Laboratory News and Research

RSS

Inspiration receives FDA clinical hold order for IB1001 phase III studies on hemophilia B

Ipsen announced today that its partner Inspiration Biopharmaceuticals Inc. (Inspiration) was notified by the Food and Drug Administration (FDA) that both clinical trials evaluating the safety and efficacy of IB1001, an investigational intravenous recombinant factor IX (rFIX) therapy for the treatment and prevention of bleeding episodes in people with hemophilia B, were placed on clinical hold.

10 Jul 2012

UTSMC could play key role in operating a proton therapy center for North Texas

UT Southwestern Medical Center, seeking to broaden an already robust array of radiation oncology treatments it offers to patients, potentially could play a key role in operating a state-of-the-art proton therapy center for North Texas being planned and funded by San Diego-based Advanced Particle Therapy (APT).

10 Jul 2012

Scientists can identify distinctive patterns of chemicals in the urine of children with autism

On her laptop computer one recent afternoon, University at Buffalo researcher Charmion Cruickshank calls up a mass spectrometry readout showing the breakdown of chemicals in the urine of a child with autism.

10 Jul 2012

Special surface coating for stents to keep them in place

If a person's windpipe is constricted, an operation in which the surgeon inserts a stent to enlarge the trachea is often the only way to relieve their respiratory distress. But this grid-like implant can slip out of position, closing off the windpipe altogether. Researchers are working on a special surface coating for the stents to keep them in place.

9 Jul 2012

IL announces worldwide launch of ACL TOP 300 CTS Hemostasis Testing System

Instrumentation Laboratory (IL), today, announced the worldwide commercial launch of the ACL TOP 300 CTS Hemostasis Testing System, as the newest member of the ACL TOP Family. Ideally suited for processing 50-100 patient samples per day, the ACL TOP 300 CTS offers full Testing Process Automation for low-to-medium-volume, routine or specialty Hemostasis laboratories or as an adjunct to other installed ACL TOP systems.

9 Jul 2012

BioView, ScreenCell enter collaboration agreement for imaging of CTC

BioView Ltd. and ScreenCell, a privately-held company, today jointly announced the signing of a commercial collaboration agreement for Bioview's Automated Cell Imaging Systems for imaging of CTC's isolated with ScreenCell's Cyto Kit.

9 Jul 2012

Luminex to acquire molecular diagnostics company, GenturaDx

Luminex Corporation today announced a definitive agreement to acquire privately-held, GenturaDx, a molecular diagnostics company focused on making nucleic acid testing both affordable and practical for any laboratory. GenturaDx is in late stage development of a fully integrated, highly automated, real-time PCR system that employs a single-use cassette for true sample-to-answer workflow.

From Luminex 9 Jul 2012

Researchers use metal complexes to modify peptide hormones

Researchers at the RUB and from Berkeley have used metal complexes to modify peptide hormones. In the Journal of the American Chemical Society, they report for the first time on the three-dimensional structure of the resulting metal-peptide compounds.

9 Jul 2012

Next generation predictive 3D cell toxicity assays to be developed by Medicyte GmbH and Reinnervate Ltd

Two market leading companies in the field of cell based assays and predictive toxicology today announced a new product collaboration. Medicyte (inventors of the upcyte® technology) and Reinnervate (market leaders in the growing field of 3D cell culture) said they will work together to combine their upcyte® and Alvetex®Scaffold technologies to bring next generation cell bases assays to the biopharma and academic research markets.

9 Jul 2012

Sectioning of bone as a specialist histology specimen

The significance of histological examination in the classification and diagnosis of clinical conditions is reliant on the expertise of the histology laboratory in managing the wide spectrum of specimen types submitted for analysis.

From Thermo Fisher Scientific Inc. 9 Jul 2012

DNA from CF patients with and without chronic infections points to unsuspected mutation

Comparing the DNA from patients at the best and worst extremes of a health condition can reveal genes for resistance and susceptibly. This approach discovered rare variations in the DCTN4 gene among cystic fibrosis patients most prone to early, chronic airway infections.

9 Jul 2012

More than 570 pioneering dentists assembled at MDL USA's World Dental Forum

Modern Dental Laboratory USA (MDL USA) assembled a group of 570 pioneering dentists from all over the world to come together at their second-annual World Dental Forum in Hong Kong and Shenzhen, China from May 31 to June 3, 2012.

8 Jul 2012

Mouse model demonstrates role of AEG-1 in hepatocellular carcinoma

Researchers have created the first mouse model demonstrating the role of a cancer promoting gene, Astrocyte elevated gene-1 (AEG-1), in hepatocellular carcinoma, or liver cancer. The mouse model represents a critical step in understanding the molecular mechanisms of liver cancer progression and could lead to novel therapies for the disease.

8 Jul 2012

Effect of spaceflight on C. elegans could help it to live longer

The effect of spaceflight on a microscopic worm - Caenorhabditis elegans (C. elegans) - could help it to live longer.

8 Jul 2012

NIH awards Clinical and Translational Science Award to three Texas Medical Center institutions

In 2006, three Texas Medical Center institutions were among the first in the nation to receive a Clinical and Translational Science Award (CTSA) from the National Institutes of Health (NIH) to accelerate the translation of laboratory discoveries into patient treatments. That grant has been renewed for another 5 years.

7 Jul 2012

Safe optimal concentration of propolis against radiation-induced damage

Researchers determined the amount of propolis offering maximum protection against ionised radiations without being toxic to blood cells.

7 Jul 2012

New optical microscope identifies rare breast cancer cells

The ability to distinguish and isolate rare cells from among a large population of assorted cells has become increasingly important for the early detection of disease and for monitoring disease treatments.

7 Jul 2012

FDA approves at-home HIV test, available in Oct.

The FDA has approved an at-home HIV test that gives results in under 40 minutes. The tests should be available in stores in October.

6 Jul 2012

Roche receives FDA approval for CMV viral load test

The U.S. Food and Drug Administration today approved the first DNA test to help health care professionals gauge the progress of anti-viral treatment in solid organ transplant patients undergoing cytomegalovirus (CMV) antiviral therapy.

6 Jul 2012

Study represents starting point for future clinical applications using propolis

A team of researchers from the University of Valencia, the Universitat Politècnica de València, the University Hospital La Fe and the Universitat Autònoma de Barcelona conducted in vitro studies of cytotoxicity (cellular affection) to assess the optimal concentration level of propolis in which this natural substance extracted from bee resin would offer the maximum protection against ionised radiation and not be toxic for blood cells.

6 Jul 2012