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New targeted enzyme replacement therapy can treat X-linked myotubular myopathy

A collaborative research team including a Medical College of Wisconsin (MCW) pediatric neuropathologist successfully mitigated some of the effects of a muscular disease by using a new targeted enzyme replacement therapy strategy from 4s3 Bioscience.

23 Jan 2013

Exposure of human f-tal testicles to bisphenol A reduces testosterone production

Bisphenol A (BPA) is a chemical compound that is included in the composition of plastics and resins. It is used, for example, in the manufacture of food containers such as bottles and babies' feeding bottles. It is also found in the protective films used inside food and drink cans and on till receipts where it used as a discloser. Significant levels of BPA have also been found in human blood, urine, amniotic fluid and placentas.

23 Jan 2013

Novel way to engineer specialized immune cells targeted by the AIDS virus

Researchers at the Stanford University School of Medicine have found a novel way to engineer key cells of the immune system so they remain resistant to infection with HIV, the virus that causes AIDS.

23 Jan 2013

Research on dystrophin gene sequence could lead to treatments for Duchenne muscular dystrophy

Muscular dystrophy is caused by the largest human gene, a complex chemical leviathan that has confounded scientists for decades. Research conducted at the University of Missouri and described this month in the Proceedings of the National Academy of Sciences has identified significant sections of the gene that could provide hope to young patients and families.

23 Jan 2013

SV Bio, Mayo Clinic partner on whole genome diagnostics and interpretation

Mayo Clinic and Silicon Valley Biosystems (SV Bio) today announced a strategic collaboration for whole genome diagnostics and interpretation at the Mayo Clinic Center for Individualized Medicine and Mayo Medical Laboratories.

23 Jan 2013

SLU team discovers molecular pathway that contributes to triple-negative breast cancer

In research published in the Jan. 17 issue of The Journal of Cell Biology, a team led by Susana Gonzalo, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, has discovered a molecular pathway that contributes to triple-negative breast cancer, an often deadly and treatment resistant form of cancer that tends to strike younger women.

23 Jan 2013

ParseCNV software can detect disease-causing copy number variations

A novel software tool, developed at The Children's Hospital of Philadelphia, streamlines the detection of disease-causing genetic changes through more sensitive detection methods and by automatically correcting for variations that reduce the accuracy of results in conventional software.

22 Jan 2013

PathCentral announces roll-out of new pathology network

PathCentral, a technology-enabled company dedicated to the success of the international pathology community, and China-based Kindstar Globalgene Technology, Inc., today announced the roll-out of the PathCentral Pathology Network, an online professional pathology network that will enable Kindstar to access US pathologists and facilitate pathology consultations for more than 3,300 hospitals throughout China.

22 Jan 2013

Suppression of immune system function can occur in influenza patients

Investigators from 15 children's medical centers, including Nationwide Children's Hospital, observed and evaluated critically ill children with influenza to evaluate the relationships between levels of systemic inflammation, immune function and likelihood to die from the illness. The study appears in the January issue of Critical Care Medicine.

22 Jan 2013

Waters and Fera launch new international food safety training facility

A major new international food safety training facility, aimed at improving compliance with EU food import standards, is being launched today by The Food and Environment Research Agency (Fera) and analytical equipment manufacturer Waters®.

22 Jan 2013

INPC provides early warning of influenza outbreaks and other communicable diseases

The Centers for Disease Control has reported that influenza activity is high across most of the United States. The Indiana Network for Patient Care's ability to track data from physician offices and medical facilities across Indiana provides public health officials in the Hoosier state with early warning of outbreaks of influenza and other communicable diseases in Indiana.

22 Jan 2013

Studies suggest a new approach to treating HIV

A team of researchers based at Johns Hopkins has decoded a system that makes certain types of immune cells impervious to HIV infection.

22 Jan 2013

Neuronal reprogramming may help treat neurodegenerative diseases

A new finding by Harvard stem cell biologists turns one of the basics of neurobiology on its head - demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.

22 Jan 2013

Study finds high ADHD diagnosis rates among non-Hispanic children between 2001 and 2010

The rate of children diagnosed with Attention Deficit Hyperactivity Disorder rose dramatically between 2001 and 2010 with non-Hispanic white children having the highest diagnosis rates, according to a Kaiser Permanente study published in the journal JAMA Pediatrics (formerly Archives of Pediatrics and Adolescent Medicine).

22 Jan 2013

New imaging method for study of insulin-producing cells in diabetes

A new imaging method for the study of insulin-producing cells in diabetes among other uses is now being presented by a group of researchers at Umeå University in Sweden in the form of a video in the biomedical video journal, The Journal of Visualized Experiments.

21 Jan 2013

Itch-specific nerve cells: an interview with Associate Professor Xinzhong Dong

Itch was actually defined by a German physician more than 350 years ago. His name was Samuel Hafenreffer. He defined itch as an unpleasant sensation that makes people want to scratch. You probably think this is a very simple definition but itch is really a very complex sensory modality.

21 Jan 2013

Scientists identify new mechanism that turns CD4 helper T lymphocytes into killer cells

A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against viruses, cancerous tumors and other damaged or infected cells.

21 Jan 2013

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.

21 Jan 2013

Intestinal bacteria can produce biochemicals and hormones that stop development of diabetes

All humans have enormous numbers of bacteria and other micro-organisms (10 to 14) in the lower intestine. In fact our bodies contain about ten times more bacteria than our own cells and these tiny passengers are extremely important for our health. They help us digest our food and provide us with energy and vitamins.

19 Jan 2013

Possible connection between mitochondrial CYP2D6 and Parkinson's

With a new insight into a model of Parkinson's disease, researchers from the University of Pennsylvania School of Veterinary Medicine have identified a novel target for mitigating some of the disease's toll on the brain.

19 Jan 2013

Laboratory News and Research

New targeted enzyme replacement therapy can treat X-linked myotubular myopathy

Exposure of human f-tal testicles to bisphenol A reduces testosterone production

Novel way to engineer specialized immune cells targeted by the AIDS virus

Research on dystrophin gene sequence could lead to treatments for Duchenne muscular dystrophy

SV Bio, Mayo Clinic partner on whole genome diagnostics and interpretation

SLU team discovers molecular pathway that contributes to triple-negative breast cancer

ParseCNV software can detect disease-causing copy number variations

PathCentral announces roll-out of new pathology network

Suppression of immune system function can occur in influenza patients

Waters and Fera launch new international food safety training facility

INPC provides early warning of influenza outbreaks and other communicable diseases

Studies suggest a new approach to treating HIV

Neuronal reprogramming may help treat neurodegenerative diseases

Study finds high ADHD diagnosis rates among non-Hispanic children between 2001 and 2010

New imaging method for study of insulin-producing cells in diabetes

Itch-specific nerve cells: an interview with Associate Professor Xinzhong Dong

Scientists identify new mechanism that turns CD4 helper T lymphocytes into killer cells

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

Intestinal bacteria can produce biochemicals and hormones that stop development of diabetes

Possible connection between mitochondrial CYP2D6 and Parkinson's

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