Cabo Delgado Province," IRIN reports.

12 Feb 2013

Developing tiny probes for research and brain-related medical applications

Developing tiny probes for research and brain-related medical applications - that is the goal of the project NeuroSeeker, launched in February 2013 with a kick-off event in Leuven, Belgium.

12 Feb 2013

Florida Hospital, Sanford-Burnham and Takeda renew research agreement

Sanford-Burnham Medical Research Institute (Sanford-Burnham) and Florida Hospital announced today that they have renewed a research agreement with Takeda Pharmaceutical Company Limited (Takeda) to extend their collaboration to discover and evaluate new therapeutic approaches to obesity. The collaboration uses a research and drug-development model that creates an early feedback loop in the discovery pipeline.

12 Feb 2013

Two different mechanisms trigger early-onset prostate cancers

While prostate cancer is the most common cancer in elderly Western men it also, but more rarely, strikes patients aged between 35 and 50. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with several other research teams in Germany, have discovered that such early-onset prostate cancers are triggered by a different mechanism from that which causes the disease at a later age.

12 Feb 2013

RNF20 protein required for MLL-rearranged leukemia amplification

Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible for this cancer in order to generate potential new therapeutics.

12 Feb 2013

AB SCIEX releases new testing method for laboratories to detect DCD in dairy products

AB SCIEX today announced the release of a new testing method for laboratories to screen for and quantify dicyandiamide ‒ known as DCD ‒ in dairy products and other protein-rich foods.

12 Feb 2013

Short but frequent exercise best for beating weight gain

Results from a small exploratory study suggest that short bouts of intermittent exercise may stimulate fat metabolism more effectively than longer continuous exercise sessions.

11 Feb 2013

Researchers discover miR-27b that regulates lipid levels in the blood

Researchers have identified a microRNA liver gene, miR-27b, which regulates lipid (cholesterol or fat) levels in the blood. This regulator gene controls multiple genes involved in dyslipidemia-abnormal blood cholesterol levels that can contribute to heart disease.

11 Feb 2013

Combined genomic and proteomic plasma analysis can identify molecular disease mechanisms

For the first time, scientists have combined genomic and proteomic analysis of blood plasma to enhance identification of genetically regulated protein traits. This could be applied to any large association study of civilization diseases where blood plasma has been collected, vastly improving a clinician's ability to identify disease susceptibility in individuals and populations.

11 Feb 2013

MicroRNA can be used to define four subtypes of triple-negative breast cancer

A new, large-scale study of triple-negative breast cancer shows that small molecules called microRNA can be used to define four subtypes of this aggressive malignancy.

11 Feb 2013

Scientists discover natural trigger that enables stem cell development

A natural trigger that enables stem cells to become any cell-type in the body has been discovered by scientists.

10 Feb 2013

Virginia Tech researchers reveal how 'bad' gut bacteria may help control diabetes

A stomach bacterium believed to cause health problems such as gastritis, ulcers, and gastric cancer may play a dual role by balancing the stomach's ecosystem and controlling body weight and glucose tolerance, according to immunologists at the Virginia Bioinformatics Institute of Virginia Tech.

10 Feb 2013

Tat-beclin 1 shows promise against infections, neurodegenerative disorders and cancer

UT Southwestern Medical Center scientists have synthesized a peptide that shows potential for pharmaceutical development into agents for treating infections, neurodegenerative disorders, and cancer through an ability to induce a cell-recycling process called autophagy.

10 Feb 2013

Global response to possible H5N1 flu outbreak could affect epidemic's course

"It's been a rough flu season this winter in the United States and Europe, but it could be worse. A lot worse," science writer Carl Zimmer states in National Geographic's "Phenomena: The Loom" blog.

10 Feb 2013

KFH/HP 2012 combined total operating revenue increases to $50.6 billion

Kaiser Foundation Hospitals, Kaiser Foundation Health Plan, Inc., and their subsidiaries (KFH/HP) reported today that combined total operating revenue for 2012 was $50.6 billion, compared to $47.9 billion in 2011.

10 Feb 2013

Northwestern Medicine to open new Outpatient Center in Glenview, Illinois

Northwestern Medicine today announced that on March 1 it will open a new Outpatient Center at 2701 Patriot Boulevard in Glenview, Illinois. At this new center, 20-30 physicians will offer patients a wide range of primary care and specialty clinical services.

10 Feb 2013

Researchers develop special version of iDichotic for patients with schizophrenia

Two years ago, researcher Josef Bless was listening to music on his phone when he suddenly had an idea. "I noticed that the sounds of the different instruments were distributed differently between the ears, and it struck me that this was very similar to the tests we routinely use in our laboratory to measure brain function. In dichotic listening, each ear is presented with a different syllable at the same time and the listener has to say which syllable seems clearest. The test indicates which side of the brain is most active during language processing," Bless explains.

10 Feb 2013