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Transplanting spermatogonial stem cells could restore fertility in male cancer patients

Radiation and chemotherapy can pack a powerful punch against all kinds of cancers. Those who survive, however, are often left with bad news: Their treatments have rendered them infertile.

11 Dec 2012

FAC PET identifies liposarcoma tumors that are sensitive to chemotherapy

Liposarcoma, the most common type of sarcoma, is an often lethal form of cancer that develops in fat cells. It is particularly deadly, in part, because the tumors are not consistently visible with positron emission tomography (PET) scans that use a common probe called FDG and because they frequently do not respond to chemotherapy.

11 Dec 2012

Oxytocin administration to fathers increases parental engagement with their infants

A large body of research has focused on the ability of oxytocin to facilitate social bonding in both marital and parenting relationships in human females. A new laboratory study, led by Dr. Ruth Feldman from Bar-Ilan University in Israel and published in the current issue of Biological Psychiatry, has found that oxytocin administration to fathers increases their parental engagement, with parallel effects observed in their infants.

11 Dec 2012

FDA expands approved use of Janssen Biotech’s Zytiga to treat men with mCRPC

The U.S. Food and Drug Administration today expanded the approved use of Zytiga (abiraterone acetate) to treat men with late-stage (metastatic) castration-resistant prostate cancer prior to receiving chemotherapy.

10 Dec 2012

Childhood obesity: an interview with Professor Clodagh O’Gorman

Childhood obesity is harder to define than adult obesity. This is because any definition of obesity relies on measurements of both height and weight, and the calculation of body mass index (BMI) based on these measurements.

10 Dec 2012

Potential way to attack common stomach bacteria that cause ulcers

Experiments at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have revealed a potential new way to attack common stomach bacteria that cause ulcers and significantly increase the odds of developing stomach cancer.

10 Dec 2012

New assay test shows positive results for patients with recurrent or metastatic breast cancer

When breast cancer advances, the patient doesn't have the luxury of time. Finding the right type of chemotherapy as quickly as possible is a critical factor for the patient's success and, until now, predicting the patient's sensitivity to chemotherapy has often been a shot in the dark.

10 Dec 2012

New hope for leukemia patients

Nine of twelve leukemia patients who received infusions of their own T cells after the cells had been genetically engineered to attack the patients' tumors responded to the therapy, which was pioneered by scientists in the Perelman School of Medicine at the University of Pennsylvania

10 Dec 2012

Vorinostat reduces risk of graft-vs.-host disease from bone marrow transplant treatments

A new class of drugs reduced the risk of patients contracting a serious and often deadly side effect of lifesaving bone marrow transplant treatments, according to a study from researchers at the University of Michigan Comprehensive Cancer Center.

10 Dec 2012

Sinai Hospital of Baltimore announces opening of new geriatric surgery center

Sinai Hospital of Baltimore, a LifeBridge Health center, is proud to announce the opening of the Sinai Center for Geriatric Surgery, the nation's first surgical center dedicated exclusively to providing specialized surgical and pre and postoperative care for elderly patients.

10 Dec 2012

Most triple-negative breast cancer patients have multiple genetic mutations after chemo treatment

Most triple-negative breast cancer patients who were treated with chemotherapy to shrink the tumor prior to surgery still had multiple genetic mutations in their tumor cells, according to a study by Vanderbilt-Ingram Cancer Center (VICC) investigators.

10 Dec 2012

C5aRA treatment could be effective against periodontitis

Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In its most severe form, which affects 8.5 percent of U.S. adults, periodontitis can impact systemic health.

9 Dec 2012

New public-private partnership will allow Brazil to produce patented ARV for national treatment program

For the first time, Brazil in 2013 will enter into a new type of public-private partnership that allows the nation to produce a generic version of the antiretroviral (ARV) drug atazanavir sulphate, which will be under patent through its producer Bristol-Myers Squibb until 2017, Inter Press Service reports.

8 Dec 2012

Roundup: Ga. 'provider fee' defeat could mean $430M less for Medicaid; Minn. health programs in line for $37M cut over fiscal cliff; Calif. stem cell board criticized

Just weeks before the 2013 General Assembly convenes, the state's provider fee, called a "bed tax" by some, remains a high-profile wild card -- one that could deal Georgia's hospital industry a crippling blow. If the fee is not renewed -- and anti-tax forces will oppose it -- the Medicaid system may lose $430 million-plus that the assessment now generates. That loss would swell the state's Medicaid financial shortfall, which is already about $400 million (Miller, 12/6).

7 Dec 2012

Novel sensor measures individual particles in blood samples

Norwegian researchers have developed the world's first sensor capable of measuring individual particles in a blood sample. This new innovation could cause a sensation in the medical world.

7 Dec 2012

Drug offers alternative treatment strategy for insomnia

Orexin receptor antagonism may offer a novel treatment approach to insomnia, clinical findings suggest.

7 Dec 2012

CRP40 may have pathogenic role in schizophrenia

Gene expression of catecholamine-regulated protein 40 is dysregulated in people with schizophrenia, study findings show.

7 Dec 2012

Study demonstrates how parasites enter the brain to influence its host

Toxoplasma is a common 'cat parasite', and has previously been in the spotlight owing to its observed effect on risk-taking and other human behaviours. To some extent, it has also been associated with mental illness. A study led by researchers from Karolinska Institutet in Sweden now demonstrates for the first time how the parasite enters the brain to influence its host.

7 Dec 2012

Study finds previously unrecognized way that degradation can occur in silicone-urethane plastics

Scientists have discovered a previously unrecognized way that degradation can occur in silicone-urethane plastics that are often considered for use in medical devices. Their study, published in ACS' journal Macromolecules, could have implications for device manufacturers considering use of these plastics in the design of some implantable devices, including cardiac defibrillation leads.

7 Dec 2012

JAACAP editorial addresses 'translation gap' in autism research

An editorial published in the November 2012 issue of the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP) discusses the challenge of translating scientific research in autism into clinical practice, and presents a series of studies published over several months that address this 'translation gap'.

7 Dec 2012

Laboratory News and Research

Transplanting spermatogonial stem cells could restore fertility in male cancer patients

FAC PET identifies liposarcoma tumors that are sensitive to chemotherapy

Oxytocin administration to fathers increases parental engagement with their infants

FDA expands approved use of Janssen Biotech’s Zytiga to treat men with mCRPC

Childhood obesity: an interview with Professor Clodagh O’Gorman

Potential way to attack common stomach bacteria that cause ulcers

New assay test shows positive results for patients with recurrent or metastatic breast cancer

New hope for leukemia patients

Vorinostat reduces risk of graft-vs.-host disease from bone marrow transplant treatments

Sinai Hospital of Baltimore announces opening of new geriatric surgery center

Most triple-negative breast cancer patients have multiple genetic mutations after chemo treatment

C5aRA treatment could be effective against periodontitis

New public-private partnership will allow Brazil to produce patented ARV for national treatment program

Roundup: Ga. 'provider fee' defeat could mean $430M less for Medicaid; Minn. health programs in line for $37M cut over fiscal cliff; Calif. stem cell board criticized

Novel sensor measures individual particles in blood samples

Drug offers alternative treatment strategy for insomnia

CRP40 may have pathogenic role in schizophrenia

Study demonstrates how parasites enter the brain to influence its host

Study finds previously unrecognized way that degradation can occur in silicone-urethane plastics

JAACAP editorial addresses 'translation gap' in autism research

Lab Diagnostics and Automation - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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